(Q35739055)

10 August 2017

title

Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity (English)

1 reference

Katherine L. Seley-Radtke

10 August 2017

1 reference

Dirk Jochmans

2

0 references

Katherine L Seley-Radtke

7

0 references

Eric J Snijder

Eric J Snijder

5

0 references

Johan Neyts

Johan Neyts

6

0 references

Clara C Posthuma

4

Clara C Posthuma

1 reference

10 August 2017

Hannah L Peters

1

1 reference

10 August 2017

Adriaan H de Wilde

3

1 reference

10 August 2017

language of work or name

English

0 references

publication date

23 May 2015

1 reference

10 August 2017

number of pages

4

1 reference

Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

1 reference

10 August 2017

volume

25

1 reference

10 August 2017

issue

15

1 reference

10 August 2017

page(s)

2923-2926

1 reference

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Synthetic Routes to a Series of Proximal and Distal 2'-Deoxy Fleximers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaques

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Coronaviruses lacking exoribonuclease activity are susceptible to lethal mutagenesis: evidence for proofreading and potential therapeutics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Identification of new human coronaviruses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Identification of catalytic amino acids in the human GTP fucose pyrophosphorylase active site

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Substrate discrimination by the human GTP fucose pyrophosphorylase.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Ribavirin and interferon-beta synergistically inhibit SARS-associated coronavirus replication in animal and human cell lines.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Inhibition of SARS coronavirus infection in vitro with clinically approved antiviral drugs

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Coronavirus as a possible cause of severe acute respiratory syndrome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational study

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Therapeutic options for Middle East respiratory syndrome coronavirus (MERS-CoV)--possible lessons from a systematic review of SARS-CoV therapy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Design, synthesis and evaluation of a novel double pro-drug: INX-08189. A new clinical candidate for hepatitis C virus.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Unexpected inhibition of S-adenosyl-L-homocysteine hydrolase by a guanosine nucleoside

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

"Fleximers". Design and synthesis of a new class of novel shape-modified nucleosides(1).

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Acyclovir inhibition of viral DNA chain elongation in herpes simplex virus-infected cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Acyclovir triphosphate is a suicide inactivator of the herpes simplex virus DNA polymerase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466200

Significant enhancement of the Stille reaction with a new combination of reagents-copper(I) iodide with cesium fluoride

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26048809

12 December 2020

inferred from PubMed ID database lookup

"Molecular chameleons". Design and synthesis of C-4-substituted imidazole fleximers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26048809

12 December 2020

inferred from PubMed ID database lookup

"Fleximers". Design and synthesis of two novel split nucleosides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26048809

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.BMCL.2015.05.039

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference