(Q35789268)

10 August 2017

1 reference

title

Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development (English)

1 reference

malignant pleural mesothelioma

10 August 2017

1 reference

1 reference

Dean A Fennell

1

1 reference

PubMed ID

15172356

10 August 2017

Robin M Rudd

series ordinal

2

1 reference

10 August 2017

1 June 2004

1 reference

Lancet Oncology Commission

10 August 2017

1 reference

10 August 2017

5

1 reference

10 August 2017

354-362

1 reference

10 August 2017

6

1 reference

The European mesothelioma epidemic

10 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Phase II study of vinorelbine in patients with malignant pleural mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Apoptosis in development

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Apoptosis: a link between cancer genetics and chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Simian virus-40 large-T antigen binds p53 in human mesotheliomas.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

The retinoblastoma gene family pRb/p105, p107, pRb2/p130 and simian virus-40 large T-antigen in human mesotheliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Alterations of the p16(INK4) locus in human malignant mesothelial tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Bcl-2 resistant mitochondrial toxicity mediated by the isoquinoline carboxamide PK11195 involves de novo generation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Targeting Bcl-2 and Bcl-X with nonpeptidic small-molecule antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Conformation of the Bax C-terminus regulates subcellular location and cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Significant augmentation of pro-apoptotic gene therapy by pharmacologic bcl-xl down-regulation in mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

A high-throughput screen for identification of molecular mimics of Smac/DIABLO utilizing a fluorescence polarization assay.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

The permeability transition pore signals apoptosis by directing Bax translocation and multimerization.

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand and chemotherapy cooperate to induce apoptosis in mesothelioma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Induction of apoptosis in malignant pleural mesothelioma cells by activation of the Fas (Apo-1/CD95) death-signal pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Human normal hepatocytes are susceptible to apoptosis signal mediated by both TRAIL-R1 and TRAIL-R2

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Expression of growth factor and growth factor receptor RNA in rat pleural mesothelial cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

AKT and the phosphatidylinositol 3-kinase/AKT pathway: important molecular targets for lung cancer prevention and treatment

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Phosphatase and tensin analog gene overexpression engenders cellular death in human malignant mesothelioma cells via inhibition of AKT phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Malignant pleural mesothelioma and epidermal growth factor receptor (EGF-R). Relationship of EGF-R with histology and survival using fixed paraffin embedded tissue and the F4, monoclonal antibody

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Immunohistochemical distribution patterns of epidermal growth factor receptor in malignant mesothelioma and non-neoplastic mesothelium

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Increased expression of epidermal growth factor receptor in rat pleural mesothelial cells correlates with carcinogenicity of mineral fibres

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Growth factor responses and protooncogene expression of murine mesothelial cell lines derived from asbestos-induced mesotheliomas

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Manganese superoxide dismutase in human pleural mesothelioma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Manganese superoxide dismutase in healthy human pleural mesothelium and in malignant pleural mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Antioxidant defense mechanisms of human mesothelioma and lung adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Pk11195, a mitochondrial benzodiazepine receptor antagonist, reduces apoptosis threshold in Bcl-X(L) and Mcl-1 expressing human cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

Redox cycling by motexafin gadolinium enhances cellular response to ionizing radiation by forming reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2804%2901492-5

7 January 2021

10.1016/S1470-2045(04)01492-5

Identifiers

DOI

1 reference

10 August 2017

1 reference

PubMed ID

15172356