(Q35600888)

English

Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma

scientific article published on 25 August 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Polymeric nanoparticle-encapsulated hedgehog pathway inhibitor HPI-1 (NanoHHI) inhibits systemic metastases in an orthotopic model of human hepatocellular carcinoma (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

0 references

hepatocellular carcinoma

1 reference

based on heuristic

inferred from title

10

object named as

Anirban Maitra

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Yang Xu

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Venugopal Chenna

2

1 reference

Europe PubMed Central

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9 August 2017

Chaoxin Hu

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Hai-Xiang Sun

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Mehtab Khan

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Haibo Bai

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Xin-Rong Yang

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Qin-Feng Zhu

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Yun-Fan Sun

9

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Jia Fan

11

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9 August 2017

Robert A Anders

12

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9 August 2017

language of work or name

0 references

publication date

25 August 2011

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Europe PubMed Central

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9 August 2017

Clinical Cancer Research

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Europe PubMed Central

PubMed publication ID

9 August 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1291-1302

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Sorafenib suppresses postsurgical recurrence and metastasis of hepatocellular carcinoma in an orthotopic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Expression of sonic hedgehog signaling components in hepatocellular carcinoma and cyclopamine-induced apoptosis through Bcl-2 downregulation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Viral factors induce Hedgehog pathway activation in humans with viral hepatitis, cirrhosis, and hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Immunohistochemical staining of cancer stem cell markers in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Molecular classification and novel targets in hepatocellular carcinoma: recent advancements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

The identification of stem cells in human liver diseases and hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

CD133+ circulating haematopoietic progenitor cells predict for response to sorafenib plus erlotinib in non-small cell lung cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Smoothened mutation confers resistance to a Hedgehog pathway inhibitor in medulloblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Role of Hedgehog signaling pathway in proliferation and invasiveness of hepatocellular carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Hepatocellular carcinoma: current management and recent advances.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

The adventures of sonic hedgehog in development and repair. II. Sonic hedgehog and liver development, inflammation, and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Gli-1 siRNA induced apoptosis in Huh7 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Hedgehog signaling maintains resident hepatic progenitors throughout life

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Role for hedgehog signaling in hepatic stellate cell activation and viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Tissue repair and stem cell renewal in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

27 July 2018

Sonic hedgehog signaling protects human hepatocellular carcinoma cells against ionizing radiation in an autocrine manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Agents targeting the Hedgehog pathway for pancreatic cancer treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Interfering with resistance to smoothened antagonists by inhibition of the PI3K pathway in medulloblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Phase 2 open-label study of single-agent sorafenib in treating advanced hepatocellular carcinoma in a hepatitis B-endemic Asian population: presence of lung metastasis predicts poor response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Sorafenib in advanced hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Bile ductules and stromal cells express hedgehog ligands and/or hedgehog target genes in primary biliary cirrhosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Activation of the hedgehog pathway in human hepatocellular carcinomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Dendritic cell infiltration and prognosis of human hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Hedgehog signaling in human hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Communicating with Hedgehogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

A bipotential precursor population for pancreas and liver within the embryonic endoderm.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3233659

26 September 2018

Introduction: The burden of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21868763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Pitfalls in the classification of liver tumors]

1 reference

https://pubmed.ncbi.nlm.nih.gov/21868763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hedgehog-mediated mesenchymal–epithelial interactions modulate hepatic response to bile duct ligation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21868763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression patterns and polymorphisms of PTCH in Chinese hepatocellular carcinoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21868763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Debate: Resection for early hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21868763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor microvessel density as a predictor of recurrence after resection of hepatocellular carcinoma: a prospective study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21868763

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-11-0950

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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