(Q35771493)

10 August 2017

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title

QT prolongation with antimicrobial agents: understanding the significance (English)

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10 August 2017

Robert C Owens

1

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10 August 2017

1 January 2004

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10 August 2017

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10 August 2017

64

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10 August 2017

10

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10 August 2017

1091-1124

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https://scigraph.springernature.com/pub.10.2165/00003495-200464100-00005

10 August 2017

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cites work

Efficacy and safety of d,l-sotalol in patients with ventricular tachycardia and in survivors of cardiac arrest

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12 December 2020

Torsades de pointes associated with antimicrobial therapy for pneumonia

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12 December 2020

Multiple mechanisms in the long-QT syndrome. Current knowledge, gaps, and future directions. The SADS Foundation Task Force on LQTS.

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12 December 2020

Drugs, QT interval abnormalities and ventricular arrhythmias.

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12 December 2020

Overview of electrocardiographic and cardiovascular safety data for sparfloxacin. Sparfloxacin Safety Group

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12 December 2020

Safety of non-antiarrhythmic drugs that prolong the QT interval or induce torsade de pointes: an overview

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12 December 2020

Case report: pentamidine and polymorphic ventricular tachycardia revisited

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12 December 2020

Risk of torsades de pointes with non-cardiac drugs. Prolongation of QT interval is probably a class effect of fluoroquinolones

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12 December 2020

Torsade de pointes and cardiorespiratory arrest induced by azithromycin in a patient with congenital long QT syndrome

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12 December 2020

Torsades de pointe probably related to sparfloxacin

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12 December 2020

Erythromycin-induced long QT syndrome: concordance with quinidine and underlying cellular electrophysiologic mechanism

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12 December 2020

Torsades de pointes due to drug interaction between disopyramide and clarithromycin

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12 December 2020

Torsade de pointes due to quinidine: observations in 31 patients

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12 December 2020

QTc interval in the assessment of cardiac risk

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12 December 2020

Proarrhythmia with class III antiarrhythmic drugs: types, risks, and management

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12 December 2020

Moxifloxacin does increase the corrected QT interval

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12 December 2020

A structural basis for drug-induced long QT syndrome

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12 December 2020

Preclinical safety evaluation of moxifloxacin, a novel fluoroquinolone

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12 December 2020

Use of terfenadine and contraindicated drugs

1 reference

12 December 2020

QT interval prolongation and torsades de pointes due to erythromycin lactobionate

1 reference

12 December 2020

Systemic antifungal agents. Drug interactions of clinical significance

1 reference

12 December 2020

Rates of torsades de pointes associated with ciprofloxacin, ofloxacin, levofloxacin, gatifloxacin, and moxifloxacin

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12 December 2020

Risk assessment for antimicrobial agent-induced QTc interval prolongation and torsades de pointes

1 reference

12 December 2020

A review of erythromycin-induced malignant tachyarrhythmia--torsade de pointes. A case report

1 reference

12 December 2020

Sparfloxacin but not levofloxacin or ofloxacin prolongs cardiac repolarization in rabbit Purkinje fibers

1 reference

12 December 2020

Incidence of cardiac arrhythmias during intravenous pentamidine therapy in HIV-infected patients

1 reference

12 December 2020

Pentamidine-induced torsade de pointes

1 reference

12 December 2020

Roxithromycin induced torsade de pointes in a patient with complex congenital heart disease and complete atrioventricular block

1 reference

12 December 2020

Hypokalemia-induced long QT syndrome with an underlying novel missense mutation in S4-S5 linker of KCNQ1

1 reference

12 December 2020

Syncopes during simultaneous use of terfenadine and itraconazole

1 reference

12 December 2020

Adverse drug reactions related to the use of fluoroquinolone antimicrobials: an analysis of spontaneous reports and fluoroquinolone consumption data from three italian regions.

