(Q35790896)

10 August 2017

title

Inhibition of fatty acid oxidation enhances oxidative protein folding and protects hepatocytes from endoplasmic reticulum stress (English)

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10 August 2017

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endoplasmic reticulum

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protein folding

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author name string

Heather M Tyra

series ordinal

1

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10 August 2017

Douglas R Spitz

series ordinal

2

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10 August 2017

D Thomas Rutkowski

series ordinal

3

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10 August 2017

publication date

19 January 2012

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Molecular Biology of the Cell

10 August 2017

published in

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10 August 2017

volume

23

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10 August 2017

issue

5

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10 August 2017

page(s)

811-819

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Sustained activation of PPARα by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice

10 August 2017

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Progressive endoplasmic reticulum stress contributes to hepatocarcinogenesis in fatty acyl-CoA oxidase 1-deficient mice

12 July 2018

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12 July 2018

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12 July 2018

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Induction of liver steatosis and lipid droplet formation in ATF6alpha-knockout mice burdened with pharmacological endoplasmic reticulum stress

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver

12 July 2018

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Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice

12 July 2018

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Role of ERO1-alpha-mediated stimulation of inositol 1,4,5-triphosphate receptor activity in endoplasmic reticulum stress-induced apoptosis

12 July 2018

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12 July 2018

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Effects of glutathione reductase inhibition on cellular thiol redox state and related systems

12 July 2018

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Cu, Zn superoxide dismutase and NADP(H) homeostasis are required for tolerance of endoplasmic reticulum stress in Saccharomyces cerevisiae

12 July 2018

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UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

12 July 2018

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Characterization of a novel dithiocarbamate glutathione reductase inhibitor and its use as a tool to modulate intracellular glutathione

12 July 2018

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Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions

12 July 2018

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Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

12 July 2018

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The biochemistry, metabolism and inherited defects of the pentose phosphate pathway: a review

12 July 2018

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Glutathione in liver diseases and hepatotoxicity

12 July 2018

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Regulation of hepatic lipogenesis by the transcription factor XBP1

12 July 2018

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Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

12 July 2018

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Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis

12 July 2018

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Deletion of hexose-6-phosphate dehydrogenase activates the unfolded protein response pathway and induces skeletal myopathy

12 July 2018

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ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

12 July 2018

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Signal integration in the endoplasmic reticulum unfolded protein response

12 July 2018

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2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells

12 July 2018

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Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

12 July 2018

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CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

12 July 2018

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Requirement of the p38 mitogen-activated protein kinase signalling pathway for the induction of the 78 kDa glucose-regulated protein/immunoglobulin heavy-chain binding protein by azetidine stress: activating transcription factor 6 as a target [...]

12 July 2018

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Etomoxir-induced oxidative stress in HepG2 cells detected by differential gene expression is confirmed biochemically

12 July 2018

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Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha

12 July 2018

1 reference

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Role of AMP-activated protein kinase in mechanism of metformin action

12 July 2018

1 reference

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Very-low-density lipoprotein assembly and secretion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290641

Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290641

The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290641

Role of disulfide bridges formed in the luminal domain of ATF6 in sensing endoplasmic reticulum stress

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290641

Peroxisomal proliferator-activated receptor alpha deficiency diminishes insulin-responsiveness of gluconeogenic/glycolytic/pentose gene expression and substrate cycle flux.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290641

Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290641

Cellular redox changes and response to drugs and toxic agents

25 September 2018

1 reference

12 December 2020

Use of a selective inhibitor of liver carnitine palmitoyltransferase I (CPT I) allows quantification of its contribution to total CPT I activity in rat heart. Evidence that the dominant cardiac CPT I isoform is identical to the skeletal muscle enzym

1 reference

12 December 2020

On the mechanism of interaction of steroids with human glucose 6-phosphate dehydrogenase

1 reference

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Consequences of mitochondrial injury induced by pharmaceutical fatty acid oxidation inhibitors is characterized in human and rat liver slices

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E11-12-1011

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10 August 2017

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10 August 2017

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