(Q35718513)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

review article

1 reference

title

Chemical structures of inducers of nicotinamide quinone oxidoreductase 1 (NQO1) (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

Jed W Fahey

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

language of work or name

English

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publication date

1 January 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

published in

Methods in Enzymology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

volume

382

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

423-448

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

INDUCED PROTECTION OF ADRENAL CORTEX AGAINST 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE. INFLUENCE OF ETHIONINE. INDUCTION OF MENADIONE REDUCTASE. INCORPORATION OF THYMIDINE-H3.

26 December 2019

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7 January 2021

AROMATIC AZO DERIVATIVES PREVENTING MAMMARY CANCER AND ADRENAL INJURY FROM 7,12-DIMETHYLBENZ(a)ANTHRACENE

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7 January 2021

Increase of NAD(P)H:quinone reductase by dietary antioxidants: possible role in protection against carcinogenesis and toxicity

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7 January 2021

Mechanisms of induction of enzymes that protect against chemical carcinogenesis

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7 January 2021

Chemoprotection against cancer by phase 2 enzyme induction

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7 January 2021

Chemoprevention by inducers of carcinogen detoxication enzymes

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7 January 2021

Chemoprotection against cancer by induction of phase 2 enzymes

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7 January 2021

Role of nicotinamide quinone oxidoreductase 1 (NQO1) in protection against toxicity of electrophiles and reactive oxygen intermediates

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7 January 2021

Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: A screening assay for anticarcinogenic enzyme inducers

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7 January 2021

Rapid detection of inducers of enzymes that protect against carcinogens

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7 January 2021

Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens

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7 January 2021

The "Prochaska" microtiter plate bioassay for inducers of NQO1.

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7 January 2021

Specificity of induction of cancer protective enzymes by analogues of tert-butyl-4-hydroxyanisole (BHA)

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7 January 2021

On the mechanisms of induction of cancer-protective enzymes: a unifying proposal

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7 January 2021

Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis

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7 January 2021

Elevation of quinone reductase activity by anticarcinogenic antioxidants

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7 January 2021

Enhancement of epoxide hydrolase activity in hepatic microsomes of mice given heterocyclic compounds

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7 January 2021

Butylated hydroxytoluene (BHT)-mediated increases in NAD(P)H-quinone oxidoreductase (QR) in mouse lung: evidence for the alveolar type II cell as a site of QR activity

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7 January 2021

Chemoprotective and hepatic enzyme induction properties of indole and indenoindole antioxidants in rats

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7 January 2021

Low doses of diallyl disulfide, a compound derived from garlic, increase tissue activities of quinone reductase and glutathione transferase in the gastrointestinal tract of the rat

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7 January 2021

Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: a model system for the study of anticarcinogens

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7 January 2021

Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: correlation of potencies as phase 2 enzyme inducers and radical scavengers

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7 January 2021

The electrophile counterattack response: protection against neoplasia and toxicity.

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7 January 2021

The potency of inducers of NAD(P)H:(quinone-acceptor) oxidoreductase parallels their efficiency as substrates for glutathione transferases. Structural and electronic correlations

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7 January 2021

Modifying effects of ferulic acid on azoxymethane-induced colon carcinogenesis in F344 rats

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7 January 2021

Dietary Supplementation of Curcumin Enhances Antioxidant and Phase II Metabolizing Enzymes in ddY Male Mice: Possible Role in Protection against Chemical Carcinogenesis and Toxicity

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7 January 2021

Curcumin and especially tetrahydrocurcumin ameliorate oxidative stress-induced renal injury in mice

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7 January 2021

Effect of the beta-diketones diferuloylmethane (curcumin) and dibenzoylmethane on rat mammary DNA adducts and tumors induced by 7,12-dimethylbenz[a]anthracene

1 reference

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7 January 2021

Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes

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7 January 2021

Mechanism-based in vitro screening of potential cancer chemopreventive agents

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7 January 2021

Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase.

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7 January 2021

Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

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7 January 2021

Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.

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7 January 2021

Protective action of cardiac DT-diaphorase against menadione toxicity in guinea pig isolated atria

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7 January 2021

Protection against cancer by plant phenylpropenoids: induction of mammalian anticarcinogenic enzymes

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7 January 2021

Dietary quercetin glycosides: antioxidant activity and induction of the anticarcinogenic phase II marker enzyme quinone reductase in Hepalclc7 cells

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7 January 2021

Induction of the anticarcinogenic marker enzyme, quinone reductase, in murine hepatoma cells in vitro by flavonoids

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7 January 2021

Induction of human NAD(P)H:quinone oxidoreductase (NQO1) gene expression by the flavonol quercetin

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7 January 2021

Pinostrobin from honey and Thai ginger (Boesenbergia pandurata): a potent flavonoid inducer of mammalian phase 2 chemoprotective and antioxidant enzymes

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7 January 2021

Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats

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7 January 2021

Chemopreventive effect of dietary flavonoid morin on chemically induced rat tongue carcinogenesis

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7 January 2021

Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay.

