(Q35729391)

English

Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways.

scientific article published on 5 December 2011

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

Oncogene mutation profiling of pediatric solid tumors reveals significant subsets of embryonal rhabdomyosarcoma and neuroblastoma with mutated genes in growth signaling pathways. (English)

1 reference

Europe PubMed Central

9 August 2017

0 references

9

Marc Ladanyi

1 reference

Europe PubMed Central

9 August 2017

author name string

Neerav Shukla

1

1 reference

Europe PubMed Central

9 August 2017

Nabahet Ameur

2

1 reference

Europe PubMed Central

9 August 2017

Ismail Yilmaz

3

1 reference

Europe PubMed Central

9 August 2017

Khedoudja Nafa

4

1 reference

Europe PubMed Central

9 August 2017

Chyau-Yueh Lau

5

1 reference

Europe PubMed Central

9 August 2017

Angela Marchetti

6

1 reference

Europe PubMed Central

9 August 2017

Laetitia Borsu

7

1 reference

Europe PubMed Central

9 August 2017

Frederic G Barr

8

1 reference

Europe PubMed Central

9 August 2017

language of work or name

0 references

publication date

5 December 2011

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Europe PubMed Central

9 August 2017

Clinical Cancer Research

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Europe PubMed Central

9 August 2017

18

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Europe PubMed Central

9 August 2017

748-757

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Europe PubMed Central

9 August 2017

3

1 reference

Europe PubMed Central

9 August 2017

IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours.

1 reference

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12 July 2018

Targeting phosphatidylinositol 3 kinase (PI3K)-Akt beyond rapalogs.

1 reference

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12 July 2018

GSK1120212 (JTP-74057) is an inhibitor of MEK activity and activation with favorable pharmacokinetic properties for sustained in vivo pathway inhibition.

1 reference

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12 July 2018

IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children's Oncology Group

1 reference

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12 July 2018

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

1 reference

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12 July 2018

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.

1 reference

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12 July 2018

Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas.

1 reference

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12 July 2018

Profiling critical cancer gene mutations in clinical tumor samples

1 reference

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12 July 2018

Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.

1 reference

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12 July 2018

Mutational profile of GNAQQ209 in human tumors.

1 reference

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12 July 2018

RAS signaling dysregulation in human embryonal Rhabdomyosarcoma.

1 reference

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12 July 2018

Recurring mutations found by sequencing an acute myeloid leukemia genome

1 reference

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12 July 2018

PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches

1 reference

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12 July 2018

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

1 reference

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12 July 2018

Activating mutations in ALK provide a therapeutic target in neuroblastoma.

1 reference

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12 July 2018

Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271129

12 July 2018

Addiction to elevated insulin-like growth factor I receptor and initial modulation of the AKT pathway define the responsiveness of rhabdomyosarcoma to the targeting antibody.

1 reference

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12 July 2018

An integrated genomic analysis of human glioblastoma multiforme

1 reference

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12 July 2018

Identification of ALK as a major familial neuroblastoma predisposition gene

1 reference

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12 July 2018

Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors.

1 reference

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12 July 2018

PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound.

1 reference

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12 July 2018

Cardio-facio-cutaneous and Noonan syndromes due to mutations in the RAS/MAPK signalling pathway: genotype-phenotype relationships and overlap with Costello syndrome.

1 reference

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12 July 2018

Rhabdomyosarcoma in a patient with Noonan syndrome phenotype and review of the literature.

1 reference

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12 July 2018

Hyperactive Ras in developmental disorders and cancer

1 reference

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12 July 2018

Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

1 reference

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12 July 2018

Mutations in PIK3CA are infrequent in neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271129

12 July 2018

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations.

1 reference

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12 July 2018

Mutations of the PTPN11 and RAS genes in rhabdomyosarcoma and pediatric hematological malignancies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271129

12 July 2018

BRAF mutation predicts sensitivity to MEK inhibition

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12 July 2018

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12 July 2018

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

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12 July 2018

Mutations of the BRAF gene in human cancer

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12 July 2018

N-ras gene activation in the RD human rhabdomyosarcoma cell line.

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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25 September 2018

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome.

1 reference

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Mutations in the BRAF and N-ras genes in childhood acute lymphoblastic leukaemia.

1 reference

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25 September 2018

High-throughput oncogene mutation profiling in human cancer

1 reference

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7 December 2018

describes a project that uses

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Identifiers

10.1158/1078-0432.CCR-11-2056

1 reference

Europe PubMed Central

9 August 2017

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Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

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