(Q33889585)

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Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death.

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21541762%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Expression analysis of dopaminergic neurons in Parkinson's disease and aging links transcriptional dysregulation of energy metabolism to cell death (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21541762%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Parkinson's disease

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based on heuristic

inferred from title

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based on heuristic

inferred from title

transcriptional dysregulation

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based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Thomas Meitinger

8

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30 January 2020

Christopher Morris

2

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30 January 2020

4

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30 January 2020

5

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30 January 2020

Douglass Matthew Turnbull

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30 January 2020

Holger Prokisch

10

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30 January 2020

Thomas Klopstock

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Thomas Klopstock

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30 January 2020

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Katharina Heim

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30 January 2020

Matthias Elstner

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Matthias Elstner

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30 January 2020

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Evelyn Jaros

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30 January 2020

publication date

4 May 2011

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30 January 2020

Acta Neuropathologica

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30 January 2020

122

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30 January 2020

1

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30 January 2020

75-86

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30 January 2020

Expanding insights of mitochondrial dysfunction in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Target identification for CNS diseases by transcriptional profiling.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Methodological considerations for gene expression profiling of human brain.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Multi-site control and regulation of mitochondrial energy production.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Neural mechanisms of ageing and cognitive decline

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Analysis of gene expression in Parkinson's disease: possible involvement of neurotrophic support and axon guidance in dopaminergic cell death

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Staging of brain pathology related to sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

DNA chip technology in brain banks: confronting a degrading world.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Ageing of substantia nigra in humans: cell loss may be compensated by hypertrophy

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

A network-based analysis of systemic inflammation in humans

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Effects of gender on nigral gene expression and parkinson disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

'Rejuvenation' protects neurons in mouse models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Glial degeneration and reactive gliosis in alpha-synucleinopathies: the emerging concept of primary gliodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Parkinson's disease: mechanisms and models

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Update in the epidemiology of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

The mitochondrial proteome database: MitoP2.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Genetics of Parkinson disease: paradigm shifts and future prospects.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Ageing and Parkinson's disease: substantia nigra regional selectivity

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Acetyl-CoA synthetase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Anti-inflammatory drugs and risk of Parkinson disease: A meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Molecular pathogenesis of Parkinson disease: insights from genetic studies

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Strategies for the protection of dopaminergic neurons against neurotoxicity.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Expression profiling of substantia nigra in Parkinson disease, progressive supranuclear palsy, and frontotemporal dementia with parkinsonism.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Transcriptional control of mitochondrial biogenesis and function

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Estrogenic control of mitochondrial function and biogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

A genomic pathway approach to a complex disease: axon guidance and Parkinson disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Mitochondrial biogenesis and healthy aging

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Gene regulation and DNA damage in the ageing human brain

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Robust dysregulation of gene expression in substantia nigra and striatum in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Progress in the use of microarray technology to study the neurobiology of disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Towards a pathway definition of Parkinson's disease: a complex disorder with links to cancer, diabetes and inflammation

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Caffeine activates the PI3K/Akt pathway and prevents apoptotic cell death in a Parkinson's disease model of SH-SY5Y cells

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Genomic aspects of sporadic Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Dopamine and aging: intersecting facets

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Morphometry of the human substantia nigra in ageing and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

A novel mitochondrial carnitine-acylcarnitine translocase induced by partial hepatectomy and fasting

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Gene expression profiling of substantia nigra dopamine neurons: further insights into Parkinson's disease pathology

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Evidence for gender-specific transcriptional profiles of nigral dopamine neurons in Parkinson disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Histological changes of the dopaminergic nigrostriatal system in aging

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Calcium, ageing, and neuronal vulnerability in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

A cross-study transcriptional analysis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Akt signal transduction dysfunction in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Parkinson disease: primacy of age as a risk factor for mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Transcriptional changes in multiple system atrophy and Parkinson's disease putamen

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0828-9

21 January 2018

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10.1007/S00401-011-0828-9

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21541762%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21541762%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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