(Q35790360)

10 August 2017

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title

Adhesion mechanisms regulating the migration of monocytes (English)

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Gene Ontology release 2020-05-02

10 August 2017

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2

Michel Aurrand-Lions

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10 August 2017

Beat A Imhof

1

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10 August 2017

1 June 2004

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Nature Reviews Immunology

10 August 2017

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10 August 2017

4

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10 August 2017

432-444

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10 August 2017

6

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Homing and cellular traffic in lymph nodes

10 August 2017

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The origin and kinetics of mononuclear phagocytes

31 March 2020

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The dendritic cell system and its role in immunogenicity

31 March 2020

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CD14+ blood monocytes can differentiate into functionally mature CD83+ dendritic cells

31 March 2020

1 reference

Characterization of a common precursor population for dendritic cells

31 March 2020

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Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo

31 March 2020

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Blood monocytes consist of two principal subsets with distinct migratory properties

31 March 2020

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Fractalkine preferentially mediates arrest and migration of CD16+ monocytes

31 March 2020

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In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen

31 March 2020

1 reference

Inflammatory chemokine transport and presentation in HEV: a remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues

31 March 2020

1 reference

Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment

31 March 2020

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Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

31 March 2020

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Defining the interleukin-8-binding domain of heparan sulfate

31 March 2020

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Interleukin-8 binds to syndecan-2 on human endothelial cells.

31 March 2020

1 reference

T-cell adhesion induced by proteoglycan-immobilized cytokine MIP-lβ

31 March 2020

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RANTES (CCL5) uses the proteoglycan CD44 as an auxiliary receptor to mediate cellular activation signals and HIV-1 enhancement

31 March 2020

1 reference

The strategy of blocking the chemokine system to combat disease

31 March 2020

1 reference

Dancing to the tune of chemokines

31 March 2020

1 reference

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

31 March 2020

1 reference

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

31 March 2020

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Rap1 signalling: adhering to new models

31 March 2020

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The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators

31 March 2020

1 reference

The Rap GTPases regulate integrin-mediated adhesion, cell spreading, actin polymerization, and Pyk2 tyrosine phosphorylation in B lymphocytes

31 March 2020

1 reference

Epac: a new cAMP target and new avenues in cAMP research

31 March 2020

1 reference

Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow

31 March 2020

1 reference

The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration

31 March 2020

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RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

31 March 2020

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Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

31 March 2020

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31 March 2020

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Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

31 March 2020

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Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

31 March 2020

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Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

31 March 2020

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Phosphorylation of beta3 integrin controls ligand binding strength

31 March 2020

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Role of the cytoplasmic tyrosines of beta 1A integrins in transformation by v-src

31 March 2020

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Activation of Rhoa and ROCK are essential for detachment of migrating leukocytes

31 March 2020

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Rapid leukocyte integrin activation by chemokines

31 March 2020

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RhoA and ROCK promote migration by limiting membrane protrusions

31 March 2020

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LFA-1-induced T cell migration on ICAM-1 involves regulation of MLCK-mediated attachment and ROCK-dependent detachment

31 March 2020

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RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing

31 March 2020

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Different regions of Rho determine Rho-selective binding of different classes of Rho target molecules.

31 March 2020

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Effectors for the Rho GTPases

31 March 2020

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Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain

31 March 2020

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Regulation of cell polarity and protrusion formation by targeting RhoA for degradation

31 March 2020

1 reference

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

31 March 2020

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Absence of marginal zone B cells in Pyk-2-deficient mice defines their role in the humoral response

31 March 2020

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RAFTK/Pyk2-mediated cellular signalling

31 March 2020

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Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration

31 March 2020

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Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

31 March 2020

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The inner lives of focal adhesions

31 March 2020

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Cell migration: integrating signals from front to back

31 March 2020

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Leukocyte polarization in cell migration and immune interactions

31 March 2020

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Cross talk between alpha(v)beta3 and alpha4beta1 integrins regulates lymphocyte migration on vascular cell adhesion molecule 1.

31 March 2020

1 reference

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

31 March 2020

1 reference

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

31 March 2020

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Forging the endothelium during inflammation: pushing at a half-open door?

31 March 2020

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Neutrophils emigrate from venules by a transendothelial cell pathway in response to FMLP

31 March 2020

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Leukocyte transendothelial migration: a junctional affair

31 March 2020

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Multifunctional strands in tight junctions

31 March 2020

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Junctional adhesion molecules (JAMs): more molecules with dual functions?

31 March 2020

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The JAM family of junctional adhesion molecules

31 March 2020

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Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration

31 March 2020

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A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets

31 March 2020

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JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes

31 March 2020

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Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin

31 March 2020

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Association of junctional adhesion molecule with calcium/calmodulin-dependent serine protein kinase (CASK/LIN-2) in human epithelial caco-2 cells

31 March 2020

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The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)

31 March 2020

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Reduced expression of junctional adhesion molecule and platelet/endothelial cell adhesion molecule-1 (CD31) at human vascular endothelial junctions by cytokines tumor necrosis factor-alpha plus interferon-gamma Does not reduce leukocyte transmigrati

31 March 2020

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JAM-2, a novel immunoglobulin superfamily molecule, expressed by endothelial and lymphatic cells

31 March 2020

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A novel protein with homology to the junctional adhesion molecule. Characterization of leukocyte interactions

31 March 2020

1 reference

Cloning of human junctional adhesion molecule 3 (JAM3) and its identification as the JAM2 counter-receptor

