(Q35627849)

9 August 2017

title

A rapid and scalable system for studying gene function in mice using conditional RNA interference (English)

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9 August 2017

1 reference

6

Cornelius Miething

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Sang Yong Kim

Sang Yong Kim

3

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Ross A. Dickins

Ross A Dickins

9

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Johannes Zuber

Johannes Zuber

8

0 references

Gregory Hannon

13

Gregory J Hannon

1 reference

9 August 2017

Prem K Premsrirut

1

1 reference

9 August 2017

Lukas E Dow

2

1 reference

9 August 2017

Matthew Camiolo

4

1 reference

9 August 2017

Colin D Malone

5

1 reference

9 August 2017

Cornelius Miething

6

1 reference

9 August 2017

Claudio Scuoppo

7

1 reference

9 August 2017

Scott C Kogan

10

1 reference

9 August 2017

Kenneth R Shroyer

11

1 reference

9 August 2017

Raffaella Sordella

12

1 reference

9 August 2017

Scott W Lowe

14

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9 August 2017

language of work or name

English

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publication date

1 April 2011

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9 August 2017

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9 August 2017

volume

145

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9 August 2017

issue

1

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9 August 2017

page(s)

145-158

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describes a project that uses

9 August 2017

1 reference

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Selective activation of p53-mediated tumour suppression in high-grade tumours

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

The ARF tumor suppressor: structure, functions and status in cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Tissue-specific and reversible RNA interference in transgenic mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Adenomatous polyposis coli (APC) is required for normal development of skin and thymus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

RNAi Codex: a portal/database for short-hairpin RNA (shRNA) gene-silencing constructs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Second-generation shRNA libraries covering the mouse and human genomes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Methylation analysis of the adenomatous polyposis coli (APC) gene in adult T-cell leukemia/lymphoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Cre-lox-regulated conditional RNA interference from transgenes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Impact of p53 loss on reversal and recurrence of conditional Wnt-induced tumorigenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Deregulated beta-catenin induces a p53- and ARF-dependent growth arrest and cooperates with Ras in transformation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Genes involved in senescence and immortalization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

A transgenic mouse strain expressing four drug-selectable marker genes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Efficient selection for high-expression transfectants with a novel eukaryotic vector

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Functional identification of optimized RNAi triggers using a massively parallel sensor assay

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Stage-specific sensitivity to p53 restoration during lung cancer progression.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Specialized piRNA pathways act in germline and somatic tissues of the Drosophila ovary

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Paracrine factors of vascular endothelial cells facilitate cardiomyocyte differentiation of mouse embryonic stem cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Reversible gene knockdown in mice using a tight, inducible shRNA expression system

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Wnt/beta-catenin signaling in development and disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Generalized lacZ expression with the ROSA26 Cre reporter strain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244080

An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo

25 September 2018

1 reference

12 December 2020

Homozygosity for the Min allele of Apc results in disruption of mouse development prior to gastrulation

1 reference

12 December 2020

Derivation of mouse embryonic stem cells

1 reference

12 December 2020

Chimeric mouse tumor models reveal differences in pathway activation between ERBB family- and KRAS-dependent lung adenocarcinomas

1 reference

12 December 2020

10.1016/J.CELL.2011.03.012

Identifiers

DOI

1 reference

release_nvwldgdjqbg6npwjb7tksfx5ra

9 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nvwldgdjqbg6npwjb7tksfx5ra

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3244080

1 reference

9 August 2017

1 reference