(Q35670183)

9 August 2017

1 reference

title

Maximizing the potential of functional genomics (English)

1 reference

9 August 2017

1 reference

1 reference

Lars M Steinmetz

1

0 references

author name string

Ronald W Davis

series ordinal

2

1 reference

PubMed ID

14970821

9 August 2017

language of work or name

1 reference

1 March 2004

1 reference

9 August 2017

Nature Reviews Genetics

1 reference

9 August 2017

5

1 reference

9 August 2017

190-201

1 reference

9 August 2017

3

1 reference

https://scigraph.springernature.com/pub.10.1038/nrg1293

9 August 2017

0 references

cites work

Searching for genetic determinants in the new millennium

1 reference

Finding the molecular basis of quantitative traits: successes and pitfalls.

31 March 2020

1 reference

A vision for the future of genomics research

31 March 2020

1 reference

Initial sequencing and comparative analysis of the mouse genome

31 March 2020

1 reference

Sequencing and comparison of yeast species to identify genes and regulatory elements

31 March 2020

1 reference

Finding Functional Features in Saccharomyces Genomes by Phylogenetic Footprinting

31 March 2020

1 reference

Chemical genetics: ligand-based discovery of gene function

31 March 2020

1 reference

Functional profiling of the Saccharomyces cerevisiae genome

31 March 2020

1 reference

Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

31 March 2020

1 reference

Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy

31 March 2020

1 reference

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells

31 March 2020

1 reference

Gene targeting by homologous recombination in Drosophila

31 March 2020

1 reference

Production of gene-targeted sheep by nuclear transfer from cultured somatic cells

31 March 2020

1 reference

Widespread aneuploidy revealed by DNA microarray expression profiling.

31 March 2020

1 reference

Large-scale analysis of the yeast genome by transposon tagging and gene disruption

31 March 2020

1 reference

Genome-wide insertional mutagenesis of Arabidopsis thaliana

31 March 2020

1 reference

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

31 March 2020

1 reference

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

31 March 2020

1 reference

Heritable gene silencing in Drosophila using double-stranded RNA.

31 March 2020

1 reference

Effective targeted gene 'knockdown' in zebrafish

31 March 2020

1 reference

Specific interference with gene function by double-stranded RNA in early mouse development

31 March 2020

1 reference

Producing decaffeinated coffee plants

31 March 2020

1 reference

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

31 March 2020

1 reference

Expression profiling reveals off-target gene regulation by RNAi

31 March 2020

1 reference

Induction of an interferon response by RNAi vectors in mammalian cells

31 March 2020

1 reference

Activation of the interferon system by short-interfering RNAs

31 March 2020

1 reference

Functional discovery via a compendium of expression profiles

31 March 2020

1 reference

Drug target validation and identification of secondary drug target effects using DNA microarrays

31 March 2020

1 reference

Identifying regulatory networks by combinatorial analysis of promoter elements

31 March 2020

1 reference

Revealing modular organization in the yeast transcriptional network.

31 March 2020

1 reference

Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data

31 March 2020

1 reference

Dissecting the regulatory circuitry of a eukaryotic genome

31 March 2020

1 reference

Transcriptional regulatory networks in Saccharomyces cerevisiae

31 March 2020

1 reference

31 March 2020

Sillycon valley fever

1 reference

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

31 March 2020

1 reference

Complementary profiling of gene expression at the transcriptome and proteome levels in Saccharomyces cerevisiae

31 March 2020

1 reference

Protein pathway and complex clustering of correlated mRNA and protein expression analyses in Saccharomyces cerevisiae

31 March 2020

1 reference

Proteomics: the first decade and beyond

31 March 2020

1 reference

Global analysis of protein expression in yeast

31 March 2020

1 reference

Transcriptional response of Saccharomyces cerevisiae to DNA-damaging agents does not identify the genes that protect against these agents

31 March 2020

1 reference

Systematic screen for human disease genes in yeast

31 March 2020

1 reference

Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae

31 March 2020

1 reference

High-density arrays and insights into genome function.

