(Q35753517)

10 August 2017

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title

Development of herpesvirus-based episomally maintained gene delivery vectors (English)

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10 August 2017

Adrian Whitehouse

3

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Robert E White

object named as

Robert E White

series ordinal

2

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author name string

Michael A Calderwood

series ordinal

1

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10 August 2017

language of work or name

English

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publication date

1 April 2004

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Expert Opinion on Biological Therapy

10 August 2017

published in

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10 August 2017

volume

4

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10 August 2017

issue

4

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10 August 2017

page(s)

493-505

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Non-viral and hybrid vectors in human gene therapy: an update

10 August 2017

cites work

1 reference

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Gene therapy. Second child in French trial is found to have leukemia

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A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

21 January 2018

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A phage integrase directs efficient site-specific integration in human cells

21 January 2018

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Mammalian genomes contain active recombinase recognition sites

21 January 2018

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Site-specific genomic integration in mammalian cells mediated by phage phiC31 integrase

21 January 2018

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Stable correction of a genetic deficiency in human cells by an episome carrying a 115 kb genomic transgene

21 January 2018

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An element in intron 1 of the CFTR gene augments intestinal expression in vivo

21 January 2018

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Locus control regions: coming of age at a decade plus

21 January 2018

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Development and application of herpes simplex virus vectors for human gene therapy

21 January 2018

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Cancer gene therapy: fringe or cutting edge?

21 January 2018

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Genetically engineered HSV in the treatment of glioma: a review

21 January 2018

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Oncolytic viruses: clinical applications as vectors for the treatment of malignant gliomas

21 January 2018

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Engineering herpes simplex virus vectors for gene transfer to neurons

21 January 2018

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Herpes simplex virus type 1 promoter activity during latency establishment, maintenance, and reactivation in primary dorsal root neurons in vitro.

21 January 2018

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Herpes simplex virus type 1-based amplicon vector systems

21 January 2018

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The herpes simplex virus amplicon: A new eucaryotic defective-virus cloning-amplifying vector

21 January 2018

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HSV-1 amplicon vectors--simplicity and versatility

21 January 2018

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Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells

21 January 2018

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Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance region

21 January 2018

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A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells

21 January 2018

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The replicator of the Epstein-Barr virus latent cycle origin of DNA replication, oriP, is composed of multiple functional elements

21 January 2018

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The Epstein-Barr virus origin of plasmid replication, oriP, contains both the initiation and termination sites of DNA replication

21 January 2018

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Mapping genetic elements of Epstein-Barr virus that facilitate extrachromosomal persistence of Epstein-Barr virus-derived plasmids in human cells

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

The plasmid replicon of EBV consists of multiple cis-acting elements that facilitate DNA synthesis by the cell and a viral maintenance element

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Epstein-Barr virus nuclear antigen-1 is highly colocalized with interphase chromatin and its newly replicated regions in particular

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Epstein-Barr virus (EBV) nuclear antigen 1 colocalizes with cellular replication foci in the absence of EBV plasmids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Metaphase chromosome tethering is necessary for the DNA synthesis and maintenance of oriP plasmids but is insufficient for transcription activation by Epstein-Barr nuclear antigen 1.

21 January 2018

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Therapeutic gene delivery in human B-lymphoblastoid cells by engineered non-transforming infectious Epstein-Barr virus

21 January 2018

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21 January 2018

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DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

21 January 2018

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Genetic relationships between bovine herpesvirus 4 and the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri

21 January 2018

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Stable growth transformation of human T lymphocytes by herpesvirus saimiri

21 January 2018

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CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes

21 January 2018

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Identification of the novel K15 gene at the rightmost end of the Kaposi's sarcoma-associated herpesvirus genome

21 January 2018

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The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotype

21 January 2018

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The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cells

21 January 2018

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Identification of Lck-binding elements in tip of herpesvirus saimiri

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

A region of the Herpesvirus saimiri genome required for oncogenicity

21 January 2018

1 reference

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Herpesvirus saimiri-based gene delivery vectors maintain heterologous expression throughout mouse embryonic stem cell differentiation in vitro.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

In vivo episomal maintenance of a herpesvirus saimiri-based gene delivery vector

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Gene silencing as a threat to the success of gene therapy

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Development and optimization of herpes simplex virus vectors for multiple long-term gene delivery to the peripheral nervous system

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Expression from the herpes simplex virus type 1 latency-associated promoter in the murine central nervous system

21 January 2018

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https://api.crossref.org/works/10.1517%2F14712598.4.4.493

The herpesvirus saimiri ORF 73 regulatory region provides long-term transgene expression in human carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen 1 mediates episome persistence through cis-acting terminal repeat (TR) sequence and specifically binds TR DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

The latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus interacts preferentially with the terminal repeats of the genome in vivo and this complex is sufficient for episomal DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

The herpesvirus saimiri ORF73 gene product interacts with host-cell mitotic chromosomes and self-associates via its C terminus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

The terminal repeats and latency-associated nuclear antigen of herpesvirus saimiri are essential for episomal persistence of the viral genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

ORF73 of Herpesvirus Saimiri Strain C488 Tethers the Viral Genome to Metaphase Chromosomes and Binds to cis -Acting DNA Sequences in the Terminal Repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Generation and precise modification of a herpesvirus saimiri bacterial artificial chromosome demonstrates that the terminal repeats are required for both virus production and episomal persistence

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Herpesvirus genetics has come of age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Cloning and mutagenesis of the murine gammaherpesvirus 68 genome as an infectious bacterial artificial chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Virus reconstituted from infectious bacterial artificial chromosome (BAC)-cloned murine gammaherpesvirus 68 acquires wild-type properties in vivo only after excision of BAC vector sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

A new method for generating point mutations in bacterial artificial chromosomes by homologous recombination in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Allele replacement: an application that permits rapid manipulation of herpes simplex virus type 1 genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Cloning and mutagenesis of a herpesvirus genome as an infectious bacterial artificial chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Propagation and recovery of intact, infectious Epstein-Barr virus from prokaryotic to human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Spontaneous activation of the lytic cycle in cells infected with a recombinant Kaposi's sarcoma-associated virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Gene therapy progress and prospects: cystic fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

US gene therapy in crisis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

Epstein-Barr-based episomal chromosomes shuttle 100 kb of self-replicating circular human DNA in mouse cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.4.4.493

21 January 2018

Identifiers

DOI

10.1517/14712598.4.4.493

1 reference

10 August 2017

1 reference