1 reference

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7 January 2021

Activity-guided isolation of constituents of Renealmia nicolaioides with the potential to induce the phase II enzyme quinone reductase.

1 reference

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7 January 2021

Tissue distribution of silibinin, the major active constituent of silymarin, in mice and its association with enhancement of phase II enzymes: implications in cancer chemoprevention.

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7 January 2021

Activity-Guided Isolation of Constituents ofTephrosia purpureawith the Potential to Induce the Phase II Enzyme, Quinone Reductase

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7 January 2021

Minor withanolides from Physalis philadelphica: structures, quinone reductase induction activities, and liquid chromatography (LC)-MS-MS investigation as artifacts.

1 reference

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7 January 2021

Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity

1 reference

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7 January 2021

Induction of quinone reductase by withanolides.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

Characterization of flavonoids as monofunctional or bifunctional inducers of quinone reductase in murine hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes

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7 January 2021

Role of glutathione in the accumulation of anticarcinogenic isothiocyanates and their glutathione conjugates by murine hepatoma cells.

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7 January 2021

Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

High cellular accumulation of sulphoraphane, a dietary anticarcinogen, is followed by rapid transporter-mediated export as a glutathione conjugate

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

Total intracellular accumulation levels of dietary isothiocyanates determine their activity in elevation of cellular glutathione and induction of Phase 2 detoxification enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway

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7 January 2021

Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice.

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7 January 2021

alpha-Naphthylisothiocyanate induced alterations in hepatic drug metabolizing enzymes and liver morphology: implications concerning anticarcinogenesis

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7 January 2021

?-naphthylisothiocyanate-induced alterations in hepatic drug metabolism and liver morphology

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7 January 2021

1,2-Dithiol-3-thione analogs: effects on NAD(P)H:quinone reductase and glutathione levels in murine hepatoma cells.

1 reference

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7 January 2021

Induction of NAD(P)H:quinone reductase in human peripheral blood lymphocytes

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7 January 2021

Biochemical effects of dithiolthiones

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7 January 2021

Oxathiolene oxides: a novel family of compounds that induce ferritin, glutathione S-transferase, and other proteins of the phase II response

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7 January 2021

Chemoprotection by organosulfur inducers of phase 2 enzymes: dithiolethiones and dithiins

1 reference

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7 January 2021

Effects of organosulfur compounds from garlic and onions on benzo[a]pyrene-induced neoplasia and glutathione S-transferase activity in the mouse.

1 reference

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7 January 2021

Differential induction of NAD(P)H:quinone oxidoreductase by anti-carcinogenic organosulfides from garlic.

1 reference

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7 January 2021

Modulation of phase II enzymes by organosulfur compounds from allium vegetables in rat tissues

1 reference

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7 January 2021

Antimutagenic activity of organosulfur compounds from Allium is associated with phase II enzyme induction

1 reference

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7 January 2021

Relative activities of organosulfur compounds derived from onions and garlic in increasing tissue activities of quinone reductase and glutathione transferase in rat tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

Comparative effects of mono-, di-, tri-, and tetrasulfides derived from plants of the Allium family: redox cycling in vitro and hemolytic activity and Phase 2 enzyme induction in vivo

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7 January 2021

British anti-lewisite; arsenic derivatives of thiol proteins

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7 January 2021

British anti-lewisite; dithiol compounds as antidotes for arsenic

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7 January 2021

British anti-lewisite; arsenic and thiol excretion in animals after treatment of lewisite burns

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7 January 2021

Mechanisms of inhibition of chemical toxicity and carcinogenesis by diallyl sulfide (DAS) and related compounds from garlic

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7 January 2021

Chemical and molecular regulation of enzymes that detoxify carcinogens

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7 January 2021

The neuroprotective antioxidant alpha-lipoic acid induces detoxication enzymes in cultured astroglial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

In vitro effect of mercury on aryl hydrocarbon hydroxylase, quinone reductase, catecholamine-O-methyltransferase and glucose-6-phosphate dehydrogenase activities in term human placenta.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

In vitro effect of mercury on enzyme activities and its accumulation in the first-trimester human placenta

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https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

Effect of cadmium on some enzyme activities in first-trimester human placentae

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2982023-8

7 January 2021

Effects of triethyl lead administration on the expression of glutathione S-transferase isoenzymes and quinone reductase in rat kidney and liver

1 reference

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7 January 2021

Mercurials and Dimercaptans: Synergism in the Induction of Chemoprotective Enzymes

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7 January 2021

Dose-response effects of lycopene on selected drug-metabolizing and antioxidant enzymes in the rat

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7 January 2021

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

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7 January 2021

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

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7 January 2021

Distribution of enzymes that catalyse reactions of glutathione with alpha beta-unsaturated compounds

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7 January 2021

10.1016/S0076-6879(04)82023-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15047115%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference