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Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
title
Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
main subject
pharmacology
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inferred from title
author
Giulio Superti-Furga
series ordinal
14
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Florian Grebien
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Florian P Breitwieser
series ordinal
8
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Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Martin Bilban
series ordinal
9
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Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Jacques Colinge
series ordinal
10
1 reference
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Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Peter Valent
series ordinal
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Forest M. White
series ordinal
13
1 reference
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Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Keiryn L Bennett
series ordinal
12
object named as
Keiryn L Bennett
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Manuela Gridling
series ordinal
6
object named as
Manuela Gridling
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Uwe Rix
series ordinal
2
object named as
Uwe Rix
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
author name string
Georg E Winter
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Scott M Carlson
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Karoline V Gleixner
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
André C Müller
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
publication date
30 September 2012
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stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
published in
Nature Chemical Biology
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
volume
8
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
page(s)
905-912
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nchembio.1085
0 references
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Seeking the causes and solutions to imatinib-resistance in chronic myeloid leukemia
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10 September 2017
The challenges of integrating multi-omic data sets
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10 September 2017
Selective inhibition of BET bromodomains
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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10 September 2017
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PubMed Central
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AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
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10 September 2017
Highly parallel identification of essential genes in cancer cells
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10 September 2017
Reflecting on 25 years with MYC.
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PubMed Central
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10 September 2017
Network pharmacology: the next paradigm in drug discovery
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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10 September 2017
Molecular biology of bcr-abl1-positive chronic myeloid leukemia
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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10 September 2017
Activation of tyrosine kinases by mutation of the gatekeeper threonine
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10 September 2017
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease
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10 September 2017
Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function
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10 September 2017
Kinase domain mutants of Bcr-Abl exhibit altered transformation potency, kinase activity, and substrate utilization, irrespective of sensitivity to imatinib
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10 September 2017
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10 September 2017
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10 September 2017
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10 September 2017
Imatinib as a paradigm of targeted therapies
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10 September 2017
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10 September 2017
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10 September 2017
c-MYC: more than just a matter of life and death
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10 September 2017
The transcriptional program of a human B cell line in response to Myc
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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10 September 2017
Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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10 September 2017
A phosphorylation site located in the NH2-terminal domain of c-Myc increases transactivation of gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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10 September 2017
BCR-ABL uncouples canonical JAK2-STAT5 signaling in chronic myeloid leukemia
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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10 September 2017
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib.
1 reference
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PubMed Central
reference URL
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14 September 2017
Synergistic drug combinations tend to improve therapeutically relevant selectivity
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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14 September 2017
Imatinib mesylate resistance through BCR-ABL independence in chronic myelogenous leukemia
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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14 September 2017
Selection and characterization of BCR-ABL positive cell lines with differential sensitivity to the tyrosine kinase inhibitor STI571: diverse mechanisms of resistance.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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25 September 2017
A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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17 June 2018
Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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17 June 2018
Dominant negative MYC blocks transformation by ABL oncogenes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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17 June 2018
c-Myc phosphorylation is required for cellular response to oxidative stress
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4038039
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21 August 2018
Cancer as a robust system: implications for anticancer therapy
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23023260
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Phylogenetic Reconstruction Using an Unsupervised Growing Neural Network That Adopts the Topology of a Phylogenetic Tree
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23023260
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/NCHEMBIO.1085
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PMC publication ID
4038039
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PubMed publication ID
23023260
1 reference
stated in
Europe PubMed Central
PMC publication ID
4038039
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23023260%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
ResearchGate publication ID
231612952
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