(Q35749522)

10 August 2017

title

Evidence for proton transfer in the rate-limiting step of a fast-cleaving Varkud satellite ribozyme (English)

1 reference

10 August 2017

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M Duane Smith

1

1 reference

10 August 2017

Richard A Collins

series ordinal

2

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10 August 2017

language of work or name

English

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publication date

26 March 2007

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

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10 August 2017

volume

104

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10 August 2017

issue

14

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10 August 2017

page(s)

5818-5823

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describes a project that uses

10 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1851575/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Tertiary contacts distant from the active site prime a ribozyme for catalysis

27 July 2018

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Chemical rescue, multiple ionizable groups, and general acid-base catalysis in the HDV genomic ribozyme

27 July 2018

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Nucleobase catalysis in the hairpin ribozyme

27 July 2018

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The catalytic diversity of RNAs

27 July 2018

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Linkage between proton binding and folding in RNA: implications for RNA catalysis

27 July 2018

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Role of an active site adenine in hairpin ribozyme catalysis

27 July 2018

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Ribozyme catalysis: not different, just worse

27 July 2018

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Efficient, pH-dependent RNA ligation by the VS ribozyme in trans

27 July 2018

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Ionization of a Critical Adenosine Residue in theNeurosporaVarkud Satellite Ribozyme Active Site†

27 July 2018

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Mechanistic considerations for general acid-base catalysis by RNA: revisiting the mechanism of the hairpin ribozyme

27 July 2018

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Functional involvement of G8 in the hairpin ribozyme cleavage mechanism

27 July 2018

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Rapid formation of a solvent-inaccessible core in the Neurospora Varkud satellite ribozyme

27 July 2018

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Intramolecular secondary structure rearrangement by the kissing interaction of the Neurospora VS ribozyme

27 July 2018

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General acid-base catalysis in the mechanism of a hepatitis delta virus ribozyme

27 July 2018

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A secondary-structure model for the self-cleaving region of Neurospora VS RNA.

27 July 2018

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27 July 2018

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27 July 2018

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The Intrinsic PkA-Values of Functional Groups in Enzymes: Improper Deductions from the Ph-Dependence of Steady-State Parameter

27 July 2018

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RNAs with dual specificity and dual RNAs with similar specificity

27 July 2018

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Catalytic strategies of the hepatitis delta virus ribozymes

21 January 2018

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Nucleobase participation in ribozyme catalysis

21 January 2018

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Exceptionally fast self-cleavage by a Neurospora Varkud satellite ribozyme

21 January 2018

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Catalytic roles for proton transfer and protonation in ribozymes

21 January 2018

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pH dependencies of the Tetrahymena ribozyme reveal an unconventional origin of an apparent pKa.

21 January 2018

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Comparison of pH dependencies of the Tetrahymena ribozyme reactions with RNA 2'-substituted and phosphorothioate substrates reveals a rate-limiting conformational step

21 January 2018

1 reference

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Role of an active site guanine in hairpin ribozyme catalysis probed by exogenous nucleobase rescue

21 January 2018

1 reference

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pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Direct pK(a) measurement of the active-site cytosine in a genomic hepatitis delta virus ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Solvent isotope effects on alpha-glucosidase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Functional group requirements in the probable active site of the VS ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

4-thio-U cross-linking identifies the active site of the VS ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

The A730 loop is an important component of the active site of the VS ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Imidazole rescue of a cytosine mutation in a self-cleaving ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Triosephosphate isomerase catalysis is diffusion controlled. Appendix: Analysis of triose phosphate equilibria in aqueous solution by 31P NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Significant kinetic solvent isotope effects in folding of the catalytic RNA from the hepatitis delta virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Hammerheads derived from sTRSV show enhanced cleavage and ligation rate constants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

A long-range pseudoknot is required for activity of the Neurospora VS ribozyme

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1851575

Fast Cleavage Kinetics of a Natural Hammerhead Ribozyme

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0608864104

Identification of the catalytic subdomain of the VS ribozyme and evidence for remarkable sequence tolerance in the active site loop

21 January 2018

1 reference

12 December 2020

Rearrangement of substrate secondary structure facilitates binding to the Neurospora VS ribozyme

1 reference

12 December 2020

Solvent and solvent proton dependent steps in the galactose oxidase reaction

1 reference

12 December 2020

Reaction conditions and kinetics of self-cleavage of a ribozyme derived from Neurospora VS RNA

1 reference

12 December 2020

Hammerhead ribozymes with a faster cleavage rate

1 reference

12 December 2020

Catalytic mechanism of Escherichia coli glycinamide ribonucleotide transformylase probed by site-directed mutagenesis and pH-dependent studies

1 reference

12 December 2020

The first crystal structure of an RNA racemate

1 reference

12 December 2020

Catalytic core structure of the trans-acting HDV ribozyme is subtly influenced by sequence variation outside the core

1 reference

12 December 2020

Rearrangement of a stable RNA secondary structure during VS ribozyme catalysis

1 reference

12 December 2020

Involvement of a cytosine side chain in proton transfer in the rate-determining step of ribozyme self-cleavage

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0608864104

1 reference

10 August 2017

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1 reference

10 August 2017

1 reference