(Q35666031)

9 August 2017

title

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation (English)

1 reference

9 August 2017

Darren N Saunders

10

0 references

Mark R. Wilson

Mark R Wilson

9

0 references

Marie Ranson

Marie Ranson

11

0 references

Andreas Suhrbier

8

Andreas Suhrbier

1 reference

9 August 2017

Danny M Hatters

6

0 references

Justin Yerbury

2

Justin J Yerbury

1 reference

9 August 2017

4

Robert F Shearer

1 reference

9 August 2017

Jodi A Lee

1

1 reference

9 August 2017

Natalie Farrawell

3

1 reference

9 August 2017

Patrick Constantinescu

5

1 reference

9 August 2017

Wayne A Schroder

7

1 reference

9 August 2017

language of work or name

English

0 references

publication date

17 June 2015

1 reference

9 August 2017

1 reference

9 August 2017

volume

10

1 reference

9 August 2017

issue

6

1 reference

9 August 2017

page(s)

e0130136

1 reference

Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

17 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

12 July 2018

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Misfolded polyglutamine, polyalanine, and superoxide dismutase 1 aggregate via distinct pathways in the cell

12 July 2018

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12 July 2018

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TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation

12 July 2018

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PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone

12 July 2018

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The small heat shock proteins αB-crystallin and Hsp27 suppress SOD1 aggregation in vitro

12 July 2018

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12 July 2018

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12 July 2018

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Forty years later and the role of plasminogen activator inhibitor type 2/SERPINB2 is still an enigma.

12 July 2018

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The role of SerpinB2 in immunity

12 July 2018

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Human papilloma virus transformed CaSki cells constitutively express high levels of functional SerpinB2.

12 July 2018

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Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial

12 July 2018

1 reference

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Tracking mutant huntingtin aggregation kinetics in cells reveals three major populations that include an invariant oligomer pool.

12 July 2018

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Conformation sensors that distinguish monomeric proteins from oligomers in live cells

12 July 2018

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A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity

12 July 2018

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Ubiquitin-binding domains - from structures to functions

12 July 2018

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Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity

12 July 2018

1 reference

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The CD-loop of PAI-2 (SERPINB2) is redundant in the targeting, inhibition and clearance of cell surface uPA activity.

12 July 2018

1 reference

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Functional roles of ubiquitin-like domain (ULD) and ubiquitin-binding domain (UBD) containing proteins

12 July 2018

1 reference

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Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein

12 July 2018

1 reference

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Crystallin proteins and amyloid fibrils

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Protein misfolding inside cells: the case of huntingtin and Huntington's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Misfolded proteins partition between two distinct quality control compartments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Bimolecular fluorescence complementation (BiFC) analysis as a probe of protein interactions in living cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Revisiting the biological roles of PAI2 (SERPINB2) in cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Adapting proteostasis for disease intervention

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Protein misfolding, functional amyloid, and human disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Application and analysis of the GFPu family of ubiquitin-proteasome system reporters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

The mammalian unfolded protein response

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysis.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Interaction of plasminogen activator inhibitor-2 and proteasome subunit, beta type 1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Ubiquitin-associated (UBA) domains in Rad23 bind ubiquitin and promote inhibition of multi-ubiquitin chain assembly

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Impairment of the ubiquitin-proteasome system by protein aggregation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Hsp47: a molecular chaperone that interacts with and stabilizes correctly-folded procollagen

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

The plasminogen activator inhibitor-2 gene is not required for normal murine development or survival

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Alpha 1-antichymotrypsin interaction with A beta (1-42) does not inhibit fibril formation but attenuates the peptide toxicity.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Microglia express the type 2 plasminogen activator inhibitor in the brain of control subjects and patients with Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Alpha 1-antichymotrypsin regulates Alzheimer beta-amyloid peptide fibril formation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Biological and clinical aspects of plasminogen activator inhibitor type 2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Immunochemical identification of the serine protease inhibitor alpha 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease.

12 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

12 July 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0130136

Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

ANS binding reveals common features of cytotoxic amyloid species

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4470917

Clusterin Has Chaperone-like Activity Similar to That of Small Heat Shock Proteins

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0130136

alpha-1-antichymotrypsin interaction with A beta (1-40) inhibits fibril formation but does not affect the peptide toxicity

21 January 2018

1 reference

12 December 2020

Plasminogen activator inhibitor type 2: still an enigmatic serpin but a model for gene regulation

1 reference

12 December 2020

Molecular chaperones: the modular evolution of cellular networks

1 reference

12 December 2020

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0130136

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference