(Q35671251)

9 August 2017

title

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β. (English)

1 reference

9 August 2017

1 reference

16

1 reference

9 August 2017

Dominic De Nardo

4

0 references

Seth L Masters

Seth L Masters

17

0 references

Andrew W. Roberts

Andrew W Roberts

11

0 references

Dena Lyras

Dena Lyras

14

0 references

Benjamin T. Kile

Benjamin T Kile

15

0 references

Andrew M Lew

Andrew M Lew

13

0 references

Donald Metcalf

10

Donald Metcalf

1 reference

9 August 2017

12

Daniel L Kastner

1 reference

9 August 2017

2

Jae Jin Chae

1 reference

9 August 2017

3

Yong Hwan Park

1 reference

9 August 2017

8

Louise Cengia

1 reference

9 August 2017

Man Lyang Kim

1

1 reference

9 August 2017

Roslynn A Stirzaker

5

1 reference

9 August 2017

Hyun-Ja Ko

6

1 reference

9 August 2017

Hazel Tye

7

1 reference

9 August 2017

Ladina DiRago

9

1 reference

9 August 2017

language of work or name

English

0 references

publication date

25 May 2015

1 reference

Journal of Experimental Medicine

9 August 2017

published in

1 reference

9 August 2017

volume

212

1 reference

9 August 2017

issue

6

1 reference

9 August 2017

page(s)

927-938

1 reference

Actin polymerization as a key innate immune effector mechanism to control Salmonella infection

9 August 2017

cites work

1 reference

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Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasome

12 July 2018

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Monogenic autoinflammatory syndromes: state of the art on genetic, clinical, and therapeutic issues

12 July 2018

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Divergence of IL-1, IL-18, and cell death in NLRP3 inflammasomopathies

12 July 2018

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NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells

12 July 2018

1 reference

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Inflammasome-dependent pyroptosis and IL-18 protect against Burkholderia pseudomallei lung infection while IL-1β is deleterious

12 July 2018

1 reference

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Non-canonical inflammasome activation targets caspase-11

12 July 2018

1 reference

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Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice

12 July 2018

1 reference

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NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

12 July 2018

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Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

12 July 2018

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12 July 2018

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Caspase-1 activation via Rho GTPases: a common theme in mucosal infections?

12 July 2018

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Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)

12 July 2018

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IL-18 and skin inflammation

12 July 2018

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

12 July 2018

1 reference

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Pyrin and ASC co-localize to cellular sites that are rich in polymerizing actin

12 July 2018

1 reference

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Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages

12 July 2018

1 reference

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Active caspase-1 is a regulator of unconventional protein secretion

12 July 2018

1 reference

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Pyrin levels in human monocytes and monocyte-derived macrophages regulate IL-1beta processing and release

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

12 July 2018

1 reference

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Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization

12 July 2018

1 reference

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

12 July 2018

1 reference

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Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Gout-associated uric acid crystals activate the NALP3 inflammasome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

The biogenesis of platelets from megakaryocyte proplatelets

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Serum interleukin 17 and interleukin 18 levels in familial Mediterranean fever.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Actin-based motility of intracellular pathogens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Colchicine treatment in children with familial Mediterranean fever

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Defective NK cell activity and Th1 response in IL-18-deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Cloning of the cDNA for human IFN-gamma-inducing factor, expression in Escherichia coli, and studies on the biologic activities of the protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Cloning of a new cytokine that induces IFN-gamma production by T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

The granulocyte-macrophage colony-stimulating factors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Activating the NLRP3 inflammasome using the amyloidogenic peptide IAPP.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

Latrunculins--novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4451132

A Role for IL-18 in Neutrophil Activation

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20142384

Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20142384

Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

21 January 2018

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Crossref

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IL-1 receptor deficiency slows progression to diabetes in the NOD mouse

21 January 2018

1 reference

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Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate. An enzyme-histochemical study

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26008898

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26008898

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20142384

1 reference

9 August 2017

1 reference

9 August 2017

1 reference