(Q35790526)

English

High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation.

scientific article published on 28 September 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414661%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

High Fat Diet Enhances β-Site Cleavage of Amyloid Precursor Protein (APP) via Promoting β-Site APP Cleaving Enzyme 1/Adaptor Protein 2/Clathrin Complex Formation (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414661%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

11

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25 February 2020

12

object named as

Shun Shimohama

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25 February 2020

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Masato Maesako

1

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25 February 2020

Maiko Uemura

2

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25 February 2020

Yoshitaka Tashiro

3

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25 February 2020

Kazuki Sasaki

4

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25 February 2020

Kiwamu Watanabe

5

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25 February 2020

Yasuha Noda

6

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25 February 2020

Karin Ueda

7

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25 February 2020

Megumi Asada-Utsugi

8

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25 February 2020

Masakazu Kubota

9

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25 February 2020

Katsuya Okawa

10

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25 February 2020

Kengo Uemura

13

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25 February 2020

Ayae Kinoshita

14

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25 February 2020

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28 September 2015

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25 February 2020

1 reference

Europe PubMed Central

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25 February 2020

10

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Europe PubMed Central

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25 February 2020

9

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414661%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

e0131199

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25 February 2020

copyright license

Creative Commons Attribution 4.0 International

28 September 2015

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April 2022 Public Data File from Crossref

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0 references

Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

1 reference

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27 July 2018

Continuation of exercise is necessary to inhibit high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice

1 reference

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27 July 2018

Metabolic stress modulates Alzheimer's β-secretase gene transcription via SIRT1-PPARγ-PGC-1 in neurons

1 reference

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27 July 2018

Exercise is more effective than diet control in preventing high fat diet-induced β-amyloid deposition and memory deficit in amyloid precursor protein transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587376

27 July 2018

Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.

1 reference

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27 July 2018

Β-site APP-cleaving enzyme 1 trafficking and Alzheimer's disease pathogenesis

1 reference

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27 July 2018

Midlife overweight and obesity increase late-life dementia risk: a population-based twin study

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27 July 2018

Effect of glycogen synthase kinase 3 β-mediated presenilin 1 phosphorylation on amyloid β production is negatively regulated by insulin receptor cleavage

1 reference

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27 July 2018

Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice

1 reference

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27 July 2018

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

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The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged

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N-cadherin-based adhesion enhances Abeta release and decreases Abeta42/40 ratio

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Aggregation of vascular risk factors and risk of incident Alzheimer disease

1 reference

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27 July 2018

Memapsin 2 (beta-secretase) cytosolic domain binds to the VHS domains of GGA1 and GGA2: implications on the endocytosis mechanism of memapsin 2

1 reference

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27 July 2018

Characterization of the glycosylation profiles of Alzheimer's beta -secretase protein Asp-2 expressed in a variety of cell lines.

1 reference

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27 July 2018

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

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27 July 2018

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587376

27 July 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

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27 July 2018

Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4587376

27 July 2018

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

1 reference

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Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation

1 reference

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27 July 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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27 July 2018

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

1 reference

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27 July 2018

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

1 reference

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

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GSK3beta activity modifies the localization and function of presenilin 1.

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Protein organization in clathrin trimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/26414661

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced release of amyloid beta-protein from codon 670/671 "Swedish" mutant beta-amyloid precursor protein occurs in both secretory and endocytic pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/26414661

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0131199

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414661%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

2015PLoSO..1031199M

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Europe PubMed Central

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25 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26414661%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

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