(Q35654904)

9 August 2017

Midbrain dopamine neurons in Parkinson's disease exhibit a dysregulated miRNA and target-gene network (English)

1 reference

9 August 2017

1 reference

Kai-Christian Sonntag

1 reference

ORCID Public Data File 2021

author name string

Christine E Briggs

1

1 reference

9 August 2017

Yulei Wang

2

1 reference

9 August 2017

Benjamin Kong

3

1 reference

9 August 2017

Tsung-Ung W Woo

4

1 reference

9 August 2017

Lakshmanan K Iyer

5

1 reference

9 August 2017

Kai C Sonntag

6

1 reference

9 August 2017

language of work or name

English

0 references

publication date

3 June 2015

1 reference

9 August 2017

1 reference

9 August 2017

1618

1 reference

9 August 2017

111-121

1 reference

describes a project that uses

9 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4522231

inferred from PubMed Central ID database lookup

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Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters

12 July 2018

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Construction and analysis of the protein-protein interaction networks based on gene expression profiles of Parkinson's disease

12 July 2018

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12 July 2018

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12 July 2018

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RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation

12 July 2018

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Regulation of the VHL/HIF-1 pathway by DJ-1

12 July 2018

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Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner

12 July 2018

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Insulin, IGF-1 and GLP-1 signaling in neurodegenerative disorders: targets for disease modification?

12 July 2018

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Menin is required for optimal processing of the microRNA let-7a

12 July 2018

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miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling.

12 July 2018

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Loss of PINK1 attenuates HIF-1α induction by preventing 4E-BP1-dependent switch in protein translation under hypoxia

12 July 2018

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MiR-15a-16 represses Cripto and inhibits NSCLC cell progression

12 July 2018

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Analysis of novel NEFL mRNA targeting microRNAs in amyotrophic lateral sclerosis

12 July 2018

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The transcription factor CCAAT enhancer-binding protein β protects rat cerebellar granule neurons from apoptosis through its transcription-activating isoforms

12 July 2018

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The over-expression of miR-200a in the hypothalamus of ob/ob mice is linked to leptin and insulin signaling impairment

12 July 2018

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LIM-domain-only proteins: multifunctional nuclear transcription coregulators that interacts with diverse proteins

12 July 2018

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Causal analysis approaches in Ingenuity Pathway Analysis

12 July 2018

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RISC in PD: the impact of microRNAs in Parkinson's disease cellular and molecular pathogenesis

12 July 2018

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Over-expression of an inactive mutant cathepsin D increases endogenous alpha-synuclein and cathepsin B activity in SH-SY5Y cells

12 July 2018

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Advances with microRNAs in Parkinson's disease research

12 July 2018

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A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1.

12 July 2018

1 reference

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Iron deficiency alters expression of dopamine-related genes in the ventral midbrain in mice.

12 July 2018

1 reference

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miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit.

12 July 2018

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Functions of BCL-X L at the Interface between Cell Death and Metabolism

12 July 2018

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The DEAD box proteins DDX5 (p68) and DDX17 (p72): multi-tasking transcriptional regulators

12 July 2018

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PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage

12 July 2018

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miRNAs and their putative roles in the development and progression of Parkinson's disease

12 July 2018

1 reference

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Synaptic retinoic acid signaling and homeostatic synaptic plasticity

12 July 2018

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MicroRNAs in the regulation of TLR and RIG-I pathways

12 July 2018

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Gravin orchestrates protein kinase A and β2-adrenergic receptor signaling critical for synaptic plasticity and memory.

12 July 2018

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MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma

12 July 2018

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miRNA-7-5p inhibits melanoma cell migration and invasion.

12 July 2018

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MicroRNA-205 regulates the expression of Parkinson's disease-related leucine-rich repeat kinase 2 protein.

