(Q35640638)

9 August 2017

Obesity is associated with hypothalamic injury in rodents and humans (English)

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9 August 2017

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Marcelo O Dietrich

6

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Matthias Tschöp

18

object named as

Matthias H Tschöp

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9 August 2017

Chun-Xia Yi

2

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Stephan J. Guyenet

4

object named as

Stephan J Guyenet

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9 August 2017

Joshua P Thaler

1

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9 August 2017

Ellen A Schur

3

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9 August 2017

Bang H Hwang

5

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9 August 2017

Xiaolin Zhao

7

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9 August 2017

David A Sarruf

8

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9 August 2017

Vitaly Izgur

9

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9 August 2017

Kenneth R Maravilla

10

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9 August 2017

Hong T Nguyen

11

1 reference

9 August 2017

Jonathan D Fischer

12

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9 August 2017

Miles E Matsen

13

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9 August 2017

Brent E Wisse

14

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9 August 2017

Gregory J Morton

15

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9 August 2017

Tamas L Horvath

16

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9 August 2017

Denis G Baskin

17

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9 August 2017

Michael W Schwartz

19

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9 August 2017

language of work or name

English

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publication date

27 December 2011

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Journal of Clinical Investigation

9 August 2017

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9 August 2017

122

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9 August 2017

1

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9 August 2017

153-162

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describes a project that uses

9 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3248304/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Autophagy in hypothalamic AgRP neurons regulates food intake and energy balance

1 reference

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Defective hypothalamic autophagy directs the central pathogenesis of obesity via the IkappaB kinase beta (IKKbeta)/NF-kappaB pathway

27 July 2018

1 reference

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Synaptic pruning by microglia is necessary for normal brain development

27 July 2018

1 reference

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Inflammatory links between obesity and metabolic disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Effects of chronic weight perturbation on energy homeostasis and brain structure in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Hsp70 and its molecular role in nervous system diseases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Autophagy, inflammation and neurodegenerative disease

27 July 2018

1 reference

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Changing face of microglia

27 July 2018

1 reference

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Obesity and leptin resistance: distinguishing cause from effect

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Agrp neurons mediate Sirt1's action on the melanocortin system and energy balance: roles for Sirt1 in neuronal firing and synaptic plasticity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Expanding the definition of hypothalamic obesity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Atypical protein kinase C activity in the hypothalamus is required for lipopolysaccharide-mediated sickness responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Molecular dissection of reactive astrogliosis and glial scar formation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

High-fat diet induces apoptosis of hypothalamic neurons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Microglial physiology: unique stimuli, specialized responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Insulin sensitivity: modulation by nutrients and inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Microglia: active sensor and versatile effector cells in the normal and pathologic brain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Mechanisms of leptin action and leptin resistance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Microglial activation and its implications in the brain diseases.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Inflammation and insulin resistance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Autophagic stress in neuronal injury and disease.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Astrocyte activation and reactive gliosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Obesity is associated with macrophage accumulation in adipose tissue

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Microglia-specific localisation of a novel calcium binding protein, Iba1

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Autophagy gone awry in neurodegenerative diseases

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Minireview: Inflammation and obesity pathogenesis: the hypothalamus heats up.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Tripartite synapses: astrocytes process and control synaptic information

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Endoplasmic reticulum stress plays a central role in development of leptin resistance

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Central nervous system control of food intake and body weight

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Conflicting MRI signals from gliosis and neuronal vacuolation in prion diseases.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Heat-shock protein protection.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248304

Deep white matter infarction: correlation of MR imaging and histopathologic findings

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22201683

12 December 2020

inferred from PubMed ID database lookup

Hippocampal pathology in refractory temporal lobe epilepsy: T2-weighted signal change reflects dentate gliosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22201683

12 December 2020

inferred from PubMed ID database lookup

Brain MR: pathologic correlation with gross and histopathology. 2. Hyperintense white-matter foci in the elderly

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22201683

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1172/JCI59660

1 reference

9 August 2017

1 reference

9 August 2017

1 reference