(Q35668299)

English

HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway.

scientific article published on 19 June 2015

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17 February 2020

HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-κB Pathway (English)

1 reference

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17 February 2020

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toll-like receptor

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based on heuristic

inferred from title

5

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17 February 2020

Elmostafa Bahraoui

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17 February 2020

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Nawal Ben Haij

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17 February 2020

Rémi Planès

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17 February 2020

Kaoutar Leghmari

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17 February 2020

Manutea Serrero

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17 February 2020

Lbachir BenMohamed

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17 February 2020

Jacques Izopet

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17 February 2020

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17 February 2020

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17 February 2020

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17 February 2020

e0129425

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17 February 2020

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Creative Commons Attribution 4.0 International

19 June 2015

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0 references

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Genomic HIV RNA induces innate immune responses through RIG-I-dependent sensing of secondary-structured RNA

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Tits and bits of HIV Tat protein.

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Viral exploitation of host SOCS protein functions

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12 July 2018

Biomarkers of immune dysfunction in HIV.

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12 July 2018

Suppressor of cytokine signaling 3 inhibits antiviral IFN-beta signaling to enhance HIV-1 replication in macrophages

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12 July 2018

Role of HIV-1 Tat in AIDS pathogenesis: its effects on cytokine dysregulation and contributions to the pathogenesis of opportunistic infection.

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12 July 2018

Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease

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Role of chemokine and cytokine polymorphisms in the progression of HIV-1 disease

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12 July 2018

Differential induction of interleukin-10 in monocytes by HIV-1 clade B and clade C Tat proteins.

1 reference

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12 July 2018

Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade

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12 July 2018

HIV-1 lentiviral vector immunogenicity is mediated by Toll-like receptor 3 (TLR3) and TLR7.

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12 July 2018

Chloroquine modulates HIV-1-induced plasmacytoid dendritic cell alpha interferon: implication for T-cell activation

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12 July 2018

HIV-1 Tat and heparan sulfate proteoglycan interaction: a novel mechanism of lymphocyte adhesion and migration across the endothelium

1 reference

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12 July 2018

Differential effects of HIV type 1 clade B and clade C Tat protein on expression of proinflammatory and antiinflammatory cytokines by primary monocytes

1 reference

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12 July 2018

IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

1 reference

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12 July 2018

Human immunodeficiency virus-1 Tat protein: immunological facets of a transcriptional activator

1 reference

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12 July 2018

SOCS1 is an inducible host factor during HIV-1 infection and regulates the intracellular trafficking and stability of HIV-1 Gag.

1 reference

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Immune activation and inflammation in HIV-1 infection: causes and consequences

1 reference

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12 July 2018

HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells

1 reference

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SOCS proteins, cytokine signalling and immune regulation

1 reference

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12 July 2018

HIV-1 Tat triggers TGF-beta production and NK cell apoptosis that is prevented by pertussis toxin B.

1 reference

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

1 reference

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Dendritic-cell interactions with HIV: infection and viral dissemination

1 reference

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12 July 2018

1 reference

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12 July 2018

Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection

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Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

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1 reference

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Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor-viral RNA interactions

1 reference

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Integrin alphavbeta3 as a target for blocking HIV-1 Tat-induced endothelial cell activation in vitro and angiogenesis in vivo.

1 reference

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12 July 2018

Human immunodeficiency virus type 1 Tat protein induces an intracellular calcium increase in human monocytes that requires DHP receptors: involvement in TNF-alpha production

1 reference

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12 July 2018

HIV-1 Tat enhances Kaposi sarcoma-associated herpesvirus (KSHV) infectivity

1 reference

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12 July 2018

Cytokines and HIV-1: interactions and clinical implications

1 reference

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12 July 2018

Regulation of cell death: the calcium-apoptosis link

1 reference

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Viral and cellular cytokines as therapeutic targets in AIDS-related lymphoproliferative disorders

1 reference

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12 July 2018

Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha

1 reference

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12 July 2018

Pro- and anti-inflammatory cytokines in human immunodeficiency virus infection and acquired immunodeficiency syndrome

1 reference

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12 July 2018

HIV-1 Tat protein induces interleukin-10 in human peripheral blood monocytes: involvement of protein kinase C-betaII and -delta

1 reference

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12 July 2018

Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway

1 reference

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12 July 2018

Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1

1 reference

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12 July 2018

Internalization of HIV-1 tat requires cell surface heparan sulfate proteoglycans

1 reference

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12 July 2018

From the outside in: extracellular activities of HIV Tat.

