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Inflammatory links between obesity and metabolic disease
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Inflammatory links between obesity and metabolic disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
main subject
inflammation
0 references
obesity
0 references
author
Carey N. Lumeng
object named as
Carey N Lumeng
series ordinal
1
0 references
Alan R. Saltiel
object named as
Alan R Saltiel
series ordinal
2
0 references
language of work or name
English
0 references
publication date
1 June 2011
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
published in
Journal of Clinical Investigation
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
volume
121
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
page(s)
2111-2117
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
issue
6
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
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Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
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A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity
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Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance.
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Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity.
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Macrophages, cytokines and beta-cell death in Type 2 diabetes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
To catch up or not to catch up: is this the question? Lessons from animal models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Postprandial inflammation and endothelial dysfuction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Inflammation and metabolic disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
TLR4 links innate immunity and fatty acid-induced insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Dietary factors alter hepatic innate immune system in mice with nonalcoholic fatty liver disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
IKK-beta links inflammation to obesity-induced insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
The chemokine system in diverse forms of macrophage activation and polarization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Obesity is associated with macrophage accumulation in adipose tissue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
A central role for JNK in obesity and insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
The expression of TNF alpha by human muscle. Relationship to insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
8 July 2018
Adipose proinflammatory cytokine expression through sympathetic system is associated with hyperglycemia and insulin resistance in a rat ischemic stroke model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Natural killer T cells are involved in adipose tissues inflammation and glucose intolerance in diet-induced obese mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Endoplasmic reticulum stress plays a central role in development of leptin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Weight at birth and all-cause mortality in adulthood.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Increased number of islet-associated macrophages in type 2 diabetes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Postprandial variations of plasma inflammatory markers in abdominally obese men.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Metabolic and vascular effects of tumor necrosis factor-alpha blockade with etanercept in obese patients with type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
The fetal and childhood growth of persons who develop type 2 diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
25 October 2018
Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3104776
retrieved
9 December 2018
Adipocyte death, adipose tissue remodeling, and obesity complications
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21633179
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21633179
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Favored T helper 1 response in a mouse model of hepatosteatosis is associated with enhanced T cell-mediated hepatitis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/21633179
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1172/JCI57132
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
PMCID
3104776
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
PubMed ID
21633179
1 reference
stated in
Europe PubMed Central
PubMed ID
21633179
retrieved
5 August 2017
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