1 reference

12 December 2020

Cardiotoxicity of macrolides, ketolides and fluoroquinolones that prolong the QTc interval

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12 December 2020

Blockade of HERG and Kv1.5 by ketoconazole

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12 December 2020

Ventricular tachycardia with 2 variable opposing foci

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12 December 2020

Ventricular fibrillation due to long QT syndrome probably caused by clindamycin

1 reference

12 December 2020

QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience

1 reference

12 December 2020

Voriconazole -- better chances for patients with invasive mycoses.

1 reference

12 December 2020

Clinical use of the fluoroquinolones

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12 December 2020

QUINIDINE SYNCOPE. PAROXYSMAL VENTRICULAR FIBRILLATION OCCURRING DURING TREATMENT OF CHRONIC ATRIAL ARRHYTHMIAS.

1 reference

12 December 2020

Effect of single ascending, supratherapeutic doses of sparfloxacin on cardiac repolarization (QTc interval)

1 reference

12 December 2020

Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes

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12 December 2020

Novel insights in the congenital long QT syndrome

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12 December 2020

The long QT syndromes: genetic basis and clinical implications

1 reference

12 December 2020

Structure-activity and structure-side-effect relationships for the quinolone antibacterials

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12 December 2020

[Torsades de pointe with spiramycine and metiquazine therapy. Apropos of a case]

1 reference

12 December 2020

Recurrent ventricular tachycardia due to pentamidine-induced cardiotoxicity

1 reference

12 December 2020

QT prolongation due to roxithromycin.

1 reference

12 December 2020

QT prolongation and torsades de pointes after administration of trimethoprim-sulfamethoxazole

1 reference

12 December 2020

Clinical significance of the cytochrome P450 2C19 genetic polymorphism

1 reference

12 December 2020

Life-threatening interaction between clarithromycin and disopyramide

1 reference

12 December 2020

Prescription of QT-prolonging drugs in a cohort of about 5 million outpatients

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12 December 2020

Psychotropic drugs, cardiac arrhythmia, and sudden death

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12 December 2020

Combined use of astemizole and ketoconazole resulting in torsade de pointes

1 reference

12 December 2020

"Optimum" formulae for heart rate correction of the QT interval.

1 reference

12 December 2020

Torsade de pointes: the long-short initiating sequence and other clinical features: observations in 32 patients

1 reference

12 December 2020

Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6).

1 reference

12 December 2020

The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: clinical and regulatory implications. Report on a policy conference of the European Society of Cardiology

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12 December 2020

Effects of fluoroquinolones on HERG currents

1 reference

12 December 2020

Intersubject and dose-related variability after intravenous administration of erythromycin.

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12 December 2020

A common polymorphism associated with antibiotic-induced cardiac arrhythmia

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12 December 2020

QT prolongation associated with azithromycin/amiodarone combination

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12 December 2020

Epidemiology and unique aspects of aging and infectious diseases

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12 December 2020

Cardiac Arrest Associated With Combination Cisapride and Itraconazole Therapy

1 reference

12 December 2020

Concurrent use of selected agents with moxifloxacin: an examination of labeling compliance within 1 year of marketing

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12 December 2020

QT prolongation and Torsades de Pointes associated with clarithromycin

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12 December 2020

Diurnal pattern of QTc interval: how long is prolonged? Possible relation to circadian triggers of cardiovascular events.

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12 December 2020

New antibiotics in pulmonary and critical care medicine: focus on advanced generation quinolones and cephalosporins

1 reference

12 December 2020

Ventricular tachycardia and torsades de pointes complicating pentamidine therapy of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome

1 reference

12 December 2020

Drug-induced prolongation of the QT interval

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12 December 2020

Beat-to-beat repolarization lability identifies patients at risk for sudden cardiac death

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12 December 2020

Fluconazole- and levofloxacin-induced torsades de pointes in an intensive care unit patient.