1 reference

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12 July 2018

Induction of the chemokines interleukin-8 and IP-10 by human immunodeficiency virus type 1 tat in astrocytes

1 reference

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12 July 2018

Pronounced acute immunosuppression in vivo mediated by HIV Tat challenge

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12 July 2018

HIV-1 tat protein induces the production of interleukin-8 by human brain-derived endothelial cells

1 reference

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12 July 2018

HIV-1 tat molecular diversity and induction of TNF-alpha: implications for HIV-induced neurological disease

1 reference

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12 July 2018

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases

1 reference

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12 July 2018

Tat protein induces self-perpetuating permissivity for productive HIV-1 infection

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12 July 2018

Interleukin 10 is induced by recombinant HIV-1 Nef protein involving the calcium/calmodulin-dependent phosphodiesterase signal transduction pathway

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12 July 2018

The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.

1 reference

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12 July 2018

HIV-1 Tat protein as a potential AIDS vaccine

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12 July 2018

HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

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12 July 2018

Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation

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12 July 2018

Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells

1 reference

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12 July 2018

Effects of the Tat basic domain on human immunodeficiency virus type 1 transactivation, using chemically synthesized Tat protein and Tat peptides.

1 reference

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12 July 2018

The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein

1 reference

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12 July 2018

Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus

1 reference

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12 July 2018

IL-10 inhibits HIV-1 replication and is induced by tat.

1 reference

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12 July 2018

Human immunodeficiency virus 1 Tat binds to dipeptidyl aminopeptidase IV (CD26): a possible mechanism for Tat's immunosuppressive activity.

1 reference

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12 July 2018

The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence

1 reference

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12 July 2018

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.

1 reference

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12 July 2018

Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with the induction of other cytokines

1 reference

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12 July 2018

Kaposi's sarcoma among persons with AIDS: a sexually transmitted infection?

1 reference

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12 July 2018

Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1.

1 reference

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12 July 2018

Aids-Associated Malignant Lymphoma

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12 July 2018

Human immunodeficiency virus type 1 tat gene up-regulates interleukin 4 receptors on a human B-lymphoblastoid cell line.

1 reference

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12 July 2018

The role of monocyte/macrophages and cytokines in the pathogenesis of HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

12 July 2018

tat protein stimulates production of transforming growth factor-beta 1 by marrow macrophages: a potential mechanism for human immunodeficiency virus-1-induced hematopoietic suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

12 July 2018

Effects of the human immunodeficiency virus type 1 Tat protein on the expression of inflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

12 July 2018

HIV interferes with SOCS-1 and -3 expression levels driving immune activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

Human immunodeficiency virus type 1 clade B and C Tat differentially induce indoleamine 2,3-dioxygenase and serotonin in immature dendritic cells: Implications for neuroAIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 Vpr induces TLR4/MyD88-mediated IL-6 production and reactivates viral production from latency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 Tat is unconventionally secreted through the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 Tat protein induces IL-10 production in monocytes by classical and alternative NF-kappaB pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 Tat protein induces IL-10 production by an alternative TNF-alpha-independent pathway in monocytes: role of PKC-delta and p38 MAP kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 infection and HIV-1 Tat protein permit the survival and replication of a non-pathogenic trypanosomatid in macrophages through TGF-beta1 production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

Differentiation of monocytes into CD1a- dendritic cells correlates with disease progression in HIV-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

IL-10 regulation by HIV-Tat in primary human monocytic cells: involvement of calmodulin/calmodulin-dependent protein kinase-activated p38 MAPK and Sp-1 and CREB-1 transcription factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

Human immunodeficiency virus type 1 Tat activity in human neuronal cells: uptake and trans-activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

25 September 2018

HIV-1 Vpr inhibits the maturation and activation of macrophages and dendritic cells in vitro

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0129425

21 January 2018

Involvement of PKCα/β in TLR4 and TLR2 dependent activation of NF-κB

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0129425

21 January 2018

The role of cytokines in immune response to HIV

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4474861

15 November 2018

Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0129425

21 January 2018

The TLR7 agonist R848 alleviates allergic inflammation by targeting invariant NKT cells to produce IFN-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Tat suppresses gp120-specific T cell response in IL-10-dependent manner

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Tat inhibits human natural killer cell function by blocking L-type calcium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine profiles in a cohort of long-term survivors of transfusion-acquired HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunologic abnormalities in the acquired immunodeficiency syndrome (AIDS)

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infection with HIV is associated with elevated IL-6 levels and production

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocytes are target cells for IL-10 induction by HIV-1 Nef protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Tat protein induces TNF-alpha and IL-10 production by human macrophages: differential implication of PKC-betaII and -delta isozymes and MAP kinases ERK1/2 and p38

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated serum levels of IL-8 in patients with HIV infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[HIV-1 Tat induces TNF-alpha production by human monocytes: involvement of calcium and PKC pathways]

1 reference

https://pubmed.ncbi.nlm.nih.gov/26090662

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0129425

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090662%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

2015PLoSO..1029425B

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090662%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26090662%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

ResearchGate publication ID

0 references

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