(Q35779256)

English

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

scientific article published on 8 February 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

Debyani Chakravarty

3

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Europe PubMed Central

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10 August 2017

Cameron Brennan

13

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Europe PubMed Central

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10 August 2017

12

object named as

Tom Mikkelsen

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Europe PubMed Central

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10 August 2017

9

object named as

Jason T Huse

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Europe PubMed Central

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10 August 2017

10

object named as

Suresh Jhanwar

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Europe PubMed Central

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10 August 2017

Nicholas J Szerlip

1

object named as

Nicholas J Szerlip

1 reference

Europe PubMed Central

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10 August 2017

8

object named as

Eric C Holland

1 reference

Europe PubMed Central

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10 August 2017

author name string

Alicia Pedraza

2

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Europe PubMed Central

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10 August 2017

Mohammad Azim

4

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Europe PubMed Central

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10 August 2017

Jeremy McGuire

5

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Europe PubMed Central

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10 August 2017

Yuqiang Fang

6

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Europe PubMed Central

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10 August 2017

Tatsuya Ozawa

7

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Europe PubMed Central

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10 August 2017

Margaret A Leversha

11

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10 August 2017

language of work or name

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publication date

8 February 2012

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Europe PubMed Central

PubMed publication ID

10 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

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10 August 2017

109

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Europe PubMed Central

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10 August 2017

8

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Europe PubMed Central

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10 August 2017

3041-3046

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Recruited cells can become transformed and overtake PDGF-induced murine gliomas in vivo during tumor progression

1 reference

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Brain tumor microvesicles: insights into intercellular communication in the nervous system

1 reference

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Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib--a phase II trial

1 reference

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SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans

1 reference

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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

1 reference

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Glioblastoma-derived spheroid cultures as an experimental model for analysis of EGFR anomalies.

1 reference

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Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

1 reference

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Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies

1 reference

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A phase II trial of erlotinib in patients with recurrent malignant gliomas and nonprogressive glioblastoma multiforme postradiation therapy

1 reference

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

1 reference

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Inferring tumor progression from genomic heterogeneity

1 reference

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Expression, mutation and copy number analysis of platelet-derived growth factor receptor A (PDGFRA) and its ligand PDGFA in gliomas.

1 reference

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An efficient method for derivation and propagation of glioblastoma cell lines that conserves the molecular profile of their original tumours

1 reference

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Phase II study of imatinib in patients with recurrent gliomas of various histologies: a European Organisation for Research and Treatment of Cancer Brain Tumor Group Study

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Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium

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Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

1 reference

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Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development

1 reference

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Malignant astrocytic glioma: genetics, biology, and paths to treatment

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

1 reference

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Patient tumor EGFR and PDGFRA gene amplifications retained in an invasive intracranial xenograft model of glioblastoma multiforme

1 reference

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Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR

1 reference

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Growth factor profiles of human gliomas. Do non-tumour cells contribute to tumour growth in glioma?

1 reference

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

1 reference

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Mathematical models of gene amplification with applications to cellular drug resistance and tumorigenicity

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Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.

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Karyotypes in 90 human gliomas

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PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

1 reference

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1 reference

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1 reference

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1 reference

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Selection pressures of TP53 mutation and microenvironmental location influence epidermal growth factor receptor gene amplification in human glioblastomas.

1 reference

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Identifiers

10.1073/PNAS.1114033109

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

2012PNAS..109.3041S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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