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Mechanisms involved in regulating DNA replication origins during the cell cycle and in response to DNA damage.
scientific article published on January 2004
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Mechanisms involved in regulating DNA replication origins during the cell cycle and in response to DNA damage
(English)
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
main subject
DNA damage
0 references
author
John Francis Xavier Diffley
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
Lucy Drury
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
author name string
Anne Early
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
language of work or name
English
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publication date
1 January 2004
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stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
number of pages
8
1 reference
based on heuristic
inferred from page(s)
published in
Philosophical Transactions of the Royal Society B
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
volume
359
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
issue
1441
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
page(s)
31-38
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
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Deregulated G1-cyclin expression induces genomic instability by preventing efficient pre-RC formation
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MCM2-7 proteins are essential components of prereplicative complexes that accumulate cooperatively in the nucleus during G1-phase and are required to establish, but not maintain, the S-phase checkpoint
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The DNA replication checkpoint response stabilizes stalled replication forks
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Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
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Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms
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Initiating DNA synthesis: from recruiting to activating the MCM complex
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XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis
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27 July 2018
Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase
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Clb/Cdc28 kinases promote nuclear export of the replication initiator proteins Mcm2-7.
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Sensing and responding to DNA damage.
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27 July 2018
G1-phase and B-type cyclins exclude the DNA-replication factor Mcm4 from the nucleus
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27 July 2018
Phosphorylation controls timing of Cdc6p destruction: A biochemical analysis
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27 July 2018
Activation of dormant origins of DNA replication in budding yeast
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27 July 2018
Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication
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27 July 2018
Esa1p is an essential histone acetyltransferase required for cell cycle progression
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27 July 2018
Inhibitory phosphorylation of the APC regulator Hct1 is controlled by the kinase Cdc28 and the phosphatase Cdc14.
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27 July 2018
AAA+: A class of chaperone-like ATPases associated with the assembly, operation, and disassembly of protein complexes
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27 July 2018
Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex
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27 July 2018
A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication
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27 July 2018
Evidence for a Cdc6p-independent mitotic resetting event involving DNA polymerase alpha.
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27 July 2018
Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin
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27 July 2018
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27 July 2018
Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants
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27 July 2018
The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast
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27 July 2018
Yeast Hct1 is a regulator of Clb2 cyclin proteolysis
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27 July 2018
SIC1 is ubiquitinated in vitro by a pathway that requires CDC4, CDC34, and cyclin/CDK activities
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27 July 2018
Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex
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27 July 2018
A novel Mcm1-dependent element in the SWI4, CLN3, CDC6, and CDC47 promoters activates M/G1-specific transcription
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27 July 2018
Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast
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27 July 2018
The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.
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27 July 2018
Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast
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27 July 2018
Morphogenesis in the yeast cell cycle: regulation by Cdc28 and cyclins
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27 July 2018
CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae
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27 July 2018
A new pair of B-type cyclins from Saccharomyces cerevisiae that function early in the cell cycle
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27 July 2018
Cell cycle-dependent phosphorylation and dephosphorylation of the yeast DNA polymerase alpha-primase B subunit
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27 July 2018
Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.
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27 July 2018
DAF1, a mutant gene affecting size control, pheromone arrest, and cell cycle kinetics of Saccharomyces cerevisiae
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27 July 2018
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27 July 2018
A family of cyclin homologs that control the G1 phase in yeast
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27 July 2018
The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.
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27 July 2018
CLB5: a novel B cyclin from budding yeast with a role in S phase
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27 July 2018
DNA synthesis control in yeast: an evolutionarily conserved mechanism for regulating DNA synthesis genes?
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27 July 2018
A central role for DNA replication forks in checkpoint activation and response
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25 September 2018
Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair.
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25 September 2018
Separate SCF(CDC4) recognition elements target Cdc6 for proteolysis in S phase and mitosis.
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25 September 2018
Uninterrupted MCM2-7 function required for DNA replication fork progression
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25 September 2018
The Cdt1 protein is required to license DNA for replication in fission yeast
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25 September 2018
The cyclin-dependent kinase Cdc28p regulates distinct modes of Cdc6p proteolysis during the budding yeast cell cycle.
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25 September 2018
NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p
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25 September 2018
Nucleotide-dependent prereplicative complex assembly by Cdc6p, a homolog of eukaryotic and prokaryotic clamp-loaders.
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25 September 2018
CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.
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25 September 2018
S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state.
1 reference
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25 September 2018
The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication
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25 September 2018
Heat-inducible degron: a method for constructing temperature-sensitive mutants.
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25 September 2018
Two steps in the assembly of complexes at yeast replication origins in vivo
1 reference
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PubMed Central
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25 September 2018
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in response to DNA damage.
1 reference
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25 September 2018
Regulation of DNA-replication origins during cell-cycle progression
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15065654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
CDK Inactivation Is the Only Essential Function of the APC/C and the Mitotic Exit Network Proteins for Origin Resetting during Mitosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15065654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The stability of the Cdc6 protein is regulated by cyclin-dependent kinase/cyclin B complexes in Saccharomyces cerevisiae
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/15065654
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1098/RSTB.2003.1362
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
PMCID
1693309
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
PubMed ID
15065654
1 reference
stated in
Europe PubMed Central
PMCID
1693309
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15065654%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 December 2019
ResearchGate publication ID
8635249
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