(Q35740663)

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Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer.

scientific article published on 6 August 2015

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scholarly article

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Europe PubMed Central

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21 February 2020

Signal Transducer and Activator of Transcription 3, Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer (English)

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21 February 2020

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Nagaraj Nagathihalli

1

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21 February 2020

Harold L. Moses

10

object named as

Harold L Moses

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21 February 2020

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Jason A Castellanos

2

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21 February 2020

Chanjuan Shi

3

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21 February 2020

Yugandhar Beesetty

4

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21 February 2020

Michelle L Reyzer

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21 February 2020

Richard Caprioli

6

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21 February 2020

Xi Chen

7

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21 February 2020

Alex J Walsh

8

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21 February 2020

Melissa C Skala

9

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21 February 2020

Nipun B Merchant

11

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21 February 2020

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publication date

7 August 2015

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21 February 2020

Gastroenterology

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21 February 2020

149

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21 February 2020

7

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21 February 2020

1932-1943.e9

1 reference

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21 February 2020

Compression of pancreatic tumor blood vessels by hyaluronan is caused by solid stress and not interstitial fluid pressure

1 reference

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12 July 2018

Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival

1 reference

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12 July 2018

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

1 reference

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12 July 2018

Transport properties of pancreatic cancer describe gemcitabine delivery and response

1 reference

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12 July 2018

Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer

1 reference

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12 July 2018

nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer

1 reference

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12 July 2018

Mouse models of pancreatic cancer

1 reference

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12 July 2018

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

1 reference

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12 July 2018

Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness.

1 reference

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12 July 2018

Magnetization transfer MRI in pancreatic cancer xenograft models.

1 reference

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12 July 2018

Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma

1 reference

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12 July 2018

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

1 reference

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12 July 2018

Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth

1 reference

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12 July 2018

Role of pancreatic stellate cells in pancreatic cancer metastasis.

1 reference

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12 July 2018

CD10+ pancreatic stellate cells enhance the progression of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863449

12 July 2018

Targeted inhibition of SRC kinase signaling attenuates pancreatic tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863449

12 July 2018

Modulating tumor vasculature through signaling inhibition to improve cytotoxic therapy

1 reference

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12 July 2018

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

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12 July 2018

Epithelial-mesenchymal transition markers in pancreatic ductal adenocarcinoma

1 reference

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12 July 2018

Cancer statistics, 2008

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12 July 2018

Mechanisms of disease: chronic inflammation and cancer in the pancreas--a potential role for pancreatic stellate cells?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863449

12 July 2018

Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863449

12 July 2018

MALDI-MS-based imaging of small molecules and proteins in tissues

1 reference

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12 July 2018

Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression

1 reference

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12 July 2018

Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

1 reference

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12 July 2018

STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3.

1 reference

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12 July 2018

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

1 reference

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12 July 2018

Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics

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12 July 2018

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

1 reference

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12 July 2018

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

1 reference

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12 July 2018

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

1 reference

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12 July 2018

Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863449

12 July 2018

Pancreatic cancer-associated stellate cells: A viable target for reducing immunosuppression in the tumor microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863449

25 September 2018

Erlotinib prolongs survival in pancreatic cancer by blocking gemcitabine-induced MAPK signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863449

25 September 2018

Scoring of collagen organization in healthy and diseased human dermis by multiphoton microscopy.

1 reference

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25 September 2018

Decreased blood flow with increased metabolic activity: a novel sign of pancreatic tumor aggressiveness

1 reference

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25 September 2018

Conditional inactivation of the TGF-beta type II receptor using Cre:Lox

1 reference

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25 September 2018

Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

1 reference

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12 December 2020

based on heuristic

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Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/26255562

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1053/J.GASTRO.2015.07.058

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255562%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26255562%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

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21 February 2020

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