(Q35621419)

English

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance

scientific article published on 31 October 2011

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Europe PubMed Central

PubMed publication ID

9 August 2017

Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

intestinal stem cell homeostasis

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Gene Ontology release 2020-05-02

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Fernando Camargo

10

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Fernando D Camargo

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Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Dawang Zhou

1

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Europe PubMed Central

PubMed publication ID

9 August 2017

Yongyou Zhang

2

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Europe PubMed Central

PubMed publication ID

9 August 2017

Hongtan Wu

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Evan Barry

4

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Europe PubMed Central

PubMed publication ID

9 August 2017

Yi Yin

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Earl Lawrence

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dawn Dawson

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Joseph E Willis

8

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Europe PubMed Central

PubMed publication ID

9 August 2017

Sanford D Markowitz

9

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Europe PubMed Central

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9 August 2017

Joseph Avruch

11

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9 August 2017

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publication date

31 October 2011

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Europe PubMed Central

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9 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

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9 August 2017

108

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Europe PubMed Central

PubMed publication ID

9 August 2017

49

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Europe PubMed Central

PubMed publication ID

9 August 2017

E1312-20

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Yap1 acts downstream of α-catenin to control epidermal proliferation

1 reference

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27 July 2018

Tissue-resident adult stem cell populations of rapidly self-renewing organs

1 reference

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27 July 2018

The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program

1 reference

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The Hippo Signaling Pathway in Development and Cancer

1 reference

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27 July 2018

Upstream regulation of the hippo size control pathway

1 reference

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27 July 2018

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

1 reference

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Notch: Implications of endogenous inhibitors for therapy

1 reference

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27 July 2018

The Hippo pathway regulates Wnt/beta-catenin signaling

1 reference

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

1 reference

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27 July 2018

Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

1 reference

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27 July 2018

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241824

27 July 2018

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241824

27 July 2018

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene

1 reference

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27 July 2018

Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse

1 reference

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Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer

1 reference

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27 July 2018

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

1 reference

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27 July 2018

Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

1 reference

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IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer

1 reference

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27 July 2018

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

1 reference

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The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells.

1 reference

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27 July 2018

Stem cells, self-renewal, and differentiation in the intestinal epithelium

1 reference

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27 July 2018

TEAD mediates YAP-dependent gene induction and growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241824

27 July 2018

MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241824

27 July 2018

YAP1 increases organ size and expands undifferentiated progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241824

27 July 2018

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241824

27 July 2018

Identification of stem cells in small intestine and colon by marker gene Lgr5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3241824

27 July 2018

Elucidation of a universal size-control mechanism in Drosophila and mammals

1 reference

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Mining the Wnt pathway for cancer therapeutics

1 reference

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Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras

1 reference

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Zebrafish prickle, a modulator of noncanonical Wnt/Fz signaling, regulates gastrulation movements.

1 reference

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Target disruption of the mutant beta-catenin gene in colon cancer cell line HCT116: preservation of its malignant phenotype

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Requirement of Math1 for secretory cell lineage commitment in the mouse intestine

1 reference

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The Ste20 group kinases as regulators of MAP kinase cascades

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1 reference

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Signalling downstream of activated mammalian Notch

1 reference

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Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size

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Hippo signaling: growth control and beyond

1 reference

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Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine.

1 reference

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1 reference

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Expression of Yes-associated protein in common solid tumors

1 reference

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Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion

1 reference

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Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

1 reference

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1 reference

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Analysis of liver development, regeneration, and carcinogenesis by genetic marking studies.

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25 September 2018

Identifiers

10.1073/PNAS.1110428108

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2011PNAS..108E1312Z

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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