31 March 2020

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Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells

31 March 2020

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The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1

31 March 2020

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JAM2 interacts with alpha4beta1. Facilitation by JAM3

31 March 2020

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Junctional adhesion molecule-2 (JAM-2) promotes lymphocyte transendothelial migration

31 March 2020

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The Wnt signalling pathway

31 March 2020

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A novel endothelial-specific membrane protein is a marker of cell-cell contacts

31 March 2020

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Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis

31 March 2020

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Monocytes induce reversible focal changes in vascular endothelial cadherin complex during transendothelial migration under flow

31 March 2020

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Real-time imaging of vascular endothelial-cadherin during leukocyte transmigration across endothelium

31 March 2020

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Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis

31 March 2020

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PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis

31 March 2020

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PECAM-1 (CD31) homophilic interaction up-regulates alpha6beta1 on transmigrated neutrophils in vivo and plays a functional role in the ability of alpha6 integrins to mediate leukocyte migration through the perivascular basement membrane

31 March 2020

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CD99 plays a major role in the migration of monocytes through endothelial junctions

31 March 2020

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The last molecular fortress in leukocyte trans-endothelial migration

31 March 2020

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Gap junctions in human umbilical cord endothelial cells contain multiple connexins

31 March 2020

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Tumour necrosis factor alpha alters the expression of connexin43, connexin40, and connexin37 in human umbilical vein endothelial cells

31 March 2020

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TNF-alpha plus IFN-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses

31 March 2020

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Leukocytes express connexin 43 after activation with lipopolysaccharide and appear to form gap junctions with endothelial cells after ischemia-reperfusion.

31 March 2020

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Gap junction intercellular communication during lymphocyte transendothelial migration

31 March 2020

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Gap-junctional coupling between neutrophils and endothelial cells: a novel modulator of transendothelial migration

31 March 2020

1 reference

Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development

31 March 2020

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Mammalian defensins in immunity: more than just microbicidal

31 March 2020

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Many chemokines including CCL20/MIP-3alpha display antimicrobial activity.

31 March 2020

1 reference

The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Relationship between macrophages, Langerhans cells, reticular cells, and dendritic cells in lymphoid and hematopoietic organs.

31 March 2020

1 reference

Differentiation of dendritic cell populations in macrophage colony-stimulating factor-deficient mice homozygous for the osteopetrosis (op) mutation

31 March 2020

1 reference

Differential production of IL-12, IFN-alpha, and IFN-gamma by mouse dendritic cell subsets

31 March 2020

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Specific migratory dendritic cells rapidly transport antigen from the airways to the thoracic lymph nodes

31 March 2020

1 reference

The accumulation of dendritic cells in the lung is impaired in CD18-/- but not in ICAM-1-/- mutant mice

31 March 2020

1 reference

Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.

31 March 2020

1 reference

A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes

31 March 2020

1 reference

Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node

31 March 2020

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Tolerogenic dendritic cells

31 March 2020

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Differential chemokine receptor expression and function in human monocyte subpopulations

31 March 2020

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MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions

31 March 2020

1 reference

Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice

31 March 2020

1 reference

Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.

31 March 2020

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Defects in macrophage recruitment and host defense in mice lacking the CCR2 chemokine receptor

31 March 2020

1 reference

Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice

31 March 2020

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L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites

31 March 2020

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Rapid recruitment of inflammatory monocytes is independent of neutrophil migration

31 March 2020

1 reference

Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo

31 March 2020

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Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members

31 March 2020

1 reference

PECAM-1 is required for transendothelial migration of leukocytes

31 March 2020

1 reference

Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1

31 March 2020

1 reference

Soluble domain 1 of platelet-endothelial cell adhesion molecule (PECAM) is sufficient to block transendothelial migration in vitro and in vivo

31 March 2020

1 reference

Integrin activation by regulated dimerization and oligomerization of platelet endothelial cell adhesion molecule (PECAM)-1 from within the cell

31 March 2020

1 reference

A blast from the past: clearance of apoptotic cells regulates immune responses.

31 March 2020

1 reference

Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation

31 March 2020

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Differentiation of monocytes into dendritic cells in a model of transendothelial trafficking

31 March 2020

1 reference

The CD16(+) (FcgammaRIII(+)) subset of human monocytes preferentially becomes migratory dendritic cells in a model tissue setting

31 March 2020

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Mobilizing dendritic cells for tolerance, priming, and chronic inflammation

31 March 2020

1 reference

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

31 March 2020

1 reference

Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming

31 March 2020

1 reference

Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo

31 March 2020

1 reference

Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortex

31 March 2020

1 reference

Interaction of dendritic cells with skin endothelium: A new perspective on immunosurveillance

31 March 2020

1 reference

DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking.

31 March 2020

1 reference

Immature mouse dendritic cells enter inflamed tissue, a process that requires E- and P-selectin, but not P-selectin glycoprotein ligand 1.

31 March 2020

1 reference

Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice

31 March 2020

1 reference

The alpha4-integrin: an alternative pathway for neutrophil recruitment?

31 March 2020

1 reference

Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo

31 March 2020

1 reference

Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

31 March 2020

1 reference

Flow cytometric identification of murine neutrophils and monocytes.

31 March 2020

1 reference

Leukocyte migration and adhesion.

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Endogenous monocyte chemoattractant protein-1 recruits monocytes in the zymosan peritonitis model

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1375

1 reference

10 August 2017

1 reference

PubMed ID

15173832