(Q35736694)

10 August 2017

title

Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin (English)

1 reference

Solute carrier family 6 member 18

10 August 2017

main subject

1 reference

amino acid transmembrane transporter activity

GOA release 2020-03-11

1 reference

Solute carrier family 6 (neurotransmitter transporter), member 18

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Stephen J Fairweather

object named as

Stephen J Fairweather

1

0 references

Dieter Schmoll

object named as

Dieter Schmoll

6

0 references

Megan L O'Mara

object named as

Megan L O'Mara

7

0 references

author name string

Angelika Bröer

2

1 reference

10 August 2017

Nandhitha Subramanian

3

1 reference

10 August 2017

Emrah Tumer

4

1 reference

10 August 2017

Qi Cheng

5

1 reference

10 August 2017

Stefan Bröer

8

1 reference

10 August 2017

language of work or name

English

0 references

publication date

3 August 2015

1 reference

Journal of Biological Chemistry

10 August 2017

published in

1 reference

10 August 2017

volume

290

1 reference

10 August 2017

issue

40

1 reference

10 August 2017

page(s)

24308-24325

1 reference

describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4591816/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Mice lacking neutral amino acid transporter B(0)AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control

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Human intestine luminal ACE2 and amino acid transporter expression increased by ACE-inhibitors.

12 July 2018

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The role of renin-angiotensin system modulation on treatment and prevention of liver diseases

12 July 2018

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Structure and regulatory interactions of the cytoplasmic terminal domains of serotonin transporter.

12 July 2018

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From gene to protein-experimental and clinical studies of ACE2 in blood pressure control and arterial hypertension

12 July 2018

1 reference

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An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter

12 July 2018

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Clinical perspectives and fundamental aspects of local cardiovascular and renal Renin-Angiotensin systems

12 July 2018

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Enterocyte-specific regulation of the apical nutrient transporter SLC6A19 (B(0)AT1) by transcriptional and epigenetic networks

12 July 2018

1 reference

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Loss of collectrin, an angiotensin-converting enzyme 2 homolog, uncouples endothelial nitric oxide synthase and causes hypertension and vascular dysfunction

12 July 2018

1 reference

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X-ray structure of dopamine transporter elucidates antidepressant mechanism

12 July 2018

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Diseases associated with general amino acid transporters of the solute carrier 6 family (SLC6).

12 July 2018

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Epithelial neutral amino acid transporters: lessons from mouse models

12 July 2018

1 reference

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ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation

12 July 2018

1 reference

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Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1.

12 July 2018

1 reference

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Tmem27 dimerization, deglycosylation, plasma membrane depletion, and the extracellular Phe-Phe motif are negative regulators of cleavage by Bace2.

12 July 2018

1 reference

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The solute carrier 6 family of transporters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Consideration of allosterism and interacting proteins in the physiological functions of the serotonin transporter

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Impaired nutrient signaling and body weight control in a Na+ neutral amino acid cotransporter (Slc6a19)-deficient mouse

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Synuclein modulation of monoamine transporters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters

12 July 2018

1 reference

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Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Regulation of dopamine transporter function by protein-protein interactions: new discoveries and methodological challenges.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Molecular mechanism of secretory vesicle docking

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

The rocking bundle: a mechanism for ion-coupled solute flux by symmetrical transporters.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Glucose enhances collectrin protein expression in insulin-producing MIN6 beta cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Orphan transporter SLC6A18 is renal neutral amino acid transporter B0AT3

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Collectrin is involved in the development of salt-sensitive hypertension by facilitating the membrane trafficking of apical membrane proteins via interaction with soluble N-ethylmaleiamide-sensitive factor attachment protein receptor complex.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Dopamine transporter/syntaxin 1A interactions regulate transporter channel activity and dopaminergic synaptic transmission

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

PROMALS3D: a tool for multiple protein sequence and structure alignments

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Core proteins of the secretory machinery

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Role of SNAREs and H+-ATPase in the targeting of proton pump-coated vesicles to collecting duct cell apical membrane.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Essential role for collectrin in renal amino acid transport

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Oligomerization of neurotransmitter transporters: a ticket from the endoplasmic reticulum to the plasma membrane

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

The role of SNARE proteins in trafficking and function of neurotransmitter transporters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Principles of selective ion transport in channels and pumps

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

The N-terminus of the norepinephrine transporter regulates the magnitude and selectivity of the transporter-associated leak current

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

SNARE complexes prepare for membrane fusion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Sodium-dependent neurotransmitter transporters: oligomerization as a determinant of transporter function and trafficking

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Refinement of homology-based protein structures by molecular dynamics simulation techniques

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Syntaxin 1A Inhibits GABA Flux, Efflux, and Exchange Mediated by the Rat Brain GABA Transporter GAT1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

HADDOCK: a protein-protein docking approach based on biochemical or biophysical information

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

The interaction between syntaxin 1A and cystic fibrosis transmembrane conductance regulator Cl- channels is mechanistically distinct from syntaxin 1A-SNARE interactions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

SNARE expression and localization in renal epithelial cells suggest mechanism for variability of trafficking phenotypes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Substrates regulate gamma-aminobutyric acid transporters in a syntaxin 1A-dependent manner

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Regulation of glycine transporters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Interaction of syntaxins with epithelial ion channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Human syntaxin 3 is localized apically in human intestinal cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

VMD: visual molecular dynamics

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Definition and testing of the GROMOS force-field versions 54A7 and 54B7

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

The alternating-access mechanism of MFS transporters arises from inverted-topology repeats.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Renal imino acid and glycine transport system ontogeny and involvement in developmental iminoglycinuria.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Tissue-specific amino acid transporter partners ACE2 and collectrin differentially interact with hartnup mutations.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

A protein complex in the brush-border membrane explains a Hartnup disorder allele.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Tmem27: a cleaved and shed plasma membrane protein that stimulates pancreatic beta cell proliferation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Steady-state kinetic characterization of the mouse B(0)AT1 sodium-dependent neutral amino acid transporter.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Characterization of mouse amino acid transporter B0AT1 (slc6a19).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Intracellular domains of a rat brain GABA transporter that govern transport.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

25 September 2018

Xenopus laevis Oocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Syntaxin 1A up-regulates GABA transporter expression by subcellular redistribution.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4591816

Regulation of glycine transporters

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.648519

SNAP-25/Syntaxin 1A Complex Functionally Modulates Neurotransmitter γ-Aminobutyric Acid Reuptake

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.648519

Molecular dynamics with coupling to an external bath

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M115.648519

The HNF-1alpha-SNARE connection

21 January 2018

1 reference

12 December 2020

Collectrin, an X-linked, angiotensin converting enzyme 2 homolog, causes hypertension in a rat strain through gene-gene and gene-environment interactions: relevance to human hypertension

1 reference

12 December 2020

A comprehensive structure-based alignment of prokaryotic and eukaryotic neurotransmitter/Na+ symporters (NSS) aids in the use of the LeuT structure to probe NSS structure and function

1 reference

12 December 2020

[Collectrin: a new component of the renin-angiotensin system?]

1 reference

12 December 2020

Aminoaciduria and altered renal expression of luminal amino acid transporters in mice lacking novel gene collectrin

1 reference

12 December 2020

On the Validation of Molecular Dynamics Simulations of Saturated and cis-Monounsaturated Phosphatidylcholine Lipid Bilayers: A Comparison with Experiment

1 reference

12 December 2020

SNARE-ing neurotransmitter transporters

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M115.648519

1 reference

10 August 2017

1 reference

10 August 2017

1 reference