(Q35665058)

English

The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium

scientific article published on 29 August 2011

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium (English)

1 reference

Europe PubMed Central

9 August 2017

0 references

Matthew C. Walker

object named as

Matthew C Walker

10

0 references

author name string

Pishan Chang

1

1 reference

Europe PubMed Central

9 August 2017

Benoit Orabi

2

1 reference

Europe PubMed Central

9 August 2017

Rania M Deranieh

3

1 reference

Europe PubMed Central

9 August 2017

Manik Dham

4

1 reference

Europe PubMed Central

9 August 2017

Oliver Hoeller

5

1 reference

Europe PubMed Central

9 August 2017

Jakob A Shimshoni

6

1 reference

Europe PubMed Central

9 August 2017

Boris Yagen

7

1 reference

Europe PubMed Central

9 August 2017

Meir Bialer

8

1 reference

Europe PubMed Central

9 August 2017

Miriam L Greenberg

9

1 reference

Europe PubMed Central

9 August 2017

Robin S B Williams

11

1 reference

Europe PubMed Central

9 August 2017

publication date

29 August 2011

1 reference

Europe PubMed Central

9 August 2017

Disease Models & Mechanisms

1 reference

Europe PubMed Central

9 August 2017

5

1 reference

Europe PubMed Central

9 August 2017

1

1 reference

Europe PubMed Central

9 August 2017

115-124

1 reference

Europe PubMed Central

9 August 2017

Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Molecular pharmacology in a simple model system: implicating MAP kinase and phosphoinositide signalling in bipolar disorder.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Genetic control of lithium sensitivity and regulation of inositol biosynthetic genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Structure-function studies for the panacea, valproic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

The mood stabiliser lithium suppresses PIP3 signalling in Dictyostelium and human cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Highlighting the role of Ras and Rap during Dictyostelium chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Attenuation of phospholipid signaling provides a novel mechanism for the action of valproic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Valproic Acid: second generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Towards a molecular understanding of human diseases using Dictyostelium discoideum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Regulation of chemotaxis by the orchestrated activation of Ras, PI3K, and TOR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Pharmacogenetics in model systems: defining a common mechanism of action for mood stabilisers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core struc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Pharmacodynamic properties of N-dipropylacetic acid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

A common mechanism of action for three mood-stabilizing drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

A Dictyostelium nuclear phosphatidylinositol phosphate kinase required for developmental gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Loss of a prolyl oligopeptidase confers resistance to lithium by elevation of inositol (1,4,5) trisphosphate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Role of phospholipase C in Dictyostelium: formation of inositol 1,4,5-trisphosphate and normal development in cells lacking phospholipase C activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Strategies for the development of drugs for pharmacoresistant epilepsies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

The effects of analogues of valproic acid on seizures induced by pentylenetetrazol and GABA content in brain of mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

The effects of lithium ion and other agents on the activity of myo-inositol-1-phosphatase from bovine brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Enhanced inositide turnover in brain during bicuculline-induced status epilepticus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Intravenous valproate: onset and duration of anticonvulsant activity against a series of electroconvulsions in comparison with diazepam and phenytoin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

12 July 2018

Quantifying in vivo phosphoinositide turnover in chemotactically competent Dictyostelium cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Sodium valproate: an old drug with new roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Employing multiple models, methods and mechanisms in bipolar disorder research.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Effect of valproate derivatives on human brain myo-inositol-1-phosphate (MIP) synthase activity and amphetamine-induced rearing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Specificity of mood stabilizer action on neuronal growth cones.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Valproate decreases inositol biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Lithium and valproate decrease inositol mass and increase expression of the yeast INO1 and INO2 genes for inositol biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Effects of new valproate derivatives on epileptiform discharges induced by pentylenetetrazole or low Mg2+ in rat entorhinal cortex-hippocampus slices.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

25 September 2018

Chemotaxis in the Absence of PIP3 Gradients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3255550

15 November 2018

The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21876211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Effects of Central Nervous System-Active Valproic Acid Constitutional Isomers, Cyclopropyl Analogs, and Amide Derivatives on Neuronal Growth Cone Behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/21876211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myo-inositol-1-phosphate (MIP) synthase inhibition: in-vivo study in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21876211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of 4-methyloctanoic acid and other medium chain-length fatty acid constituents of ovine tissue lipids

1 reference

https://pubmed.ncbi.nlm.nih.gov/21876211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute anticonvulsant activity of structural analogues of valproic acid and changes in brain GABA and aspartate content

1 reference

https://pubmed.ncbi.nlm.nih.gov/21876211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological evaluation of various metabolites and analogues of valproic acid. Anticonvulsant and toxic potencies in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21876211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of valproate analogues in rats. IV. Anticonvulsant action and neurotoxicity of octanoic acid, cyclohexanecarboxylic acid, and 1-methyl-1-cyclohexanecarboxylic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/21876211

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1242/DMM.008029

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

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