(Q35719892)

9 August 2017

title

TALE-mediated epigenetic suppression of CDKN2A increases replication in human fibroblasts (English)

1 reference

9 August 2017

Diana L Bernstein

1

1 reference

9 August 2017

John E Le Lay

series ordinal

2

1 reference

9 August 2017

Elena G Ruano

series ordinal

3

1 reference

9 August 2017

Klaus H Kaestner

series ordinal

4

1 reference

9 August 2017

language of work or name

English

0 references

publication date

13 April 2015

1 reference

Journal of Clinical Investigation

9 August 2017

published in

1 reference

9 August 2017

volume

125

1 reference

9 August 2017

issue

5

1 reference

9 August 2017

page(s)

1998-2006

1 reference

Use of epigenetic drugs in disease: an overview

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Ageing as developmental decay: insights from p16(INK4a.).

12 July 2018

1 reference

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DNA methylation is required for the control of stem cell differentiation in the small intestine

12 July 2018

1 reference

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CRISPR-Cas systems for editing, regulating and targeting genomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Tumor suppressor p16INK4A is necessary for survival of cervical carcinoma cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Locus-specific editing of histone modifications at endogenous enhancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Optimization of scarless human stem cell genome editing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

DNA methylation dynamics in health and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Review: a meta-analysis of GWAS and age-associated diseases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Functions of DNA methylation: islands, start sites, gene bodies and beyond

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

A transcription activator-like effector toolbox for genome engineering

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

TAL effectors: customizable proteins for DNA targeting

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Regulation of selected genome loci using de novo-engineered transcription activator-like effector (TALE)-type transcription factors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

BS Seeker: precise mapping for bisulfite sequencing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Up-regulation of expression and lack of 5' CpG island hypermethylation of p16 INK4a in HPV-positive cervical carcinomas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

p16INK4a induces an age-dependent decline in islet regenerative potential

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

The human genome browser at UCSC

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463192

Epigenomic networking in drug development: from pathogenic mechanisms to pharmacogenomics

12 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25866970

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25866970

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI77321

1 reference

9 August 2017

1 reference

9 August 2017

1 reference