(Q35772868)

10 August 2017

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title

The roles of the new negative T cell costimulatory pathways in regulating autoimmunity (English)

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10 August 2017

Samia J Khoury

1

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author name string

Mohamed H Sayegh

series ordinal

2

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PubMed ID

15142522

10 August 2017

language of work or name

English

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publication date

1 May 2004

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10 August 2017

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10 August 2017

20

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10 August 2017

5

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10 August 2017

529-538

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Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes

10 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Cutting edge: transplantation tolerance through enhanced CTLA-4 expression

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CD4+CD25high regulatory cells in human peripheral blood

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Viewpoint: therapeutic implications of CTLA-4 compartmentalization

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CD28-independent induction of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Genomic Organization and Expression Analysis of B7-H4, an Immune Inhibitory Molecule of the B7 Family

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

B7-H1 pathway and its role in the evasion of tumor immunity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CTLA-4 up-regulation plays a role in tolerance mediated by CD45.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Stimulating PD-1???negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152).

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Development and applications of surface-linked single chain antibodies against T-cell antigens

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

PD-1 inhibits antiviral immunity at the effector phase in the liver

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Blockade of B7-H1 Suppresses the Development of Chronic Intestinal Inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CTLA4 is associated with susceptibility to multiple sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CTLA-4: a negative regulator of autoimmune disease.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Fingerprints of anergic T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Regulation of PD‐1, PD‐L1, and PD‐L2 expression during normal and autoimmune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

B7-DC regulates asthmatic response by an IFN-gamma-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

ICOS is critical for CD40-mediated antibody class switching

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

A native soluble form of CTLA-4

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Programmed death-1 targeting can promote allograft survival

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Immune inhibitory receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

New B7 family members with positive and negative costimulatory function

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Association of the CTLA4 3' untranslated region polymorphism with the susceptibility to rheumatoid arthritis.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

T-cell costimulatory pathways in allograft rejection and tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The B7-CD28 superfamily

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Structure and chromosomal localization of the human PD-1 gene (PDCD1)

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CD150 association with either the SH2-containing inositol phosphatase or the SH2-containing protein tyrosine phosphatase is regulated by the adaptor protein SH2D1A

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Physiological mechanisms of regulating alloimmunity: cytokines, CTLA-4, CD25+ cells, and the alloreactive T cell clone size

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

B7-H4, a molecule of the B7 family, negatively regulates T cell immunity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Characterization of mouse and human B7-H3 genes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Mouse B7-H3 induces antitumor immunity.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Immunology of B7-H1 and its roles in human diseases

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Homeostasis and self-tolerance in the immune system: turning lymphocytes off.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CTLA-4 can function as a negative regulator of T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

CTLA-4 ligation blocks CD28-dependent T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Expression of programmed death 1 ligands by murine T cells and APC

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

T-cell co-stimulation through B7RP-1 and ICOS

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

Structural and functional analysis of the costimulatory receptor programmed death-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2804%2900116-5

7 January 2021

10.1016/S1074-7613(04)00116-5

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15142522