(Q40507359)

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The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 September 2017

The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-kappaB and c-Myc in pancreatic cancer cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

pancreatic cancer

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

James Lewis Abbruzzese

5

object named as

James L Abbruzzese

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

4

object named as

Donghui Li

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

3

object named as

Jijiang Zhu

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Shrikanth A G Reddy

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object named as

Shrikanth A G Reddy

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Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Takayuki Asano

1

1 reference

Europe PubMed Central

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21 September 2017

Yixin Yao

2

1 reference

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21 September 2017

language of work or name

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publication date

1 November 2004

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Europe PubMed Central

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21 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

23

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21 September 2017

53

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21 September 2017

8571-8580

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Function of the c-Myc oncogenic transcription factor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Myc and Mad bHLHZ domains possess identical DNA-binding specificities but only partially overlapping functions in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Tumor suppressor MMAC/PTEN inhibits cytokine-induced NFkappaB activation without interfering with the IkappaB degradation pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Linking molecular therapeutics to molecular diagnostics: inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Phosphatidylinositol 3-kinase in interleukin 1 signaling. Physical interaction with the interleukin 1 receptor and requirement in NFkappaB and AP-1 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Isolation of transforming murine leukemia viruses from mice with a high incidence of spontaneous lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

21 January 2018

Role of NF-kappaB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Increasing complexity of Ras signaling.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

The multiple roles of PTEN in tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

PTEN transcriptionally modulates c-myc gene expression in human breast carcinoma cells and is involved in cell growth regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Pancreatic cancer cell proliferation is phosphatidylinositol 3-kinase dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphatidylinositol-3-OH kinase as a direct target of Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of Akt in growth and survival of PANC-1 pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207902

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1207902

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

ResearchGate publication ID

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