31 March 2020

1 reference

Design issues for cDNA microarray experiments

31 March 2020

1 reference

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

31 March 2020

1 reference

Association analysis of NOTCH4 loci in schizophrenia using family and population-based controls

31 March 2020

1 reference

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

31 March 2020

1 reference

Multiplexed genotyping with sequence-tagged molecular inversion probes

31 March 2020

1 reference

A novel in vivo method to detect DNA sequence variation

31 March 2020

1 reference

Mismatch repair detection (MRD): high-throughput scanning for DNA variations

31 March 2020

1 reference

Association of genes to genetically inherited diseases using data mining

31 March 2020

1 reference

Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics

31 March 2020

1 reference

Combining mapping and arraying: An approach to candidate gene identification.

31 March 2020

1 reference

Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats.

31 March 2020

1 reference

Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo.

31 March 2020

1 reference

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

31 March 2020

1 reference

High-throughput classification of yeast mutants for functional genomics using metabolic footprinting.

31 March 2020

1 reference

Systematic genetic analysis with ordered arrays of yeast deletion mutants

31 March 2020

1 reference

DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray

31 March 2020

1 reference

Simultaneous identification of bacterial virulence genes by negative selection.

31 March 2020

1 reference

Application of high-density array-based signature-tagged mutagenesis to discover novel Yersinia virulence-associated genes

31 March 2020

1 reference

Discovery and analysis of inflammatory disease-related genes using cDNA microarrays

31 March 2020

1 reference

Distinctive gene expression patterns in human mammary epithelial cells and breast cancers

31 March 2020

1 reference

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

31 March 2020

1 reference

Variation in gene expression patterns in follicular lymphoma and the response to rituximab

31 March 2020

1 reference

Cluster analysis and display of genome-wide expression patterns

31 March 2020

1 reference

Systematic determination of genetic network architecture

31 March 2020

1 reference

Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters

31 March 2020

1 reference

A gene-coexpression network for global discovery of conserved genetic modules

31 March 2020

1 reference

Finding genes that underlie complex traits

31 March 2020

1 reference

Dissecting the architecture of a quantitative trait locus in yeast

31 March 2020

1 reference

Complexities in the genetic dissection of quantitative trait loci

31 March 2020

1 reference

Genetic architecture: dissecting the genetic basis of phenotypic variation

31 March 2020

1 reference

Quantitative trait loci in Drosophila

31 March 2020

1 reference

The human phenome project

31 March 2020

1 reference

Mapping and identification of essential gene functions on the X chromosome of Drosophila

31 March 2020

1 reference

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells

31 March 2020

1 reference

A silence that speaks volumes

31 March 2020

1 reference

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

31 March 2020

1 reference

Genomic profiling of drug sensitivities via induced haploinsufficiency.

31 March 2020

1 reference

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

31 March 2020

1 reference

Protein dispensability and rate of evolution

31 March 2020

1 reference

Evolutionary rate in the protein interaction network

31 March 2020

1 reference

Role of duplicate genes in genetic robustness against null mutations

31 March 2020

1 reference

Dosage sensitivity and the evolution of gene families in yeast

31 March 2020

1 reference

Light-directed, spatially addressable parallel chemical synthesis

31 March 2020

1 reference

High-density oligonucleotide arrays

31 March 2020

1 reference

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

31 March 2020

1 reference

A fiber-optic DNA biosensor microarray for the analysis of gene expression

31 March 2020

1 reference

Assessment of clone identity and sequence fidelity for 1189 IMAGE cDNA clones

31 March 2020

1 reference

31 March 2020

When the chips are down

1 reference

A genomic view of alternative splicing

31 March 2020

1 reference

Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays

31 March 2020

1 reference

Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21.

31 March 2020

1 reference

Direct allelic variation scanning of the yeast genome.

31 March 2020

1 reference

SNP genotyping with fluorescence polarization detection

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1293

1 reference

PubMed ID

14970821

Dimensions Publication ID

9 August 2017

0 references

1 reference

PubMed ID

14970821