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12 December 2020

Torsades de Pointes after treatment with terfenadine and ketoconazole

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12 December 2020

Levofloxacin induced polymorphic ventricular tachycardia with normal QT interval

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12 December 2020

Measurement of the QT interval and the risk associated with QTc interval prolongation: a review

1 reference

12 December 2020

Safety profile of grepafloxacin compared with other fluoroquinolones

1 reference

12 December 2020

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

1 reference

12 December 2020

A new cause of torsades de pointes: combination of terfenadine and troleandomycin

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12 December 2020

Gatifloxacin-associated corrected QT interval prolongation, torsades de pointes, and ventricular fibrillation in patients with known risk factors

1 reference

12 December 2020

Safety profile of the quinolones

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12 December 2020

Effects of antiarrhythmic drugs on QT interval dispersion--relationship to antiarrhythmic action and proarrhythmia

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12 December 2020

Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 1997.

1 reference

12 December 2020

Pentamidine-induced torsades de pointes: safe completion of therapy with inhaled pentamidine

1 reference

12 December 2020

The QT interval and torsade de pointes

1 reference

12 December 2020

Taking the "idio" out of "idiosyncratic": predicting torsades de pointes

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12 December 2020

Electrophysiological mechanisms in a canine model of erythromycin-associated long QT syndrome

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12 December 2020

Torsades de pointes during intravenous pentamidine isethionate therapy

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12 December 2020

Effect of single and repeated oral doses of telithromycin on cardiac QT interval in healthy subjects

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12 December 2020

Contraindicated use of cisapride: impact of food and drug administration regulatory action

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12 December 2020

Pharmacokinetics and safety of voriconazole following intravenous- to oral-dose escalation regimens

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12 December 2020

Optimizing antimicrobial dosing in the critically ill patient

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12 December 2020

Cardiac repolarization: current knowledge, critical gaps, and new approaches to drug development and patient management

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12 December 2020

Torsade de pointes during administration of pentamidine isethionate

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12 December 2020

Clarithromycin-induced ventricular tachycardia

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12 December 2020

Repeated consumption of grapefruit juice considerably increases plasma concentrations of cisapride

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12 December 2020

Recent advances: the cytochrome P450 enzymes.

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12 December 2020

Clarithromycin associated with torsades de pointes

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12 December 2020

Review of macrolides and ketolides: focus on respiratory tract infections

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12 December 2020

Torsades de pointes in two chronic renal failure patients treated with cisapride and clarithromycin

1 reference

12 December 2020

Studies on the mechanism of a fatal clarithromycin-pimozide interaction in a patient with Tourette syndrome

1 reference

12 December 2020

Probable case of torsades de pointes induced by fluconazole

1 reference

12 December 2020

Comparative pharmacodynamic analysis of Q-T interval prolongation induced by the macrolides clarithromycin, roxithromycin, and azithromycin in rats

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12 December 2020

QT-interval prolonging drugs: mechanisms and clinical relevance of their arrhythmogenic hazards

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12 December 2020

Prolonged QT interval and torsades de pointes caused by the combination of fluconazole and amitriptyline

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12 December 2020

Itraconazole prevents terfenadine metabolism and increases risk of torsades de pointes ventricular tachycardia

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12 December 2020

Torsades de pointes ventricular tachycardia induced by clarithromycin and disopyramide in the presence of hypokalemia

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12 December 2020

Comparative tolerability of the newer fluoroquinolone antibacterials

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12 December 2020

Ventricular tachycardia due to pentamidine isethionate.

1 reference

12 December 2020

Quinolone-induced QT interval prolongation: a not-so-unexpected class effect

1 reference

12 December 2020

The inherited long QT syndrome: from ion channel to bedside

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12 December 2020

Hypomagnesemic torsades de pointes

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12 December 2020

Risk stratification in the long-QT syndrome.

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12 December 2020

Risk factors as reflected by an intensive drug monitoring system

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12 December 2020

The Sicilian gambit. A new approach to the classification of antiarrhythmic drugs based on their actions on arrhythmogenic mechanisms. Task Force of the Working Group on Arrhythmias of the European Society of Cardiology

1 reference

12 December 2020

Gatifloxacin-induced QTc prolongation and ventricular tachycardia

1 reference

12 December 2020

Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: a call for consensus

1 reference

12 December 2020

Physician-induced torsade de pointes--therapeutic implications.

