(Q35635321)

9 August 2017

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title

Nucleoside transporters in chronic lymphocytic leukaemia (English)

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9 August 2017

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Pastor-Anglada M

1

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9 August 2017

Molina-Arcas M

2

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9 August 2017

Casado FJ

3

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9 August 2017

Bellosillo B

4

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9 August 2017

Colomer D

5

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9 August 2017

Gil J

6

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9 August 2017

1 March 2004

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9 August 2017

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9 August 2017

18

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9 August 2017

385-393

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9 August 2017

3

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2403271

9 August 2017

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cites work

Immunobiology of chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Alkylating agents and nucleoside analogues in the treatment of B cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Fludarabine. A review of its pharmacological properties and therapeutic potential in malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Cladribine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Nucleoside analogues in the treatment of haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Role of caspases and apoptosis-inducing factor (AIF) in cladribine-induced apoptosis of B cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Acadesine activates AMPK and induces apoptosis in B-cell chronic lymphocytic leukemia cells but not in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Modulating apoptosis pathways in low-grade B-cell malignancies using biological response modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Apoptosis induction with three nucleoside analogs on freshly isolated B-chronic lymphocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Fludarabine, cyclophosphamide and mitoxantrone in the treatment of resistant or relapsed chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

In vitro chemosensitivity of chronic lymphocytic leukaemia to purine analogues--correlation with clinical course.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Drug resistance to cytotoxic nucleoside analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Nucleoside transporters: molecular biology and implications for therapeutic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Functional and molecular characteristics of Na(+)-dependent nucleoside transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Electrogenic uptake of nucleosides and nucleoside-derived drugs by the human nucleoside transporter 1 (hCNT1) expressed in Xenopus laevis oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Identification and reconstitution of the nucleoside transporter of CEM human leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Fludarabine uptake mechanisms in B-cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Macrophages require different nucleoside transport systems for proliferation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Characterization of a novel Na+-dependent, guanosine-specific, nitrobenzylthioinosine-sensitive transporter in acute promyelocytic leukemia cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Interferon-gamma regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Mutation of residue 33 of human equilibrative nucleoside transporters 1 and 2 alters sensitivity to inhibition of transport by dilazep and dipyridamole

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

STAT1 mediates differentiation of chronic lymphocytic leukemia cells in response to Bryostatin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Sensitization of human breast cancer cells to gemcitabine by the protein kinase C modulator bryostatin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Inhibition of nucleoside transport by protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Mechanisms of resistance to nucleoside analogue chemotherapy in mantle cell lymphoma: a molecular case study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Es nucleoside transporter content of acute leukemia cells: role in cell sensitivity to cytarabine (araC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Mammalian ABC transporters in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in chronic lymphocytic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

A family of drug transporters: the multidrug resistance-associated proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Analysis of the MRP4 drug resistance profile in transfected NIH3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Functional expression of human intestinal Na+-dependent and Na+-independent nucleoside transporters in Xenopus laevis oocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Molecular cloning, functional expression and chromosomal localization of a cDNA encoding a human Na+/nucleoside cotransporter (hCNT2) selective for purine nucleosides and uridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Nucleoside analogues and nucleobases in cancer treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Deoxycoformycin-induced response in chronic lymphocytic leukaemia: deoxyadenosine toxicity in non-replicating lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

Chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

2-Chlorodeoxyadenosine Chemotherapy Triggers Programmed Cell Death in Normal and Malignant Lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Transport and mode of action of nucleoside derivatives used in chemical and antiviral therapies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

The equilibrative nucleoside transporter family, SLC29

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

The concentrative nucleoside transporter family, SLC28

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Regulation of nucleoside transport by lipopolysaccharide, phorbol esters, and tumor necrosis factor-alpha in human B-lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Lipopolysaccharide-induced apoptosis of macrophages determines the up-regulation of concentrative nucleoside transporters Cnt1 and Cnt2 through tumor necrosis factor-alpha-dependent and -independent mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Nucleoside transporters, bcl-2 and apoptosis in CLL cells exposed to nucleoside analogues in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Potentiation of 2-chlorodeoxyadenosine activity by bryostatin 1 in the resistant chronic lymphocytic leukemia cell line (WSU-CLL): association with increased ratios of dCK/5'-NT and Bax/Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Enhancement of retention and cytotoxicity of 2-chlorodeoxyadenosine in cultured human leukemic lymphoblasts by nitrobenzylthioinosine, an inhibitor of equilibrative nucleoside transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

MRP8, a new member of ABC transporter superfamily, identified by EST database mining and gene prediction program, is highly expressed in breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2403271

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2403271

1 reference

9 August 2017

1 reference