(Q35709954)

English

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice

scientific article published on 28 November 2011

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice (English)

1 reference

Europe PubMed Central

9 August 2017

1 reference

based on heuristic

inferred from title

insulin resistance

1 reference

based on heuristic

inferred from title

Gerald I. Shulman

10

object named as

Gerald I Shulman

1 reference

Europe PubMed Central

9 August 2017

Varman T Samuel

8

object named as

Varman T Samuel

1 reference

Europe PubMed Central

9 August 2017

Michael J. Jurczak

1

object named as

Michael J Jurczak

1 reference

Europe PubMed Central

9 August 2017

6

object named as

Blas A Guigni

1 reference

Europe PubMed Central

9 August 2017

7

object named as

Mario Kahn

1 reference

Europe PubMed Central

9 August 2017

François R Jornayvaz

3

object named as

Francois R Jornayvaz

1 reference

Europe PubMed Central

9 August 2017

Andreas Birkenfeld

5

object named as

Andreas L Birkenfeld

1 reference

Europe PubMed Central

9 August 2017

2

object named as

Ann-Hwee Lee

1 reference

Europe PubMed Central

9 August 2017

Laurie Glimcher

9

object named as

Laurie H Glimcher

1 reference

Europe PubMed Central

9 August 2017

author name string

Hui-Young Lee

4

1 reference

Europe PubMed Central

9 August 2017

language of work or name

0 references

publication date

28 November 2011

1 reference

Europe PubMed Central

9 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

9 August 2017

287

1 reference

Europe PubMed Central

9 August 2017

2558-2567

1 reference

Europe PubMed Central

9 August 2017

4

1 reference

Europe PubMed Central

9 August 2017

Ceramides as modulators of cellular and whole-body metabolism

1 reference

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Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

1 reference

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SGLT2 deletion improves glucose homeostasis and preserves pancreatic beta-cell function

1 reference

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Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

1 reference

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Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

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Targeted expression of catalase to mitochondria prevents age-associated reductions in mitochondrial function and insulin resistance.

1 reference

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A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain

1 reference

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Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice

1 reference

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Pathogenesis of fasting and postprandial hyperglycemia in type 2 diabetes: implications for therapy

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Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress

1 reference

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Lipid-induced insulin resistance: unravelling the mechanism

1 reference

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Diacylglycerol-mediated insulin resistance

1 reference

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JNK1 and IKKbeta: molecular links between obesity and metabolic dysfunction

1 reference

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

1 reference

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Irs1 serine 307 promotes insulin sensitivity in mice

1 reference

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12 July 2018

Prevention of steatosis by hepatic JNK1

1 reference

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12 July 2018

Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance

1 reference

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12 July 2018

Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance

1 reference

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Imatinib mesylate reduces endoplasmic reticulum stress and induces remission of diabetes in db/db mice

1 reference

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12 July 2018

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

1 reference

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Acid Sphingomyelinase Deficiency Prevents Diet-induced Hepatic Triacylglycerol Accumulation and Hyperglycemia in Mice

1 reference

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12 July 2018

A stress signaling pathway in adipose tissue regulates hepatic insulin resistance

1 reference

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Regulation of hepatic lipogenesis by the transcription factor XBP1

1 reference

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Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice

1 reference

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Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance

1 reference

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12 July 2018

Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

1 reference

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Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance.

1 reference

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The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome

1 reference

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XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

1 reference

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Suppression of diacylglycerol acyltransferase-2 (DGAT2), but not DGAT1, with antisense oligonucleotides reverses diet-induced hepatic steatosis and insulin resistance

1 reference

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Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease

1 reference

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Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

1 reference

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Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

1 reference

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Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

1 reference

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The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.

1 reference

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1 reference

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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

1 reference

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1 reference

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Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

1 reference

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Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease.

1 reference

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1 reference

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A central role for JNK in obesity and insulin resistance

1 reference

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12 July 2018

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268415

12 July 2018

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

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Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

1 reference

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Cellular mechanisms of insulin resistance

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12 July 2018

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

1 reference

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12 July 2018

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

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Mice lacking MAP kinase phosphatase-1 have enhanced MAP kinase activity and resistance to diet-induced obesity.

1 reference

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Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

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Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

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1 reference

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25 September 2018

Identifiers

10.1074/JBC.M111.316760

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

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