(Q35652151)

English

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins.

scientific article published on 3 June 2015

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16 February 2020

A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins (English)

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16 February 2020

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Florine Scholte

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16 February 2020

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16 February 2020

Martijn J van Hemert

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16 February 2020

Marjolein Kikkert

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16 February 2020

Peter Ten Dijke

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16 February 2020

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Adriaan H de Wilde

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16 February 2020

Kazimier F Wannee

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16 February 2020

Jelle J Goeman

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16 February 2020

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3 June 2015

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16 February 2020

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Journal of Virology

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16 February 2020

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16 February 2020

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16 February 2020

8318-8333

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Reverse genetics of SARS-related coronavirus using vaccinia virus-based recombination

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Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.

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Bat severe acute respiratory syndrome-like coronavirus ORF3b homologues display different interferon antagonist activities

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Activation of the Antiviral Kinase PKR and Viral Countermeasures

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Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus.

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Coronavirus gene 7 counteracts host defenses and modulates virus virulence

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Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

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A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma

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Comparative RNAi screening reveals host factors involved in enterovirus infection of polarized endothelial monolayers

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Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

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Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

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Accessory protein 5a is a major antagonist of the antiviral action of interferon against murine coronavirus

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Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

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Differential effects of the putative GBF1 inhibitors Golgicide A and AG1478 on enterovirus replication

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Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication.

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Integrity of the early secretory pathway promotes, but is not required for, severe acute respiratory syndrome coronavirus RNA synthesis and virus-induced remodeling of endoplasmic reticulum membranes

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Inhibition of protein kinase R activation and upregulation of GADD34 expression play a synergistic role in facilitating coronavirus replication by maintaining de novo protein synthesis in virus-infected cells

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A genome-wide genetic screen for host factors required for hepatitis C virus propagation

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The COPI system: molecular mechanisms and function

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Host cell factors in HIV replication: meta-analysis of genome-wide studies

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Coronaviruses post-SARS: update on replication and pathogenesis

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Discovery of insect and human dengue virus host factors

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A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

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Protein kinase C isoforms: Multi-functional regulators of cell life and death

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Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity

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RNA interference screen for human genes associated with West Nile virus infection

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Severe acute respiratory syndrome coronavirus 3a protein activates the mitochondrial death pathway through p38 MAP kinase activation.

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Drosophila RNAi screen identifies host genes important for influenza virus replication

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Mouse Hepatitis Coronavirus RNA Replication Depends on GBF1-Mediated ARF1 Activation

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A novel small-molecule inhibitor of protein kinase Ciota blocks transformed growth of non-small-cell lung cancer cells

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The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells

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7a protein of severe acute respiratory syndrome coronavirus inhibits cellular protein synthesis and activates p38 mitogen-activated protein kinase

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Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: role of ciliated cells in viral spread in the conducting airways of the lungs

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SARS coronavirus 7a protein blocks cell cycle progression at G0/G1 phase via the cyclin D3/pRb pathway

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Poliovirus proteins induce membrane association of GTPase ADP-ribosylation factor

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12 July 2018

Genome-wide RNAi screen reveals a specific sensitivity of IRES-containing RNA viruses to host translation inhibition

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Induction of IL-8 release in lung cells via activator protein-1 by recombinant baculovirus displaying severe acute respiratory syndrome-coronavirus spike proteins: identification of two functional regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Overexpression of 7a, a protein specifically encoded by the severe acute respiratory syndrome coronavirus, induces apoptosis via a caspase-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

A novel severe acute respiratory syndrome coronavirus protein, U274, is transported to the cell surface and undergoes endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Murine coronavirus replication induces cell cycle arrest in G0/G1 phase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Coronavirus replication complex formation utilizes components of cellular autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Differential requirements for COPI coats in formation of replication complexes among three genera of Picornaviridae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Murine coronavirus replication-induced p38 mitogen-activated protein kinase activation promotes interleukin-6 production and virus replication in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Glyceraldehyde-3-phosphate dehydrogenase is phosphorylated by protein kinase Ciota /lambda and plays a role in microtubule dynamics in the early secretory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

MEK5, a new target of the atypical protein kinase C isoforms in mitogenic signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Regulation of the G1 phase of the mammalian cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

12 July 2018

Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-κB-dependent gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

25 September 2018

Identification of host factors involved in coronavirus replication by quantitative proteomics analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

25 September 2018

Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

25 September 2018

The in vitro RNA synthesizing activity of the isolated arterivirus replication/transcription complex is dependent on a host factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

25 September 2018

Severe acute respiratory syndrome coronavirus ORF6 antagonizes STAT1 function by sequestering nuclear import factors on the rough endoplasmic reticulum/Golgi membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

25 September 2018

Aurothiomalate Inhibits Transformed Growth by Targeting the PB1 Domain of Protein Kinase Cι

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4524262

15 November 2018

Rab2 requires PKC iota/lambda to recruit beta-COP for vesicle formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26041291

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-scale RNAi screen for host factors required for HIV replication

1 reference

https://pubmed.ncbi.nlm.nih.gov/26041291

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.01029-15

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26041291%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26041291%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26041291%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

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