(Q35616760)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Elimination of insulitis and augmentation of islet beta cell regeneration via induction of chimerism in overtly diabetic NOD mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Chunyan Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Ivan Todorov

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Mark Atkinson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Fouad Kandeel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Stephen Forman

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Defu Zeng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

language of work or name

English

0 references

publication date

31 January 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

25 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

2337-2342

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

Anti-CD3 and nasal proinsulin combination therapy enhances remission from recent-onset autoimmune diabetes by inducing Tregs

25 December 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Immunological reversal of autoimmune diabetes without hematopoietic replacement of beta cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Reversal of diabetes in non-obese diabetic mice without spleen cell-derived beta cell regeneration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Treatment of severe autoimmune disease by stem-cell transplantation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Opinion: Satisfaction (not) guaranteed: re-evaluating the use of animal models of type 1 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Epithelial-to-Mesenchymal Transition Generates Proliferative Human Islet Precursor Cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Islet Regeneration During the Reversal of Autoimmune Diabetes in NOD Mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Hematopoietic chimerism and central tolerance created by peripheral-tolerance induction without myeloablative conditioning

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1(Ala-Ala).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

The insulin gene in diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

A defect in interleukin 12-induced activation and interferon gamma secretion of peripheral natural killer T cells in nonobese diabetic mice suggests new pathogenic mechanisms for insulin-dependent diabetes mellitus.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Discordance of exocrine and endocrine growth after 90% pancreatectomy in rats

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Type-I diabetes: a chronic autoimmune disease of human, mouse, and rat.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Autoimmune diabetes and the circle of tolerance

12 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

ADA Outstanding Scientific Achievement Lecture 2004. Thirty years of investigating the autoimmune basis for type 1 diabetes: why can't we prevent or reverse this disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

Donor CD8+ T cells facilitate induction of chimerism and tolerance without GVHD in autoimmune NOD mice conditioned with anti-CD3 mAb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

Cure of overt diabetes in NOD mice by transient treatment with anti-lymphocyte serum and exendin-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

Bone marrow-derived stem cells initiate pancreatic regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

Increased vulnerability of newly forming beta cells to cytokine-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

NOD mice have a generalized defect in their response to transplantation tolerance induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

Donor CD8+ T cells mediate graft-versus-leukemia activity without clinical signs of graft-versus-host disease in recipients conditioned with anti-CD3 monoclonal antibody.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0611101104

Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/L

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1785362

A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development

25 September 2018

1 reference

12 December 2020

CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice

1 reference

12 December 2020

Preconditioning of NOD mice with anti-CD8 mAb and costimulatory blockade enhances chimerism and tolerance and prevents diabetes, while depletion of alpha beta-TCR+ and CD4+ cells negates the effect

1 reference

12 December 2020

Defective central tolerance induction in NOD mice: genomics and genetics

1 reference

12 December 2020

Functional defects and the influence of age on the frequency of CD4+ CD25+ T-cells in type 1 diabetes

1 reference

12 December 2020

Pancreatic regeneration in type 1 diabetes: dreams on a deserted islet?

1 reference

12 December 2020

Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0611101104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17267595%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference