(Q35732874)

10 August 2017

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title

The ABCs of artificial antigen presentation (English)

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10 August 2017

Jiyun V Kim

1

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10 August 2017

Jean-Baptiste Latouche

series ordinal

2

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10 August 2017

Isabelle Rivière

series ordinal

3

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10 August 2017

Michel Sadelain

series ordinal

4

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10 August 2017

1 April 2004

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10 August 2017

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10 August 2017

22

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10 August 2017

4

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10 August 2017

403-410

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https://scigraph.springernature.com/pub.10.1038/nbt955

10 August 2017

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Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.

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A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes

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Large-scale production of CD4+ T cells from HIV-1-infected donors after CD3/CD28 costimulation

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Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.

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Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cell-based therapies and studies related to the expansion of double-positive T-cells during aging

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Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig–coated artificial antigen-presenting cells

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7 January 2021

HLA tetramer-based artificial antigen-presenting cells for stimulation of CD4+ T cells

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7 January 2021

Artificial antigen-presenting cells as a tool to exploit the immune 'synapse'.

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7 January 2021

Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

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Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

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7 January 2021

Exosomes: composition, biogenesis and function

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7 January 2021

Malignant effusions and immunogenic tumour-derived exosomes

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7 January 2021

Exosomes as potent cell-free peptide-based vaccine. II. Exosomes in CpG adjuvants efficiently prime naive Tc1 lymphocytes leading to tumor rejection

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7 January 2021

B lymphocytes secrete antigen-presenting vesicles

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7 January 2021

Exosomes as a tumor vaccine: enhancing potency through direct loading of antigenic peptides

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7 January 2021

Dendritic cells and the control of immunity

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7 January 2021

Spinning molecular immunology into successful immunotherapy

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7 January 2021

Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

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7 January 2021

In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens

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7 January 2021

T-cell therapy of cytomegalovirus and human immunodeficiency virus infection

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7 January 2021

Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood.

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7 January 2021

Antigen-dependent CD28 signaling selectively enhances survival and proliferation in genetically modified activated human primary T lymphocytes

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7 January 2021

Cancer patient T cells genetically targeted to prostate-specific membrane antigen specifically lyse prostate cancer cells and release cytokines in response to prostate-specific membrane antigen

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7 January 2021

Differential expression of human major histocompatibility class I loci: HLA-A, -B, and -C.

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7 January 2021

Binding of peptides with basic residues to membranes containing acidic phospholipids

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7 January 2021

PIP(2) and proteins: interactions, organization, and information flow

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7 January 2021

Electrostatics and reduction of dimensionality produce apparent cooperativity when basic peptides bind to acidic lipids in membranes

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7 January 2021

The synapse assembly model.

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7 January 2021

Correlation of a dynamic model for immunological synapse formation with effector functions: two pathways to synapse formation.

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7 January 2021

Direct stimulation of naïve T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules

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7 January 2021

T cell fitness determined by signal strength

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7 January 2021

Targeting tumours with genetically enhanced T lymphocytes

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7 January 2021

The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens

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7 January 2021

Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production

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7 January 2021

4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function

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7 January 2021

Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway

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7 January 2021

OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells

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7 January 2021

Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4+ T cells

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7 January 2021

Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

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7 January 2021

The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE.

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7 January 2021

Interaction Between ICOS-B7RP1 and B7-CD28 Costimulatory Pathways in Alloimmune Responses In Vivo

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7 January 2021

Costimulation of memory T-cells by ICOS: a potential therapeutic target for autoimmunity?

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7 January 2021

A role for inducible costimulator protein in the CD28- independent mechanism of resistance to Toxoplasma gondii.

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7 January 2021

T-cell co-stimulation through B7RP-1 and ICOS

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7 January 2021

Use of tumor-infiltrating lymphocytes and interleukin-2 in the immunotherapy of patients with metastatic melanoma. A preliminary report

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7 January 2021

IL-12 in conjunction with dendritic cells enhances antiviral CD8+ CTL responses in vitro

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7 January 2021

IL-12: a promising adjuvant for cancer vaccination

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7 January 2021

Cytokine control of memory T-cell development and survival

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7 January 2021

Interleukin-2 and interleukin-15: immunotherapy for cancer.

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7 January 2021

The contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for the immunotherapy of rheumatological diseases

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7 January 2021

IL-7 enhances peripheral T cell reconstitution after allogeneic hematopoietic stem cell transplantation

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7 January 2021

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

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7 January 2021

IL-7 Stimulates T Cell Renewal Without Increasing Viral Replication in Simian Immunodeficiency Virus-Infected Macaques

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7 January 2021

IL-21 up-regulates the expression of genes associated with innate immunity and Th1 response

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7 January 2021

Cutting edge: antigen-independent CD8 T cell proliferation.

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7 January 2021

Eradication of systemic B-cell tumors by genetically targeted human T lymphocytes co-stimulated by CD80 and interleukin-15.

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7 January 2021

Potential therapeutic role for cytokine or adhesion molecule manipulation in Crohn's disease: in the shadow of infliximab?

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7 January 2021

Interleukin 21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon gamma-producing Th1 cells

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7 January 2021

Tumor-derived exosomes: a new source of tumor rejection antigens

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7 January 2021

Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

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7 January 2021

Adoptive transfer of costimulated T cells induces lymphocytosis in patients with relapsed/refractory non-Hodgkin lymphoma following CD34+-selected hematopoietic cell transplantation

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7 January 2021

Molecular remission of CML after autotransplantation followed by adoptive transfer of costimulated autologous T cells

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7 January 2021

Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells

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7 January 2021

Prostate cancer: advances in immunotherapy

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7 January 2021

CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma.

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7 January 2021

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

1 reference

7 January 2021

Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accomp

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7 January 2021

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7 January 2021

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

1 reference

7 January 2021

The biology of IL-12: coordinating innate and adaptive immune responses

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7 January 2021

The immunological synapse.

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7 January 2021

Identifiers

DOI

10.1038/NBT955

1 reference

10 August 2017

1 reference