(Q35624622)

English

Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: implications for assessing children's risks from environmental agents

scientific article published on February 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

Europe PubMed Central

Physiologically based pharmacokinetic (PBPK) modeling of caffeine and theophylline in neonates and adults: implications for assessing children's risks from environmental agents (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

ChEBI release 2020-05-28

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Gary Ginsberg

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dale Hattis

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Abel Russ

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Babasaheb Sonawane

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

1 February 2004

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Journal of Toxicology and Environmental Health Part A

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

67

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

297-329

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Caffeine metabolism in premature infants

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Ontogeny of hepatic and renal systemic clearance pathways in infants: part II.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Caffeine metabolism in the newborn

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Physiologically based pharmacokinetics and the risk assessment process for methylene chloride.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Pharmacokinetic profile of caffeine in the premature newborn infant with apnea

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Caffeine and theophylline metabolism in newborn and adult human hepatocytes; comparison with adult rat hepatocytes

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (Part I).

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Precision and sensitivity of pharmacokinetic models for cancer risk assessment: tetrachloroethylene in mice, rats, and humans

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Noninvasive assessment of cardiac output in children using impedance cardiography

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Valproic acid hepatic fatalities. III. U.S. experience since 1986.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

RENAL EXTRACTION OF PARA-AMINOHIPPURATE IN INFANTS AND CHILDREN.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Dose-dependent pharmacokinetics of caffeine in humans: relevance as a test of quantitative liver function

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Review and evaluation of the potential impact of age- and gender-specific pharmacokinetic differences on tissue dosimetry

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Dose-dependency of caffeine metabolism with repeated dosing

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Uncertainty factors for chemical risk assessment. human variability in the pharmacokinetics of CYP1A2 probe substrates

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Valproic acid hepatic fatalities: a retrospective review

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Extrapolation of physiological parameters for physiologically based simulation models

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Assessing cancer risks from short-term exposures in children

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Evaluation of child/adult pharmacokinetic differences from a database derived from the therapeutic drug literature.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Metabolism of theophylline by cDNA-expressed human cytochromes P-450.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Biotransformation of caffeine by cDNA-expressed human cytochromes P-450.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Developmental expression of cytochrome P450 enzymes in human liver

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Uncertainties in pharmacokinetic modeling for perchloroethylene: II. Comparison of model predictions with data for a variety of different parameters

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

The ontogeny of human drug-metabolizing enzymes: phase I oxidative enzymes

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Perinatal Renal Pharmacology

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Physiologically based modeling of the inhalation kinetics of styrene in humans using a bayesian population approach

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Extrapolation of in vitro enzyme induction data to humans in vivo

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Partition coefficients and their uses

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Quantitative assessment of caffeine partial clearances in man.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

In vitro to in vivo extrapolation for trichloroethylene metabolism in humans.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Variance of microsomal protein and cytochrome P450 2E1 and 3A forms in adult human liver

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Theophylline toxicokinetics in premature newborns

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

The ontogeny of human drug-metabolizing enzymes: phase II conjugation enzymes and regulatory mechanisms

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Theophylline metabolism: Variation and genetics

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Evaluation of Cardiac Output by Thoracic Electrical Bioimpedance during Exercise in Normal Subjects

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Chloramphenicol toxicity in neonates: its incidence and prevention

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Clinical Pharmacokinetics of Theophylline

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Effect of smoking on caffeine clearance

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Effects of three antibiotics on theophylline kinetics

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Physiological modeling of age-specific changes in the pharmacokinetics of organic chemicals in children

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

A physiologically-based pharmacokinetic model assessment of methyl t-butyl ether in groundwater for a bathing and showering determination

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Toxicokinetics in infants and children in relation to the ADI and TDI.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Expression of CYP1A1 and CYP1A2 genes in human liver

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Clinical validation of cardiac output measurements using femoral artery thermodilution with direct Fick in ventilated children and infants.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Developmental aspects of theophylline metabolism in premature infants.

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Genetic polymorphisms of human N-acetyltransferase, cytochrome P450, glutathione-S-transferase, and epoxide hydrolase enzymes: relevance to xenobiotic metabolism and toxicity

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

The human CYP3A subfamily: practical considerations

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Measurement of cardiac output by thermal dilution in infants and children

1 reference

https://api.crossref.org/works/10.1080%2F15287390490273550

21 January 2018

Identifiers

10.1080/15287390490273550

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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