(Q35624898)

English

Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIα

scientific article published in 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIα (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Claus Schneider

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

4

object named as

Neil Osheroff

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

author name string

Odaine N Gordon

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Paula B Luis

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Rachel E Ashley

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

0 references

publication date

3 April 2015

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Chemical Research in Toxicology

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

989-996

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Degradation of Curcumin: From Mechanism to Biological Implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437832

12 July 2018

Unraveling curcumin degradation: autoxidation proceeds through spiroepoxide and vinylether intermediates en route to the main bicyclopentadione

1 reference

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12 July 2018

Phytochemicals as Anticancer and Chemopreventive Topoisomerase II Poisons

1 reference

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12 July 2018

Topoisomerase II and leukemia

1 reference

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12 July 2018

The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancer

1 reference

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12 July 2018

Facile synthesis of deuterated and [(14) C]labeled analogs of vanillin and curcumin for use as mechanistic and analytical tools

1 reference

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The role of cancer stem cells in the anti-carcinogenicity of curcumin

1 reference

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12 July 2018

Demethoxycurcumin, a major active curcuminoid from Curcuma longa, suppresses balloon injury induced vascular smooth muscle cell migration and neointima formation: an in vitro and in vivo study

1 reference

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New perspectives of curcumin in cancer prevention.

1 reference

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Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia

1 reference

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Bioactivity of turmeric-derived curcuminoids and related metabolites in breast cancer.

1 reference

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Drugging topoisomerases: lessons and challenges

1 reference

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12 July 2018

Oxidative metabolites of curcumin poison human type II topoisomerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437832

12 July 2018

Curcumin--from molecule to biological function.

1 reference

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12 July 2018

Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients.

1 reference

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12 July 2018

Autoxidative and cyclooxygenase-2 catalyzed transformation of the dietary chemopreventive agent curcumin

1 reference

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12 July 2018

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies.

1 reference

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12 July 2018

Targeting DNA topoisomerase II in cancer chemotherapy

1 reference

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12 July 2018

DNA topoisomerase II and its growing repertoire of biological functions.

1 reference

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12 July 2018

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

1 reference

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12 July 2018

Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300.

1 reference

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12 July 2018

Curcumin: from ancient medicine to current clinical trials.

1 reference

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12 July 2018

Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults

1 reference

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12 July 2018

Turmeric extracts containing curcuminoids prevent experimental rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437832

12 July 2018

Curcumin as a DNA topoisomerase II poison

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437832

12 July 2018

Antioxidants and oxidants regulated signal transduction pathways

1 reference

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Epidemiology of digestive tract cancers in India. V. Large and small bowel

1 reference

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12 July 2018

Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage

1 reference

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12 July 2018

Stability of curcumin in buffer solutions and characterization of its degradation products.

1 reference

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12 July 2018

Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetateinduced tumor promotion

1 reference

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12 July 2018

Vanillin and ferulic acid: not the major degradation products of curcumin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4437832

25 September 2018

Curcumin induces high levels of topoisomerase I- and II-DNA complexes in K562 leukemia cells.

1 reference

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Solvent effects on the rates and mechanisms of reaction of phenols with free radicals.

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25 September 2018

Abnormal solvent effects on hydrogen atom abstraction. 2. Resolution of the curcumin antioxidant controversy. The role of sequential proton loss electron transfer.

1 reference

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Effects of the phytochemicals, curcumin and quercetin, upon azoxymethane-induced colon cancer and 7,12-dimethylbenz[a]anthracene-induced mammary cancer in rats.

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25 September 2018

Spontaneous DNA lesions poison human topoisomerase IIalpha and stimulate cleavage proximal to leukemic 11q23 chromosomal breakpoints

1 reference

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Studies on curcumin and curcuminoids. VI. Kinetics of curcumin degradation in aqueous solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/25806475

12 December 2020

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inferred from PubMed ID database lookup

Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae

1 reference

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12 December 2020

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Use of yeast in the study of anticancer drugs targeting DNA topoisomerases: expression of a functional recombinant human DNA topoisomerase II alpha in yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/25806475

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/ACS.CHEMRESTOX.5B00009

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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