(Q35719890)

9 August 2017

title

Reactive nitrogen species in acetaminophen-induced mitochondrial damage and toxicity in mouse hepatocytes (English)

1 reference

9 August 2017

Angela S Burke

1

1 reference

9 August 2017

Lee Ann MacMillan-Crow

series ordinal

2

1 reference

9 August 2017

Jack A Hinson

series ordinal

3

1 reference

9 August 2017

publication date

1 July 2010

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Chemical Research in Toxicology

9 August 2017

published in

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9 August 2017

volume

23

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9 August 2017

issue

7

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9 August 2017

page(s)

1286-1292

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Mechanisms of acetaminophen-induced liver necrosis

9 August 2017

cites work

1 reference

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Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes

12 July 2018

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Acetaminophen-induced hepatotoxicity

12 July 2018

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12 July 2018

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Distribution of nitric oxide synthase in normal and cirrhotic human liver

12 July 2018

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Mechanisms of hepatotoxicity

12 July 2018

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Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

12 July 2018

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12 July 2018

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The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

12 July 2018

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Identification of the hepatic protein targets of reactive metabolites of acetaminophen in vivo in mice using two-dimensional gel electrophoresis and mass spectrometry

12 July 2018

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Nitrotyrosine-protein adducts in hepatic centrilobular areas following toxic doses of acetaminophen in mice

12 July 2018

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12 July 2018

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Protection against peroxynitrite dependent tyrosine nitration and alpha 1-antiproteinase inactivation by some anti-inflammatory drugs and by the antibiotic tetracycline

12 July 2018

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12 July 2018

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The inhibition of the constitutive and inducible nitric oxide synthase isoforms by indazole agents

12 July 2018

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N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

12 July 2018

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Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione

12 July 2018

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Reversal of acetaminophen toxicity in isolated hamster hepatocytes by dithiothreitol.

12 July 2018

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Mitochondrial dysfunction in paracetamol hepatotoxicity: in vitro studies in isolated mouse hepatocytes

12 July 2018

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Mechanisms of chloroform-induced hepatotoxicity: oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes.

12 July 2018

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Induction of the nuclear factor HIF-1alpha in acetaminophen toxicity: evidence for oxidative stress

25 September 2018

1 reference

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Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Mechanisms of acetaminophen-induced hepatotoxicity: role of oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Effect of inhibitors of nitric oxide synthase on acetaminophen-induced hepatotoxicity in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Acetaminophen-induced hepatotoxicity in mice lacking inducible nitric oxide synthase activity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide

25 September 2018

1 reference

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Purification and characterization of a nitric-oxide synthase from rat liver mitochondria

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

Intracellular calcium disruption as a secondary event in acetaminophen-induced hepatotoxicity.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269780

New aspects in the reaction mechanism of phenol with peroxynitrite: the role of phenoxy radicals

25 September 2018

1 reference

12 December 2020

Nitric oxide synthase activity in mitochondria

1 reference

12 December 2020

Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: implications for intracellular measurement of reactive nitrogen and oxygen species

1 reference

12 December 2020

On the selectivity of 7-nitroindazole as an inhibitor of neuronal nitric oxide synthase

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12 December 2020

Western blot analysis for nitrotyrosine protein adducts in livers of saline-treated and acetaminophen-treated mice

1 reference

12 December 2020

Nitrating reactive nitric oxygen species transform acetaminophen to 3-nitroacetaminophen

1 reference

12 December 2020

Galactosamine decreases nitric oxide formation in cultured rat hepatocytes: mechanism of suppression

1 reference

12 December 2020

Contribution of increased mitochondrial free Ca2+ to the mitochondrial permeability transition induced by tert-butylhydroperoxide in rat hepatocytes

1 reference

12 December 2020

Protein and nonprotein cysteinyl thiol modification by N-acetyl-p-benzoquinone imine via a novel ipso adduct

1 reference

12 December 2020

Freshly isolated hepatocytes as a model for studying the toxicity of paracetamol

1 reference

12 December 2020

Immunochemical localization of inducible nitric oxide synthase in endotoxin-treated rats

1 reference

12 December 2020

Effects of N-acetylcysteine and dithiothreitol on glutathione and protein thiol replenishment during acetaminophen-induced toxicity in isolated mouse hepatocytes

1 reference

12 December 2020

Identifiers

DOI

10.1021/TX1001755

1 reference

9 August 2017

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9 August 2017

1 reference