(Q35777950)

10 August 2017

title

Systematic synergy modeling: understanding drug synergy from a systems biology perspective (English)

1 reference

10 August 2017

1 reference

Di Chen

1

1 reference

10 August 2017

Xi Liu

2

1 reference

10 August 2017

Yiping Yang

3

1 reference

10 August 2017

Hongjun Yang

4

1 reference

10 August 2017

Peng Lu

5

1 reference

10 August 2017

publication date

16 September 2015

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10 August 2017

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10 August 2017

volume

9

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10 August 2017

page(s)

56

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Creative Commons Attribution 4.0 International

10 August 2017

copyright license

start time

16 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Multi-target therapeutics: when the whole is greater than the sum of the parts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

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27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

The efficiency of multi-target drugs: the network approach might help drug design

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Network motifs: simple building blocks of complex networks

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

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27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

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27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

PPI network analysis of mRNA expression profile of ezrin knockdown in esophageal squamous cell carcinoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

The dynamics of p53 in single cells: physiologically based ODE and reaction-diffusion PDE models

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

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25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Network-based target ranking for polypharmacological therapies.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Hybrid modeling of the crosstalk between signaling and transcriptional networks using ordinary differential equations and multi-valued logic

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Biological network motif detection: principles and practice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Prediction of drug combinations by integrating molecular and pharmacological data

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

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25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Network modeling of MDM2 inhibitor-oxaliplatin combination reveals biological synergy in wt-p53 solid tumors

25 September 2018

1 reference

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A systems biology approach to identify effective cocktail drugs

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Discovering causal signaling pathways through gene-expression patterns

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Drug combination studies and their synergy quantification using the Chou-Talalay method

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Comparing different ODE modelling approaches for gene regulatory networks.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4574089

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25 September 2018

1 reference

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NetCAD: a network analysis tool for coronary artery disease-associated PPI network

25 September 2018

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The problem of synergism and antagonism of combined drugs

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12 December 2020

Mechanisms of drug combinations: interaction and network perspectives

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DCDB: drug combination database

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Novel HIV-1 treatment Stribild™ gains regulatory approval

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A mathematical model of combination therapy using the EGFR signaling network

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Identifiers

DOI

1 reference

journals/bmcsb/ChenLYYL15

10 August 2017

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

Dimensions Publication ID

28 January 2021

0 references

1 reference

10 August 2017

1 reference