12 July 2018

1 reference

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L166P mutant DJ-1 promotes cell death by dissociating Bax from mitochondrial Bcl-XL.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Human midbrain precursors activate the expected developmental genetic program and differentiate long-term to functional A9 dopamine neurons in vitro. Enhancement by Bcl-X(L).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Molecular basis of axonal dysfunction and traffic impairments in CMT.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

miR-132 regulates the differentiation of dopamine neurons by directly targeting Nurr1 expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Converging miRNA functions in diverse brain disorders: a case for miR-124 and miR-126.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

MicroRNAs in metabolism and metabolic diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

The Lin28/let-7 axis regulates glucose metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Reduced miR-128 in breast tumor-initiating cells induces chemotherapeutic resistance via Bmi-1 and ABCC5.

12 July 2018

1 reference

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Neuronal type-specific gene expression profiling and laser-capture microdissection

12 July 2018

1 reference

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Epidemiology and etiology of Parkinson's disease: a review of the evidence

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat

12 July 2018

1 reference

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Variants in estrogen-related genes and risk of Parkinson's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

The Beclin 1 network regulates autophagy and apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Vav3 is involved in GABAergic axon guidance events important for the proper function of brainstem neurons controlling cardiovascular, respiratory, and renal parameters.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Genes, proteins and complexes: the multifaceted nature of FHL family proteins in diverse tissues

12 July 2018

1 reference

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Munc18-1 as a key regulator of neurosecretion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1 alpha and induction of autophagy in SH-SY5Y cells

12 July 2018

1 reference

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Roles for miRNA-378/378* in adipocyte gene expression and lipogenesis

12 July 2018

1 reference

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MicroRNAs and deregulated gene expression networks in neurodegeneration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Polymorphisms of caffeine metabolism and estrogen receptor genes and risk of Parkinson's disease in men and women

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Vav3-deficient mice exhibit a transient delay in cerebellar development

12 July 2018

1 reference

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MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Repression of alpha-synuclein expression and toxicity by microRNA-7.

12 July 2018

1 reference

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A novel and universal method for microRNA RT-qPCR data normalization

12 July 2018

1 reference

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NF-kappaB regulation: the nuclear response

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

MicroRNAs: target recognition and regulatory functions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Invited Article: Nervous system pathology in sporadic Parkinson disease

12 July 2018

1 reference

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lumi: a pipeline for processing Illumina microarray

12 July 2018

1 reference

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Review: Familial Parkinson's disease--genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

MicroRNAs (miRNAs) in neurodegenerative diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

A MicroRNA feedback circuit in midbrain dopamine neurons

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Effects of gender on nigral gene expression and parkinson disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Neurotrophin/Trk receptor signaling mediates C/EBPalpha, -beta and NeuroD recruitment to immediate-early gene promoters in neuronal cells and requires C/EBPs to induce immediate-early gene transcription.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Bioconductor: open software development for computational biology and bioinformatics

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Evidence for a satellite secretory pathway in neuronal dendritic spines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Recent trends in receptor analysis techniques and instrumentation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Huwe1 as a therapeutic target for neural injury

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Genetic polymorphisms in VDR, ESR1 and ESR2 genes may contribute to susceptibility to Parkinson's disease: a meta-analysis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

MiRNA-145 is involved in the development of resistin-induced insulin resistance in HepG2 cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

miR-135a targets IRS2 and regulates insulin signaling and glucose uptake in the diabetic gastrocnemius skeletal muscle.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Vav deficiency impedes peripheral nerve regeneration in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

miRNA expression profiling: from reference genes to global mean normalization.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

How to choose a normalization strategy for miRNA quantitative real-time (qPCR) arrays

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Proteome analysis of ventral midbrain in MPTP-treated normal and L1cam transgenic mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

L1 neural cell adhesion molecule is a survival factor for fetal dopaminergic neurons

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4522231

Lysosomal enzyme cathepsin B enhances the aggregate forming activity of exogenous α-synuclein fibrils

25 September 2018

1 reference

PubMed

12 December 2020

Etiology and pathogenesis of Parkinson's disease

1 reference

PubMed

12 December 2020

Huwe1: a possible role in PD

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

10.1016/J.BRAINRES.2015.05.021

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference