(Q35652268)

9 August 2017

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title

Interleukin-13 in asthma pathogenesis (English)

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9 August 2017

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1

Marsha Wills-Karp

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9 August 2017

1 March 2004

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Current Allergy and Asthma Reports

9 August 2017

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9 August 2017

4

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9 August 2017

2

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9 August 2017

123-131

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https://scigraph.springernature.com/pub.10.1007/s11882-004-0057-6

9 August 2017

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cites work

IL-13-dependent autocrine signaling mediates altered responsiveness of IgE-sensitized airway smooth muscle

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Selective induction of eotaxin release by interleukin-13 or interleukin-4 in human airway smooth muscle cells is synergistic with interleukin-1beta and is mediated by the interleukin-4 receptor alpha-chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells: a role for ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Up-regulation of cysteinyl leukotriene 1 receptor by IL-13 enables human lung fibroblasts to respond to leukotriene C4 and produce eotaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Interleukin-4- and interleukin-13-enhanced transforming growth factor-beta2 production in cultured human bronchial epithelial cells is attenuated by interferon-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Interleukin-13 induces proliferation of human airway epithelial cells in vitro via a mechanism mediated by transforming growth factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Interleukin-13 induces a hypersecretory ion transport phenotype in human bronchial epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Characterization of a calcium-activated chloride channel as a shared target of Th2 cytokine pathways and its potential involvement in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

The murine mCLCA3 (alias gob-5) protein is located in the mucin granule membranes of intestinal, respiratory, and uterine goblet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Granulocyte depletion and dexamethasone differentially modulate airways hyperreactivity, inflammation, mucus accumulation, and secretion induced by rmIL-13 or antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Direct effects of interleukin-13 on signaling pathways for physiological responses in cultured human airway smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Cutting edge: guinea pigs with a natural C3a-receptor defect exhibit decreased bronchoconstriction in allergic airway disease: evidence for an involvement of the C3a anaphylatoxin in the pathogenesis of asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11882-004-0057-6

Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma.

21 January 2018

1 reference

12 December 2020

Genetic variants of IL-13 signalling and human asthma and atopy

1 reference

12 December 2020

Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness

1 reference

12 December 2020

Increased arginase activity underlies allergen-induced deficiency of cNOS-derived nitric oxide and airway hyperresponsiveness

1 reference

12 December 2020

A novel mechanism by which interferon-gamma can regulate interleukin (IL)-13 responses. Evidence for intracellular stores of IL-13 receptor alpha -2 and their rapid mobilization by interferon-gamma

1 reference

12 December 2020

Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response

1 reference

12 December 2020

Interleukin-13 gene expression is regulated by GATA-3 in T cells: role of a critical association of a GATA and two GATG motifs

1 reference

12 December 2020

Cytokine regulation of IL-13Ralpha2 and IL-13Ralpha1 in vivo and in vitro.

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12 December 2020

Impaired development of Th2 cells in IL-13-deficient mice.

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12 December 2020

Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells

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12 December 2020

Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells

1 reference

12 December 2020

Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice

1 reference

12 December 2020

Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma

1 reference

12 December 2020

Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway

1 reference

12 December 2020

IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism

1 reference

12 December 2020

IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells

1 reference

12 December 2020

The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma

1 reference

12 December 2020

Requirement for IL-13 independently of IL-4 in experimental asthma

1 reference

12 December 2020

The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells

1 reference

12 December 2020

Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity

1 reference

12 December 2020

Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis

1 reference

12 December 2020

IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo

1 reference

12 December 2020

Interleukin-13: central mediator of allergic asthma

1 reference

12 December 2020

An IL-13 promoter polymorphism associated with increased risk of allergic asthma

1 reference

12 December 2020

Deletion of a coordinate regulator of type 2 cytokine expression in mice

1 reference

12 December 2020

CysLT1 receptor upregulation by TGF-β and IL-13 is associated with bronchial smooth muscle cell proliferation in response to LTD4

1 reference

12 December 2020

Eosinophils Express Functional IL-13 in Eosinophilic Inflammatory Diseases

1 reference

12 December 2020

Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity

1 reference

12 December 2020

Specific immunotherapy prevents increased levels of allergen-specific IL-4- and IL-13-producing cells during pollen season

1 reference

12 December 2020

The role of interleukin-4 and interleukin-13 in the non-immunologic aspects of asthma pathogenesis

1 reference

12 December 2020

Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

1 reference

12 December 2020

Upregulation of IL-13 concentration in vivo by the IL13 variant associated with bronchial asthma

1 reference

12 December 2020

The distribution of IL-13 receptor alpha1 expression on B cells, T cells and monocytes and its regulation by IL-13 and IL-4.

1 reference

12 December 2020

A role for the C3a anaphylatoxin receptor in the effector phase of asthma

1 reference

12 December 2020

Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma

1 reference

12 December 2020

Dysregulation of IL-13 production by cord blood CD4+ T cells is associated with the subsequent development of atopic disease in infants

1 reference

12 December 2020

Interleukin-13 stimulates the proliferation of lung myofibroblasts via a signal transducer and activator of transcription-6-dependent mechanism: a possible mechanism for the development of airway fibrosis in asthma

1 reference

12 December 2020

The absence of interleukin 9 does not affect the development of allergen-induced pulmonary inflammation nor airway hyperreactivity.

1 reference

12 December 2020

IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lung

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12 December 2020

An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response

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12 December 2020

IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells

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12 December 2020

Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma

1 reference

12 December 2020

Critical role for IL-13 in the development of allergen-induced airway hyperreactivity

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12 December 2020

Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils

1 reference

12 December 2020

Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

1 reference

12 December 2020

The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3

1 reference

12 December 2020

Haplotypes of the 5' region of the IL-4 gene and SNPs in the intergene sequence between the IL-4 and IL-13 genes are associated with atopic asthma

1 reference

12 December 2020

A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children

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12 December 2020

Lack of association between a polymorphism in the interleukin-13 gene and total serum immunoglobulin E level among nuclear families in Costa Rica

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12 December 2020

Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema

1 reference

12 December 2020

Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy

1 reference

12 December 2020

IL-13 expression at the sites of allergen challenge in patients with asthma

1 reference

12 December 2020

Pulmonary overexpression of IL-9 induces Th2 cytokine expression, leading to immune pathology

1 reference

12 December 2020

A novel T cell-regulated mechanism modulating allergen-induced airways hyperreactivity in BALB/c mice independently of IL-4 and IL-5.

1 reference

12 December 2020

Interleukin-4 is required for the induction of lung Th2 mucosal immunity

1 reference

12 December 2020

Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

1 reference

12 December 2020

10.1007/S11882-004-0057-6

Identifiers

DOI

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9 August 2017

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PubMed ID

14769261