(Q35750137)

10 August 2017

1 reference

title

The role of translation in neoplastic transformation from a pathologist's point of view (English)

1 reference

10 August 2017

Igor B Rosenwald

1

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PubMed ID

15094773

10 August 2017

language of work or name

English

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publication date

1 April 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

3230-3247

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10 August 2017

18

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207552

10 August 2017

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cites work

Translational regulation of ribonucleotide reductase by eukaryotic initiation factor 4E links protein synthesis to the control of DNA replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

The retinoblastoma protein pathway and the restriction point

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Mammalian unfolded protein response inhibits cyclin D1 translation and cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

PS6K amplification characterizes a small subset of anaplastic meningiomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Overexpression of eukaryotic protein synthesis initiation factor 4E in HeLa cells results in aberrant growth and morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Regulation of LEF-1/TCF transcription factors by Wnt and other signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Cloning and characterization of human eIF4E genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Translational control and metastatic progression: enhanced activity of the mRNA cap-binding protein eIF-4E selectively enhances translation of metastasis-related mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Rapamycin inhibition of the G1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

The interdependence of nuclear structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Differential modulation of cyclin gene expression by MYC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Genetics of myeloid leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

NF-kappa B-like factors mediate interleukin 1 induction of c-myc gene transcription in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

APC mutations are sufficient for the growth of early colorectal adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Transcription by RNA polymerases I and III: a potential link between cell growth, protein synthesis and the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

How cells read TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Biochemical analysis of the eIF2beta gamma complex reveals a structural function for eIF2alpha in catalyzed nucleotide exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Translational control of the antiapoptotic function of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

The target of rapamycin (TOR) proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Eukaryotic translation initiation factor 4E regulates expression of cyclin D1 at transcriptional and post-transcriptional levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Does the ribosome translate cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

The transcriptional program of a human B cell line in response to Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Cyclin-dependent kinases govern formation and maintenance of the nucleolus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Transformed cells have lost control of ribosome number through their growth cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Not just for housekeeping: protein initiation and elongation factors in cell growth and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Reduced expression of transforming growth factor beta type I receptor contributes to the malignancy of human colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

What is the restriction point?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Cyclin D Expression Is Controlled Post-transcriptionally via a Phosphatidylinositol 3-Kinase/Akt-dependent Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

Progressive amplification and overexpression of the eukaryotic initiation factor 4E gene in different zones of head and neck cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

p53 represses ribosomal gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Eukaryotic initiation factor-4E in superficial and muscle invasive bladder cancer and its correlation with vascular endothelial growth factor expression and tumour progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Antisense RNA to eIF4E suppresses oncogenic properties of a head and neck squamous cell carcinoma cell line.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

BCR-ABL independence and LYN kinase overexpression in chronic myelogenous leukemia cells selected for resistance to STI571.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

The mitogen-activated protein (MAP) kinase ERK induces tRNA synthesis by phosphorylating TFIIIB.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Identification of c-MYC as a target of the APC pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

p53 activation results in rapid dephosphorylation of the eIF4E-binding protein 4E-BP1, inhibition of ribosomal protein S6 kinase and inhibition of translation initiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Coupled transcription and translation within nuclei of mammalian cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Regulation of c-myc expression by Ras/Raf signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Neoplastic progression in melanoma and colon cancer is associated with increased expression and activity of the interferon-inducible protein kinase, PKR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Lessons from hereditary colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Overexpression of eukaryotic initiation factor 4E (eIF4E) in breast carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Survival of patients with chronic-phase chronic myeloid leukaemia on imatinib after failure on interferon alfa

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Detection of the proto-oncogene eIF4E in surgical margins may predict recurrence in head and neck cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

MYC oncogenes and human neoplastic disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Activators and target genes of Rel/NF-kappaB transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

More than one way to skin a catenin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Dual function of the messenger RNA cap structure in poly(A)-tail-promoted translation in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Upregulated expression of the genes encoding translation initiation factors eIF-4E and eIF-2alpha in transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Deregulation of protein synthesis as a mechanism of neoplastic transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Upregulation of protein synthesis initiation factor eIF-4E is an early event during colon carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Expression of eukaryotic translation initiation factors 4E and 2alpha is increased frequently in bronchioloalveolar but not in squamous cell carcinomas of the lung

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Expression of translation initiation factor eIF-2alpha is increased in benign and malignant melanocytic and colonic epithelial neoplasms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Early signals in the mitogenic response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Cell cycle deregulation in B-cell lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

The role of c-myc in cellular growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

1 reference

7 January 2021

The emerging roles of translation factor eIF4E in the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Inhibition of Myc-dependent apoptosis by eukaryotic translation initiation factor 4E requires cyclin D1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Elongation factor-1 alpha gene determines susceptibility to transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Expression of eukaryotic translation initiation factors 4E and 2alpha correlates with the progression of thyroid carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Cloning and characterization of full-length human ribosomal protein L15 cDNA which was overexpressed in esophageal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Repression of RNA polymerase III transcription by the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Coordination between cell growth and cell cycle transit in animal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207552

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207552

1 reference

10 August 2017

1 reference

PubMed ID

15094773