(Q35623857)

9 August 2017

title

The genetic toolbox for Leishmania parasites (English)

1 reference

9 August 2017

Sigrid C Roberts

1

1 reference

9 August 2017

publication date

1 November 2011

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9 August 2017

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9 August 2017

volume

2

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9 August 2017

issue

6

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9 August 2017

page(s)

320-326

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Spermidine synthase is required for virulence of Leishmania donovani

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Generating knock-in parasites: integration of an ornithine decarboxylase transgene into its chromosomal locus in Leishmania donovani

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

The Hus1 homologue of Leishmania major encodes a nuclear protein that participates in DNA damage response.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Artificial linear episome-based protein expression system for protozoon Leishmania tarentolae.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Retention and loss of RNA interference pathways in trypanosomatid protozoans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

A rapid, efficient and economical method for generating leishmanial gene targeting constructs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Identification and characterization of a novel deoxyhypusine synthase in Leishmania donovani

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

TriTrypDB: a functional genomic resource for the Trypanosomatidae

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

A transposon toolkit for gene transfer and mutagenesis in protozoan parasites.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Regulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Demonstration of genetic exchange during cyclical development of Leishmania in the sand fly vector

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Leishmania donovani ornithine decarboxylase is indispensable for parasite survival in the mammalian host

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Leishmania invasion and phagosome biogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Construction and analysis of Leishmania tarentolae transgenic strains free of selection markers.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Global gene expression in Leishmania.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Comparative genomic analysis of three Leishmania species that cause diverse human disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Leishmania chagasi: a tetracycline-inducible cell line driven by T7 RNA polymerase.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Phenotypic characterization of a glucose transporter null mutant in Leishmania mexicana

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Leishmania donovani polyamine biosynthetic enzyme overproducers as tools to investigate the mode of action of cytotoxic polyamine analogs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Studies on the CPA cysteine peptidase in the Leishmania infantum genome strain JPCM5.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

A rapid, reversible, and tunable method to regulate protein function in living cells using synthetic small molecules

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

The genome of the kinetoplastid parasite, Leishmania major

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Identification of a DNA fragment that increases mitotic stability of episomal linear DNAs in Leishmania major

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

The ribosomal RNA gene promoter and adjacent cis-acting DNA sequences govern plasmid DNA partitioning and stable inheritance in the parasitic protozoan Leishmania

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

In vitro shuttle mutagenesis using engineered mariner transposons.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Mapping of a Leishmania major gene/locus that confers pentamidine resistance by deletion and insertion of transposable element

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

RNA interference in protozoan parasites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

The switch region on Leishmania major chromosome 1 is not required for mitotic stability or gene expression, but appears to be essential.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Life without transcriptional control? From fly to man and back again

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Putting the Leishmania genome to work: functional genomics by transposon trapping and expression profiling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Is lipophosphoglycan a virulence factor? A surprising diversity between Leishmania species

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Tetracycline regulated gene expression in Leishmania donovani

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Cell biology of Leishmania.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Leishmania phagolysosome: drug trafficking and protein sorting across the compartment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Selection against the dihydrofolate reductase-thymidylate synthase (DHFR-TS) locus as a probe of genetic alterations in Leishmania major.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Identification of genes mediating lipophosphoglycan biosynthesis by functional complementation of Leishmania donovani mutants.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Plasticity in chromosome number and testing of essential genes in Leishmania by targeting

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Double targeted gene replacement for creating null mutants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Creation of Null/+ mutants of the alpha-tubulin gene in Leishmania enriettii by gene cluster deletion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3242788

Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics

12 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

The gamma-glutamylcysteine synthetase gene of Leishmania is essential and involved in response to oxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin (GP63).

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

The Leishmania mexicana A600 genes are functionally required for amastigote replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Genetic analysis of spermidine synthase from Leishmania donovani

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

S-adenosylmethionine decarboxylase from Leishmania donovani. Molecular, genetic, and biochemical characterization of null mutants and overproducers

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Arginase plays a pivotal role in polyamine precursor metabolism in Leishmania. Characterization of gene deletion mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Lipophosphoglycan (LPG) and the identification of virulence genes in the protozoan parasite Leishmania

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

An effect of parasite-encoded arginase on the outcome of murine cutaneous leishmaniasis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Development of a recombinant Leishmania major strain sensitive to ganciclovir and 5-fluorocytosine for use as a live vaccine challenge in clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Generation of Leishmania mutants lacking antibiotic resistance genes using a versatile hit-and-run targeting strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Cloning, overexpression and characterization of Leishmania donovani squalene synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Leishmania: overexpression and comparative structural analysis of the stage-regulated meta 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Development of an inducible protein expression system based on the protozoan host Leishmania tarentolae

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Specificity of modified Drosophila mariner transposons in the identification of Leishmania genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Trans-kingdom transposition of the Drosophila element mariner within the protozoan Leishmania.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

New Mos1 mariner transposons suitable for the recovery of gene fusions in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Gene replacement in parasitic protozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

Ornithine Decarboxylase Gene Deletion Mutants ofLeishmania donovani

21 January 2018

2 references

https://api.crossref.org/works/10.4161%2FBBUG.2.6.18205

21 January 2018

12 December 2020

A telomere-mediated chromosome fragmentation approach to assess mitotic stability and ploidy alterations of Leishmania chromosomes

1 reference

12 December 2020

Leishmania donovani: long-term culture of axenic amastigotes at 37 degrees C

1 reference

12 December 2020

Thymidine kinase as a negative selectable marker in Leishmania major

1 reference

12 December 2020

Coupling of poly(A) site selection and trans-splicing in Leishmania

1 reference

12 December 2020

Genetic analysis of purine metabolism in Leishmania donovani

1 reference

12 December 2020

Protection against Leishmania major challenge infection in mice vaccinated with live recombinant parasites expressing a cytotoxic gene

1 reference

12 December 2020

FISH analysis reveals aneuploidy and continual generation of chromosomal mosaicism in Leishmania major

1 reference

12 December 2020

Identifiers

DOI

10.4161/BBUG.2.6.18205

1 reference

9 August 2017

1 reference

9 August 2017

1 reference