(Q35712200)

English

Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p

scientific article published on 7 December 2011

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scholarly article

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18 January 2020

Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p (English)

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18 January 2020

Schizosaccharomyces pombe

object named as

Schizosaccharomyces pombe

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based on heuristic

inferred from title

5

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18 January 2020

Richard J. Maraia

6

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18 January 2020

author name string

Vera Cherkasova

1

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18 January 2020

Luis Lopez Maury

2

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18 January 2020

Dagmar Bacikova

3

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18 January 2020

Kevin Pridham

4

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18 January 2020

publication date

7 December 2011

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18 January 2020

Molecular Biology of the Cell

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18 January 2020

23

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18 January 2020

3

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18 January 2020

480-491

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18 January 2020

Maf1 protein, repressor of RNA polymerase III, indirectly affects tRNA processing

1 reference

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3' processing of eukaryotic precursor tRNAs.

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The ins and outs of nuclear re-export of retrogradely transported tRNAs in Saccharomyces cerevisiae

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Comparative whole genome sequencing reveals phenotypic tRNA gene duplication in spontaneous Schizosaccharomyces pombe La mutants.

1 reference

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The roles of stress-activated Sty1 and Gcn2 kinases and of the protooncoprotein homologue Int6/eIF3e in responses to endogenous oxidative stress during histidine starvation.

1 reference

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tRNA biology charges to the front

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Conserved and divergent features of the structure and function of La and La-related proteins (LARPs)

1 reference

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Structures of the tRNA export factor in the nuclear and cytosolic states

1 reference

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Mapping epigenetic mutations in fission yeast using whole-genome next-generation sequencing

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Rex1p deficiency leads to accumulation of precursor initiator tRNAMet and polyadenylation of substrate RNAs in Saccharomyces cerevisiae

1 reference

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Akt phosphorylation of La regulates specific mRNA translation in glial progenitors

1 reference

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27 July 2018

Competition between the Rex1 exonuclease and the La protein affects both Trf4p-mediated RNA quality control and pre-tRNA maturation

1 reference

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Transcription factors Pcr1 and Atf1 have distinct roles in stress- and Sty1-dependent gene regulation

1 reference

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A decade of surprises for tRNA nuclear-cytoplasmic dynamics

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Cytoplasmic splicing of tRNA in Saccharomyces cerevisiae

1 reference

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27 July 2018

Conservation of a masked nuclear export activity of La proteins and its effects on tRNA maturation

1 reference

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Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast

1 reference

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Fission yeast Tor2 promotes cell growth and represses cell differentiation.

1 reference

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Ammonia-specific regulation of Gln3 localization in Saccharomyces cerevisiae by protein kinase Npr1.

1 reference

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The La protein functions redundantly with tRNA modification enzymes to ensure tRNA structural stability

1 reference

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TOR signaling in growth and metabolism

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Cellular dynamics of small RNAs

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Mapping pathways and phenotypes by systematic gene overexpression

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27 July 2018

The multifunctional RNA-binding protein La is required for mouse development and for the establishment of embryonic stem cells

1 reference

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27 July 2018

Structural basis for recognition and sequestration of UUU(OH) 3' temini of nascent RNA polymerase III transcripts by La, a rheumatic disease autoantigen

1 reference

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27 July 2018

Human La is found at RNA polymerase III-transcribed genes in vivo

1 reference

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27 July 2018

Translational regulation of GCN4 and the general amino acid control of yeast

1 reference

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Conservation and evolvability in regulatory networks: the evolution of ribosomal regulation in yeast

1 reference

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27 July 2018

La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro

1 reference

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27 July 2018

Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation

1 reference

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27 July 2018

Roles of histone acetylation and chromatin remodeling factor in a meiotic recombination hotspot.

1 reference

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27 July 2018

A La protein requirement for efficient pre-tRNA folding.

1 reference

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27 July 2018

Differential phosphorylation and subcellular localization of La RNPs associated with precursor tRNAs and translation-related mRNAs.

1 reference

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27 July 2018

Possibility of cytoplasmic pre-tRNA splicing: the yeast tRNA splicing endonuclease mainly localizes on the mitochondria

1 reference

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Whole-genome microarrays of fission yeast: characteristics, accuracy, reproducibility, and processing of array data

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27 July 2018

Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism

1 reference

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27 July 2018

La protein is associated with terminal oligopyrimidine mRNAs in actively translating polysomes

1 reference

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27 July 2018

Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2.

1 reference

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27 July 2018

BCR/ABL activates mdm2 mRNA translation via the La antigen

1 reference

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27 July 2018

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains

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27 July 2018

Role of the Tsc1-Tsc2 complex in signaling and transport across the cell membrane in the fission yeast Schizosaccharomyces pombe

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27 July 2018

Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs

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27 July 2018

1 reference

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27 July 2018

La protein and the trafficking of nascent RNA polymerase iii transcripts

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27 July 2018

Control of transfer RNA maturation by phosphorylation of the human La antigen on serine 366

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27 July 2018

Review: transport of tRNA out of the nucleus-direct channeling to the ribosome?

