(Q35788756)

English

SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of "cancer cells with neural stemness" in a p53-dependent manner.

scientific article published on 5 August 2014

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scholarly article

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12 March 2020

SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of "cancer cells with neural stemness" in a p53-dependent manner (English)

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12 March 2020

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neural stem cell

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inferred from title

11

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12 March 2020

author name string

Ji-Seon Lee

1

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12 March 2020

Jeong-Rak Park

2

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12 March 2020

Ok-Seon Kwon

3

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12 March 2020

Tae-Hee Lee

4

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12 March 2020

Ichiro Nakano

5

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12 March 2020

Hiroyuki Miyoshi

6

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12 March 2020

Kwang-Hoon Chun

7

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12 March 2020

Myung-Jin Park

8

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12 March 2020

Hong Jun Lee

9

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12 March 2020

Seung U Kim

10

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12 March 2020

publication date

5 August 2014

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12 March 2020

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12 March 2020

17

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12 March 2020

1

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12 March 2020

95-106

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12 March 2020

describes a project that uses

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0 references

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4483050/fullTextXML

based on heuristic

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Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3.

1 reference

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Establishment of immortalized human erythroid progenitor cell lines able to produce enucleated red blood cells

1 reference

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12 July 2018

MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells.

1 reference

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12 July 2018

Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner

1 reference

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12 July 2018

WIP1 phosphatase modulates the Hedgehog signaling by enhancing GLI1 function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

SIRT1 promotes proliferation and inhibits apoptosis of human malignant glioma cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Activation of p53 by SIRT1 inhibition enhances elimination of CML leukemia stem cells in combination with imatinib

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Regulation of the Wip1 phosphatase and its effects on the stress response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Sirt1 overexpression in neurons promotes neurite outgrowth and cell survival through inhibition of the mTOR signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Generation of cancerous neural stem cells forming glial tumor by oncogenic stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

SIRT inhibitors induce cell death and p53 acetylation through targeting both SIRT1 and SIRT2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

1 reference

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12 July 2018

Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

p53 acetylation is crucial for its transcription-independent proapoptotic functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

SIRT1, is it a tumor promoter or tumor suppressor?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

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Enhanced radiosensitivity and radiation-induced apoptosis in glioma CD133-positive cells by knockdown of SirT1 expression

1 reference

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12 July 2018

Crypt stem cells as the cells-of-origin of intestinal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Acetylation is indispensable for p53 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Many roads lead to oncogene-induced senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

RB and cyclin dependent kinase pathways: defining a distinction between RB and p16 loss in lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

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hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

Negative control of p53 by Sir2alpha promotes cell survival under stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

12 July 2018

The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression

1 reference

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Tumor suppressors and oncogenes in cellular senescence.

1 reference

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The Hallmarks of Cancer

1 reference

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A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer

1 reference

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25 September 2018

Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

25 September 2018

Sirt1 contributes critically to the redox-dependent fate of neural progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4483050

25 September 2018

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles

1 reference

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25 September 2018

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1 reference

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The power and the promise of oncogene-induced senescence markers.

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A genetically tractable model of human glioma formation.

1 reference

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Engraftable human neural stem cells respond to developmental cues, replace neurons, and express foreign genes.

1 reference

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SirT1 fails to affect p53-mediated biological functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25096191

12 December 2020

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Identifiers

10.1093/NEUONC/NOU145

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25096191%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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12 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25096191%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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