(Q35795164)

English

Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice

scientific article published on 13 October 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

atherosclerosis

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based on heuristic

inferred from title

24

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Andreas Zirlik

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Timoteo Marchini

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Timoteo Marchini

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Dennis Wolf

1

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Karlheinz Peter

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Karlheinz Peter

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object named as

Christoph Bode

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10 August 2017

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Peter Libby

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10 August 2017

Daniel Duerschmied

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object named as

Daniel Duerschmied

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10 August 2017

author name string

Jan-David Hohmann

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10 August 2017

Ansgar Wiedemann

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10 August 2017

Kamila Bledzka

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Hermann Blankenbach

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Katharina Gutte

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Katharina Zeschky

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Nicole Bassler

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Natalie Hoppe

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10 August 2017

Alexandra Ortiz Rodriguez

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Nadine Herr

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10 August 2017

Ingo Hilgendorf

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Peter Stachon

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Florian Willecke

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10 August 2017

Constantin von zur Muhlen

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Dmitry A Soloviev

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10 August 2017

Li Zhang

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10 August 2017

Edward F Plow

21

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10 August 2017

publication date

13 October 2011

1 reference

Europe PubMed Central

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10 August 2017

Circulation Research

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

109

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10 August 2017

11

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10 August 2017

1269-1279

1 reference

Europe PubMed Central

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10 August 2017

Nonsteroidal antiinflammatory drugs: past, present and future

1 reference

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Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial

1 reference

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12 July 2018

CD40-CD40L cross-talk integrates strong antigenic signals and microbial stimuli to induce development of IL-17-producing CD4+ T cells

1 reference

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12 July 2018

A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin

1 reference

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12 July 2018

CD40 ligand binds to alpha5beta1 integrin and triggers cell signaling

1 reference

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12 July 2018

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Platelets in inflammation and atherogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Molecular mechanics and dynamics of leukocyte recruitment during inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

The role of CD40-CD154 interactions in autoimmunity and the benefit of disrupting this pathway

1 reference

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12 July 2018

Promotion of leukocyte adhesion by a novel interaction between vitronectin and the beta2 integrin Mac-1 (alphaMbeta2, CD11b/CD18).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Leukocyte engagement of fibrin(ogen) via the integrin receptor alphaMbeta2/Mac-1 is critical for host inflammatory response in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

CD40/CD154 interactions at the interface of tolerance and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Targeting platelet-leukocyte interactions: identification of the integrin Mac-1 binding site for the platelet counter receptor glycoprotein Ibalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Inflammation in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Integrin activation and structural rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Control of leukocyte rolling velocity in TNF-alpha-induced inflammation by LFA-1 and Mac-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Identification of the binding site for fibrinogen recognition peptide gamma 383-395 within the alpha(M)I-domain of integrin alpha(M)beta2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Ligand binding to integrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Heparin inhibits ligand binding to the leukocyte integrin Mac-1 (CD11b/CD18).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

A discrete site modulates activation of I domains. Application to integrin alphaMbeta2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Solvent-accessible residues on the metal ion-dependent adhesion site face of integrin CR3 mediate its binding to the neutrophil inhibitory factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

The I domain is a major recognition site on the leukocyte integrin Mac-1 (CD11b/CD18) for four distinct adhesion ligands.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

12 July 2018

Identification of residues on CD40 and its ligand which are critical for the receptor-ligand interaction

1 reference

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Identification of a C3bi-specific membrane complement receptor that is expressed on lymphocytes, monocytes, neutrophils, and erythrocytes.

1 reference

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Cooperative interactions of LFA-1 and Mac-1 with intercellular adhesion molecule-1 in facilitating adherence and transendothelial migration of human neutrophils in vitro

1 reference

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12 July 2018

A unique recognition site mediates the interaction of fibrinogen with the leukocyte integrin Mac-1 (CD11b/CD18).

1 reference

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12 July 2018

Binding of the integrin Mac-1 (CD11b/CD18) to the third immunoglobulin-like domain of ICAM-1 (CD54) and its regulation by glycosylation

1 reference

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12 July 2018

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

1 reference

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25 September 2018

Role of TNF priming and adhesion molecules in neutrophil recruitment to intravascular immune complexes

1 reference

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25 September 2018

CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

25 September 2018

Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

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Delineation of the key amino acids involved in neutrophil inhibitory factor binding to the I-domain supports a mosaic model for the capacity of integrin alphaMbeta 2 to recognize multiple ligands

1 reference

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Determination of carbohydrate structures N-linked to soluble CD154 and characterization of the interactions of CD40 with CD154 expressed in Pichia pastoris and Chinese hamster ovary cells

1 reference

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The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40.

1 reference

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25 September 2018

Requirement for CD154 in the progression of atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291815

25 September 2018

T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions

1 reference

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Two leukocyte receptors (CD11a/CD18 and CD11b/CD18) mediate transient adhesion to endothelium by binding to different ligands

1 reference

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Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

12 December 2020

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CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

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inferred from PubMed ID database lookup

Soluble CD40 Ligand in Acute Coronary Syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

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inferred from PubMed ID database lookup

Analysis of gp39/CD40 interactions using molecular models and site-directed mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

12 December 2020

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inferred from PubMed ID database lookup

Identification and reconstruction of the binding site within alphaMbeta2 for a specific and high affinity ligand, NIF

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for increased collagenolysis by interstitial collagenases-1 and -3 in vulnerable human atheromatous plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

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based on heuristic

inferred from PubMed ID database lookup

Atherogenesis in mice does not require CD40 ligand from bone marrow-derived cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte CD40L deficiency affects the CD25(+) CD4 T cell population but does not affect atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21998326

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCRESAHA.111.247684

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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