(Q35754683)

10 August 2017

title

Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease (English)

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10 August 2017

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ChEBI release 2020-05-28

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9

S Przedborski

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10 August 2017

Vernice Jackson-Lewis

2

object named as

V Jackson-Lewis

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10 August 2017

L Lim

1

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10 August 2017

L C Wong

3

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10 August 2017

G H Shui

4

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10 August 2017

A X H Goh

5

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10 August 2017

S Kesavapany

6

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10 August 2017

A M Jenner

7

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10 August 2017

M Fivaz

8

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10 August 2017

M R Wenk

10

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10 August 2017

publication date

5 August 2011

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Cell Death & Differentiation

10 August 2017

published in

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10 August 2017

volume

19

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10 August 2017

issue

3

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10 August 2017

page(s)

416-427

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describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3278725/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/cdd.2011.105

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cites work

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Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.

2 October 2017

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The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations

2 October 2017

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Regulation of the autophagy protein LC3 by phosphorylation

2 October 2017

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p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

2 October 2017

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Subcellular organelle lipidomics in TLR-4-activated macrophages

2 October 2017

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PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

2 October 2017

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DJ-1, PINK1, and their effects on mitochondrial pathways

2 October 2017

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

2 October 2017

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Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity

2 October 2017

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Parkinson's disease: from monogenic forms to genetic susceptibility factors

2 October 2017

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

2 October 2017

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Culturing hippocampal neurons

2 October 2017

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Lower low-density lipoprotein cholesterol levels are associated with Parkinson's disease

2 October 2017

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Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled.

2 October 2017

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Elevated levels of oxidized cholesterol metabolites in Lewy body disease brains accelerate alpha-synuclein fibrilization

2 October 2017

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Effects of metabolic modifiers such as carnitines, coenzyme Q10, and PUFAs against different forms of neurotoxic insults: metabolic inhibitors, MPTP, and methamphetamine

2 October 2017

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Environmental toxins and alpha-synuclein in Parkinson's disease

2 October 2017

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Cholesterol homeostasis in neurons and glial cells

2 October 2017

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

2 October 2017

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Parkinson's disease: mechanisms and models

2 October 2017

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Some properties of the microsomal 2,3-oxidosqualene sterol cyclase

2 October 2017

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Energy-dependent uptake of N-methyl-4-phenylpyridinium, the neurotoxic metabolite of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine, by mitochondria.

2 October 2017

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Identified postnatal mesolimbic dopamine neurons in culture: morphology and electrophysiology.

12 July 2018

1 reference

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Alterations of cholesterol precursor levels in Alzheimer's disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Novel microfluidic platform for culturing neurons: culturing and biochemical analysis of neuronal components.

25 September 2018

1 reference

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Glycogen synthase kinase-3 beta and tau genes interact in Parkinson's and Alzheimer's diseases.

25 September 2018

1 reference

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Low LDL cholesterol and increased risk of Parkinson's disease: prospective results from Honolulu-Asia Aging Study

25 September 2018

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Alpha-synuclein adopts an alpha-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Uncoupling protein-2 is critical for nigral dopamine cell survival in a mouse model of Parkinson's disease.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Coenzyme Q induces nigral mitochondrial uncoupling and prevents dopamine cell loss in a primate model of Parkinson's disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Expression of cyclin-dependent kinase 5 and its activator p35 in models of induced apoptotic death in neurons of the substantia nigra in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation

25 September 2018

2 references

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2011.105

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278725

Serum Cholesterol Levels and the Risk of Parkinson's Disease

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDD.2011.105

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

21 January 2018

1 reference

12 December 2020

Glutamate-induced neuron death requires mitochondrial calcium uptake

1 reference

12 December 2020

Functional polymorphisms of the Lss and Fdft1 genes in laboratory rats

1 reference

12 December 2020

Statins and the risk of Parkinson disease: an update on the controversy

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDD.2011.105

1 reference

10 August 2017

1 reference

10 August 2017

1 reference