(Q35782195)

English

The role of Fas ligand and transforming growth factor beta in tumor progression: molecular mechanisms of immune privilege via Fas-mediated apoptosis and potential targets for cancer therapy

scientific article published on June 2004

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

Europe PubMed Central

The role of Fas ligand and transforming growth factor beta in tumor progression: molecular mechanisms of immune privilege via Fas-mediated apoptosis and potential targets for cancer therapy (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

apoptotic process

1 reference

based on heuristic

inferred from title

tumor progression

1 reference

based on heuristic

inferred from title

author name string

Ryungsa Kim

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Manabu Emi

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Kazuaki Tanabe

3

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Yoko Uchida

4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Tetsuya Toge

5

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

language of work or name

0 references

publication date

1 June 2004

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

100

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

11

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

2281-2291

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

21 January 2018

Transforming growth factor beta enhances epithelial cell survival via Akt-dependent regulation of FKHRL1

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

21 January 2018

Expressions of Fas ligand and other apoptosis-related genes and their prognostic significance in epithelial ovarian neoplasms

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

21 January 2018

The prognostic molecular markers in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

21 January 2018

Frequent deletion of Fas gene sequences encoding death and transmembrane domains in nasal natural killer/T-cell lymphoma.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

21 January 2018

Alterations of Fas (Apo-1/CD95) gene in cutaneous malignant melanoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

21 January 2018

Angiogenesis and apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

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Current status of the molecular mechanisms of anticancer drug-induced apoptosis. The contribution of molecular-level analysis to cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

The biological role of the Fas/FasL system during tumor formation and progression

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation-induced cell death in T cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Signal transduction by the TGF-beta superfamily

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

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TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

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Defective apoptosis and tumorigenesis: role of p53 mutation and Fas/FasL system dysregulation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of functional Fas ligand in choriocarcinoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas and Fas ligand: expression and soluble circulating levels in cutaneous malignant melanoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas ligand expression in Hodgkin lymphoma.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas ligand expression is correlated with metastasis in colorectal carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

CD95 ligand expression as a mechanism of immune escape in breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

A docking model of key components of the DISC complex: death domain superfamily interactions redefined

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Genealogy, expression, and cellular function of transforming growth factor-β

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Active transcriptional repression by the Rb-E2F complex mediates G1 arrest triggered by p16INK4a, TGFbeta, and contact inhibition

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Transforming growth factor beta 1 induces proliferation in colon carcinoma cells by Ras-dependent, smad-independent down-regulation of p21cip1.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Consequences of altered TGF-beta expression and responsiveness in breast cancer: evidence for autocrine and paracrine effects.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Disruption of TGFbeta signaling pathways in human pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Alternative genetic pathways in colorectal carcinogenesis.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumorigenesis in colorectal tumors from patients with hereditary non-polyposis colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that Smad2 is a tumor suppressor implicated in the control of cellular invasion

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Infrequent mutation of the tumour-suppressor gene Smad4 in early-stage colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Elevated serum levels of transforming growth factor-beta1 in patients with colorectal carcinoma: its association with tumor progression and its significant decrease after curative surgical resection

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-2 overexpression inhibits cell death and promotes the morphogenesis, but not tumorigenesis of human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas ligand-induced apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor-induced death of immune cells: its mechanisms and consequences

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas ligand upregulation is an early event in colonic carcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of Fas ligand in liver metastases of human colonic adenocarcinomas

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Resistance to Fas (APO-1/CD95)-mediated apoptosis and expression of Fas ligand in esophageal cancer: the Fas counterattack

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Circulating soluble Fas ligand in patients with gastric carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of Fas ligand by human gastric adenocarcinomas: a potential mechanism of immune escape in stomach cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas receptor counterattack against tumor-infiltrating lymphocytes in vivo as a mechanism of immune escape in gastric carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic relevance of altered Fas (CD95)-system in human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of the proinflammatory effects of Fas ligand (CD95L).

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Frameshift mutations in Fas, Apaf-1 and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumour hypoxia, chemotherapeutic resistance and hypoxia-related therapies.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Transforming growth factor beta1 inhibits Fas ligand expression and subsequent activation-induced cell death in T cells via downregulation of c-Myc

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Macrophages in tumor-draining lymph node with different characteristics induce T-cell apoptosis in patients with advanced stage-gastric cancer.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis of immune cells in the tumor microenvironment and peripheral circulation of patients with cancer: implications for immunotherapy

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

The amplification of TCR signaling by dynamic membrane microdomains

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined intraarterial 5-fluorouracil and subcutaneous interferon-alpha therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Integration of interferon-alpha/beta signalling to p53 responses in tumour suppression and antiviral defence.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Chemotherapeutic agents sensitize osteogenic sarcoma cells, but not normal human bone cells, to Apo2L/TRAIL-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas and Fas ligand in gut and liver

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

A phase 2 study of bortezomib in relapsed, refractory myeloma

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Development of the proteasome inhibitor PS-341.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor immunology--towards a paradigm of reciprocal research

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

A role for a novel luminal endoplasmic reticulum aminopeptidase in final trimming of 26 S proteasome-generated major histocompatability complex class I antigenic peptides

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Autocrine transforming growth factor-beta signaling mediates Smad-independent motility in human cancer cells.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of anti-TGF-beta2 antibody as a new postoperative anti-scarring agent in glaucoma surgery.

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Anti-transforming growth factor (TGF)-beta antibodies inhibit breast cancer cell tumorigenicity and increase mouse spleen natural killer cell activity. Implications for a possible role of tumor cell/host TGF-beta interactions in human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.20270

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CNCR.20270

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

0 references

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