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27 July 2018

Defects in tRNA processing and nuclear export induce GCN4 translation independently of phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2

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27 July 2018

GCD14p, a repressor of GCN4 translation, cooperates with Gcd10p and Lhp1p in the maturation of initiator methionyl-tRNA in Saccharomyces cerevisiae

1 reference

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27 July 2018

Coordination of tRNA nuclear export with processing of tRNA.

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27 July 2018

A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts

1 reference

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27 July 2018

The role of exportin-t in selective nuclear export of mature tRNAs

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27 July 2018

Yeast Los1p has properties of an exportin-like nucleocytoplasmic transport factor for tRNA

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27 July 2018

Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombe

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27 July 2018

Transcription factor Mts1/Mts2 (Atf1/Pcr1, Gad7/Pcr1) activates the M26 meiotic recombination hotspot in Schizosaccharomyces pombe

1 reference

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27 July 2018

Rapamycin specifically interferes with the developmental response of fission yeast to starvation

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27 July 2018

A recombinationally repressed region between mat2 and mat3 loci shares homology to centromeric repeats and regulates directionality of mating-type switching in fission yeast.

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27 July 2018

The yeast La protein is required for the 3' endonucleolytic cleavage that matures tRNA precursors

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27 July 2018

Schizosaccharomyces pombe gad7+ encodes a phosphoprotein with a bZIP domain, which is required for proper G1 arrest and gene expression under nitrogen starvation

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27 July 2018

Fission yeast genes which disrupt mitotic chromosome segregation when overexpressed

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27 July 2018

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27 July 2018

Schizosaccharomyces pombe atf1+ encodes a transcription factor required for sexual development and entry into stationary phase

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27 July 2018

Comparison of Schizosaccharomyces pombe expression systems

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27 July 2018

Multicopy tRNA genes functionally suppress mutations in yeast eIF-2 alpha kinase GCN2: evidence for separate pathways coupling GCN4 expression to unchanged tRNA

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27 July 2018

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1 reference

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27 July 2018

Determinants of half-site spacing preferences that distinguish AP-1 and ATF/CREB bZIP domains

1 reference

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27 July 2018

Homology between the DNA-binding domain of the GCN4 regulatory protein of yeast and the carboxyl-terminal region of a protein coded for by the oncogene jun.

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27 July 2018

Fos and Jun: the AP-1 connection

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27 July 2018

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27 July 2018

Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing

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27 July 2018

Expression of the SV40 promoter in fission yeast: identification and characterization of an AP-1-like factor

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27 July 2018

Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3)

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Evolution of the TSC1/TSC2-TOR signaling pathway.

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25 September 2018

tRNAs: cellular barcodes for amino acids.

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25 September 2018

Precursor-product discrimination by La protein during tRNA metabolism.

1 reference

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25 September 2018

Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy

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25 September 2018

S. pombe strain maintenance and media

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25 September 2018

Impaired tRNA nuclear export links DNA damage and cell-cycle checkpoint

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25 September 2018

tRNA traffic meets a cell-cycle checkpoint.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

New drug-resistant cassettes for gene disruption and epitope tagging in Schizosaccharomyces pombe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

Tsc1+ and tsc2+ regulate arginine uptake and metabolism in Schizosaccharomyces pombe

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

Fission yeast tor1 functions in response to various stresses including nitrogen starvation, high osmolarity, and high temperature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

TOR modulates GCN4-dependent expression of genes turned on by nitrogen limitation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

The essential Gcd10p-Gcd14p nuclear complex is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

Proofreading and aminoacylation of tRNAs before export from the nucleus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

The La protein in Schizosaccharomyces pombe: a conserved yet dispensable phosphoprotein that functions in tRNA maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

25 September 2018

The pub1 E3 ubiquitin ligase negatively regulates leucine uptake in response to NH(4)(+) in fission yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268726

15 November 2018

Order and intracellular location of the events involved in the maturation of a spliced tRNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of intervening sequences: a new yeast mutant which fails to excise intervening sequences from precursor tRNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of L-lysine in the fission yeast Schizosaccharomyces pombe

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast GCN4 as a probe for oncogenesis by AP-1 transcription factors: transcriptional activation through AP-1 sites is not sufficient for cellular transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separate RNA-binding surfaces on the multifunctional La protein mediate distinguishable activities in tRNA maturation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Schizosaccharomyces pombe Atf1 protein levels by Sty1-mediated phosphorylation and heterodimerization with Pcr1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160596

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E11-08-0732

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22160596%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22160596%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22160596%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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