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Ras, PI3K/Akt and senescence: Paradoxes provide clues for pancreatic cancer therapy.
scientific article published on September 2011
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
title
Ras, PI3K/Akt and senescence: Paradoxes provide clues for pancreatic cancer therapy
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
main subject
pancreatic cancer
1 reference
based on heuristic
inferred from title
author
Jennifer P. Morton
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
author name string
Alyssa L Kennedy
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
Peter D Adams
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
publication date
1 September 2011
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
published in
Small GTPases (journal)
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
volume
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
page(s)
264-267
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
cites work
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Healing and hurting: molecular mechanisms, functions, and pathologies of cellular senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF-1/PI3K/Akt signaling pathway in pancreatic cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Regulation of pancreas plasticity and malignant transformation by Akt signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Combinatorial patterns of somatic gene mutations in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Cancer statistics, 2007
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Mechanisms of disease: PI3K/AKT signaling in gastrointestinal cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
BRAFE600-associated senescence-like cell cycle arrest of human naevi
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Tumour biology: senescence in premalignant tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
27 July 2018
Activation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Modeling pancreatic cancer in vivo: from xenograft and carcinogen-induced systems to genetically engineered mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Pten constrains centroacinar cell expansion and malignant transformation in the pancreas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Colorectal cancer: mutations in a signalling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Oncogene-induced senescence as an initial barrier in lymphoma development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Phosphorylated Akt/PKB controls cell growth and apoptosis in intraductal papillary-mucinous tumor and invasive ductal adenocarcinoma of the pancreas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Progression model for pancreatic cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Pancreatic cancer: a report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265817
retrieved
25 September 2018
Gone but not forgotten
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.4161%2FSGTP.2.5.17367
retrieved
21 January 2018
Amplification and overexpression of the AKT2 oncogene in a subset of human pancreatic ductal adenocarcinomas
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22292129
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/SGTP.2.5.17367
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PMC publication ID
3265817
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
PubMed publication ID
22292129
1 reference
stated in
Europe PubMed Central
PMC publication ID
3265817
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22292129%20AND%20SRC:MED&resulttype=core&format=json
retrieved
21 January 2020
ResearchGate publication ID
221793406
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