1 reference

12 December 2020

What Clinicians Should Know About the QT Interval

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12 December 2020

Long QT syndromes and torsade de pointes

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12 December 2020

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

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12 December 2020

QT prolongation and torsades de pointes associated with concurrent use of cisapride and erythromycin

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12 December 2020

Torsades de pointes occurring in association with terfenadine use

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12 December 2020

Incidence and clinical features of the quinidine-associated long QT syndrome: implications for patient care

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12 December 2020

Quinolone-induced QT interval prolongation: a not-so-unexpected class effect

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12 December 2020

Interactions of a series of fluoroquinolone antibacterial drugs with the human cardiac K+ channel HERG.

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12 December 2020

How to measure the QT interval--what is normal?

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12 December 2020

Ciprofloxacin-induced QTc prolongation.

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12 December 2020

Concomitant risk factors in reports of torsades de pointes associated with macrolide use: review of the United States Food and Drug Administration Adverse Event Reporting System

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12 December 2020

Toxicity of quinolones

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12 December 2020

Potassium current antagonist properties and proarrhythmic consequences of quinolone antibiotics.

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12 December 2020

Measurement and interpretation of QT dispersion.

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12 December 2020

QTc-interval prolongation associated with slow intravenous erythromycin lactobionate infusions in critically ill patients: a prospective evaluation and review of the literature

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12 December 2020

Blockade of human cardiac potassium channel human ether-a-go-go-related gene (HERG) by macrolide antibiotics

1 reference

12 December 2020

Effect of coronary ischemia on QT dispersion

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12 December 2020

Ventricular tachycardia and long QT associated with clarithromycin administration in a patient with HIV infection

1 reference

12 December 2020

The long QT interval is not only inherited but is also linked to cardiac hypertrophy

1 reference

12 December 2020

Quinolone-induced QT interval prolongation: a not-so-unexpected class effect

1 reference

12 December 2020

Adverse drug events in hospitalized patients. Excess length of stay, extra costs, and attributable mortality.

1 reference

12 December 2020

QT interval: a measure of drug action

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12 December 2020

Antimicrobial-Drug Prescription in Ambulatory Care Settings, United States, 1992–2000

1 reference

12 December 2020

Torsade de pointes induced by cisapride/clarithromycin interaction

1 reference

12 December 2020

Comparison of bactericidal activity after multidose administration of clarithromycin, azithromycin, and ceruroxime axetil against Streptococcus pneumoniae.

1 reference

12 December 2020

The influence of cisapride and clarithromycin on QT intervals in healthy volunteers.

1 reference

12 December 2020

An overview of class III electrophysiological agents: a new generation of antiarrhythmic therapy

1 reference

12 December 2020

Torsade de pointes. Mechanisms and management.

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12 December 2020

Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling

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12 December 2020

The macrolides: erythromycin, clarithromycin, and azithromycin

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12 December 2020

Antimicrobial pharmacodynamics.

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12 December 2020

Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences

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12 December 2020

Torsades de pointes associated with fluoroquinolones: importance of concomitant risk factors

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12 December 2020

Sex difference in risk of torsade de pointes with d,l-sotalol

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12 December 2020

QT prolongation and paroxysmal ventricular tachycardia occurring during fever following trimethoprim-sulfamethoxazole administration

1 reference

12 December 2020

[A case of pulmonary aspergillosis effectively treated with itraconazole. Possible interaction of the antimycotic agent with hydroquinidine]

1 reference

12 December 2020

Azithromycin and terfenadine: lack of drug interaction.

1 reference

12 December 2020

Torsades de pointes associated with fluoroquinolones

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12 December 2020

Fluconazole-induced torsade de pointes

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12 December 2020

Long QT syndrome and torsade de pointes in a patient receiving fluconazole

1 reference

12 December 2020

10.2165/00003495-200464100-00005

Identifiers

DOI

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PubMed ID

15139788

Dimensions Publication ID

10 August 2017

0 references

1 reference

PubMed ID

15139788