(Q35676254)

9 August 2017

title

Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells (English)

1 reference

9 August 2017

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1 reference

Maria Perticone

6

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Francesco Andreozzi

object named as

Francesco Andreozzi

1

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Giorgio Sesti

object named as

Giorgio Sesti

9

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author name string

Emanuela Laratta

2

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9 August 2017

Cristina Procopio

3

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9 August 2017

Marta Letizia Hribal

4

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9 August 2017

Angela Sciacqua

5

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9 August 2017

Claudia Miele

7

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9 August 2017

Francesco Perticone

8

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9 August 2017

language of work or name

English

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publication date

22 January 2007

1 reference

Molecular and Cellular Biology

9 August 2017

published in

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9 August 2017

volume

27

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9 August 2017

issue

6

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9 August 2017

page(s)

2372-2383

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Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha

9 August 2017

cites work

1 reference

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Chronic interleukin-6 (IL-6) treatment increased IL-6 secretion and induced insulin resistance in adipocyte: prevention by rosiglitazone.

12 July 2018

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Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects

12 July 2018

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12 July 2018

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12 July 2018

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Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes.

12 July 2018

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Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

12 July 2018

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Interleukin-6 induces cellular insulin resistance in hepatocytes

12 July 2018

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12 July 2018

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C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus

12 July 2018

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Prognostic significance of endothelial dysfunction in hypertensive patients

12 July 2018

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Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells

12 July 2018

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Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179).

12 July 2018

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Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.

12 July 2018

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12 July 2018

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12 July 2018

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Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells

12 July 2018

1 reference

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The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

12 July 2018

1 reference

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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

12 July 2018

1 reference

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Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

12 July 2018

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12 July 2018

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Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase

12 July 2018

1 reference

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Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.

12 July 2018

1 reference

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Obesity/insulin resistance is associated with endothelial dysfunction. Implications for the syndrome of insulin resistance

12 July 2018

1 reference

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IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

12 July 2018

1 reference

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Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

12 July 2018

1 reference

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Diabetes and cardiovascular disease. The "common soil" hypothesis

12 July 2018

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The L-arginine-nitric oxide pathway

12 July 2018

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Biomarkers of endothelial dysfunction and risk of type 2 diabetes mellitus

12 July 2018

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Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells

25 September 2018

1 reference

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G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells

25 September 2018

1 reference

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Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice

25 September 2018

1 reference

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Endothelial function in health and disease: new insights into the genesis of cardiovascular disease

25 September 2018

1 reference

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Wortmannin inhibits insulin-stimulated activation of protein phosphatase 1 in rat cardiomyocytes

25 September 2018

1 reference

12 December 2020

Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjects with type 2 diabetes in association with insulin resistance

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12 December 2020

Elevated risk of cardiovascular disease prior to clinical diagnosis of type 2 diabetes

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12 December 2020

Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study

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12 December 2020

Identifiers

DOI

10.1128/MCB.01340-06

1 reference

9 August 2017

1 reference

9 August 2017

1 reference