(Q35670430)

9 August 2017

title

Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory (English)

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9 August 2017

1 reference

Jacqueline A Bonds

1

1 reference

9 August 2017

Yafit Kuttner-Hirshler

2

1 reference

9 August 2017

Nancy Bartolotti

3

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9 August 2017

Matthew K Tobin

4

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9 August 2017

Michael Pizzi

5

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9 August 2017

Robert Marr

6

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9 August 2017

Orly Lazarov

7

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9 August 2017

language of work or name

English

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publication date

22 June 2015

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9 August 2017

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9 August 2017

volume

10

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9 August 2017

issue

6

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9 August 2017

page(s)

e0131266

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Creative Commons Attribution 4.0 International

9 August 2017

copyright license

start time

22 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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12 July 2018

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Jagged1 is necessary for postnatal and adult neurogenesis in the dentate gyrus

12 July 2018

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Trans-dominant negative effects of pathogenic PSEN1 mutations on γ-secretase activity and Aβ production.

12 July 2018

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Notch1 signaling modulates neuronal progenitor activity in the subventricular zone in response to aging and focal ischemia

12 July 2018

1 reference

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Dynamics of hippocampal neurogenesis in adult humans

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation.

12 July 2018

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12 July 2018

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Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

12 July 2018

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Presenilin-1 regulates neural progenitor cell differentiation in the adult brain

12 July 2018

1 reference

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Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells

12 July 2018

1 reference

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12 July 2018

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A presenilin-1 mutation identified in familial Alzheimer disease with cotton wool plaques causes a nearly complete loss of gamma-secretase activity

12 July 2018

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Inhibition of notch signaling in human embryonic stem cell-derived neural stem cells delays G1/S phase transition and accelerates neuronal differentiation in vitro and in vivo.

12 July 2018

1 reference

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GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus

12 July 2018

1 reference

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Indirect regulation of presenilins in CREB-mediated transcription.

12 July 2018

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Noggin expands neural stem cells in the adult hippocampus

12 July 2018

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Wnt signalling regulates adult hippocampal neurogenesis

12 July 2018

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Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability

12 July 2018

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12 July 2018

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Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Presenilin 1 regulates beta-catenin-mediated transcription in a glycogen synthase kinase-3-independent fashion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Separation of presenilin function in amyloid beta-peptide generation and endoproteolysis of Notch

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Presenilin 1 facilitates the constitutive turnover of beta-catenin: differential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Dendritic pathology of granule cells in Alzheimer's disease is unrelated to neuritic plaques.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Canonical Wnt signaling is necessary for object recognition memory consolidation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Gamma-secretase gene mutations in familial acne inversa

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

The consolidation of object and context recognition memory involve different regions of the temporal lobe.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Loss of presenilin function causes Alzheimer's disease-like neurodegeneration in the mouse.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Notch signaling regulates neural precursor allocation and binary neuronal fate decisions in zebrafish

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Short-term and long-term survival of new neurons in the rat dentate gyrus

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4476567

Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26098332

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0131266

1 reference

9 August 2017

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9 August 2017

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